Brent Stockwell

Selected Publications

Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE, Patel DN, Bauer AJ, Cantley AM, Yang WS, Morrison B 3rd, Stockwell BR. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 2012 May 25;149(5):1060-72.

Herman AG, Hayano M, Poyurovsky MV, Shimada K, Skouta R, Prives C, Stockwell BR. Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay. Cancer Discov. 2011 Sep;1(4):312-25.

Wolpaw AJ, Shimada K, Skouta R, Welsch ME, Akavia UD, Pe’er D, Shaik F, Bulinski JC, Stockwell BR. Modulatory profiling identifies mechanisms of small molecule-induced cell death. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):E771-80.

Hoffstrom BG, Kaplan A, Letso R, Schmid R, Turmel GJ, Lo DC, Stockwell BR. Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins. Nat Chem Biol. 2010 Dec;6(12):900-6.

Yagoda N, von Rechenberg M, Zaganjor E, Bauer A, Yang WS, Fridman D, Wolpaw A, Smukste I, Peltier J, Boniface J, Smith R, Lessnick S, Sahasrabudhe S, Stockwell BR. RAS-RAF-MEK dependent oxidative cell death involving voltage dependent anion channels. Nature. 2007 Jun 14;447(7146):864-8.

Varma H, Voisine C, DeMarco CT, Cattaneo E, Lo DC, Hart AC, Stockwell BR. Selective inhibitors of death in mutant huntingtin cells. Nat Chem Biol. 2007 Feb;3(2):99-100.