Associate Professor, Department of Biochemistry and Molecular Biophysics
Lawrence Shapiro is an associate professor in the Department of Biochemistry and Molecular Biophysics as well as the Jules and Doris Stein Professor of Research to Prevent Blindness, at the Edward S. Harness Eye Institute. He is also a member of the Motor Neuron Center and the Naomi Berrie Diabetes Center. His laboratory uses methods from structural biology to understand protein structure and binding dynamics. His work focuses on two areas: 1) the structural biology and protein biochemistry of cadherins, a family of cell surface proteins that mediate adhesive binding between cells in both vertebrates and invertebrates, and 2) the protein chemistry and structural biology of proteins involved in energy homeostasis, particularly AMP-activated protein kinase (AMPK).