Tuuli Lappalainen

Selected Publications

Lappalainen T # , Sammeth M, Friedlander M, ‘t Hoen PAC, Rivas MA, Monlong J, Gonzalez-Porta M, Kurbatova N, Griebel T, Ferreira P, Barann M,  Wieland T, Greger L, van Iterson M, Almlof J, Ribeca P, Pulyakhina I, Esser D, Giger T, Sultan M, Bertier G, MacArthur DG, Lek M, Lizano E, Buermans H, Padioleau I, Strom T, Schwartzmayer T, Pirinen M, Karlberg O, Betran Agullo S, Gut M, Amstislavskiy V, Montgomery SB, Donnelly P, McCarthy M, The Geuvadis Consortium, Lehrach H, Schreiber S, Sudbrak R, Carracedo Alvarez A, Flicek P, Antonarakis S, Hasler R, Syvanen A-C, van Ommen G-J, Brazma A, Meitinger T, Rosenstiel P, Guigo R, Gut I, Estivill X, Dermitzakis ET #.  Transcriptome and genome sequencing uncovers human functional variation.  Nature 2013 Sep 26;501: 506-511.

’t Hoen PAC # , Friedländer MR, Almlöf J, Sammeth M, Pulyakhina I, Anvar SY, Laros JFJ, Karlberg O, The GEUVADIS Consortium, Syvänen AC, Guigó R, Estivill X, den Dunnen JT, van Ommen GJB, Dermitzakis ET, Lappalainen T #.  Reproducible transcriptome sequencing across different laboratories . Nat Biotechnol. 2013 Nov;31(11):1015-22.

Lappalainen T # , Montgomery SB, Nica AC, Dermitzakis ET # Epistatic selection between coding and regulatory variation in human evolution and disease . Am J Hum Genet. 2011 Sep 9;89(3):459-63.

Khurana E, Fu Y, Colonna V, Mu XJ, Kang HM, Lappalainen T, Lochovsky L, Chen J, Abyzov A, Balasubramanian S, Challis D, Chen Y, Clarke D, Clarke L, Das J, Dermatzikis ET, Evani U, Fragoza R, Garrison E, Gibbs R, Harmanci A, Herrero J, Kitabayashi N, Kong Y, Lage K, Lipkin S, MacArthur DG, Muzni D, Pers T, Rosenfeld JA, Rubin M, Sboner A, Sisu C, Wei X, Wilson M, Xue Y, Yu H, Yu F, 1000 Genomes Project Consortium, Tyler-Smith C, Gerstein M. Integrative Annotation of Variants from 1092 Humans: Application to Cancer Genomics . Science. 2013 Oct 4;342(6154):1235587.

The 1000 Genomes Consortium. An integrated map of genetic variation from 1,092 human genomes . Nature. 2012 Nov 1;491(7422):56-65.

Gutierrez-Arcelus M, Lappalainen T , Montgomery SB, Buil A, Ongen H, Yurovsky A, Bryois J, Giger T, Romano L, Planchon A, Falconnet E, Bielser D, Gagnebin M, Padioleau I, Borel C, Letourneau A, Makrythanasis P, Guipponi M, Gehrig C, Antonarakis SE, Dermitzakis ET. Passive and active DNA methylation and the interplay with genetic variation in gene regulation . Elife. 2013 Jun 4;2:e00523.