Database of Protein-Protein Interactions Opens New Possibilities for Systems Biology
PrePPI uses protein structural data to predict the likelihood that any two proteins interact. Its unprecedented scope is enabling the Honig Lab to ask new kinds of biological questions.
Columbia Awarded NCI Center for Cancer Systems Biology
The Center for Cancer Systems Therapeutics (CaST) is developing a framework that can account for the dynamic nature of cancer and use this knowledge to disrupt the programs that maintain tumor survival.
Barry Honig Named ISCB Fellow
The award recognizes Honig's "seminal contributions to protein structure prediction and molecular electrostatics, and his more recent work on protein function prediction, protein-DNA recognition, and cell-cell adhesion.”
The Rise of Systems Biology
"'Science is more than a body of knowledge, it's a way of thinking,' remarked Carl Sagan, and probably his words were never more powerfully relevant than for portraying one of the newest biomedical fields, systems biology."
Uniting Structural and Systems Biology
When MAGNet was founded in 2005, one of its goals was to integrate methods from structural biology and systems biology in order to predict molecular networks. With the publication of a new algorithm for predicting protein-protein interactions, this goal has now been realized.