The Columbia University Department of Systems Biology periodically publishes a free newsletter reporting on recent research highlights and other news from our community. Previously, the newsletter was published under the auspices of the Center for Multiscale Analysis of Genetic and Cellular Networks (MAGNet). Click on the thumbnails to download a copy of the newsletter as a PDF.

Department of Systems Biology Research Highlights

 

Research Highlights 2016  

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September 2016

Columbia Awarded NCI Center for Cancer Systems Biology

Glioblastoma Tumor Evolution and Strategies against Advanced Disease
Raul Rabadan

How Genomic Data Are Changing Population Genetics
Molly Przeworski

Method for Determining Proten Function Opens Doors for Precision Medicine
Andrea Califano


 

Research Highlights 2015

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June 2015

Columbia Investigators Awarded New NCI Physical Sciences in Oncology Center 
Raul Rabadan

The Exposome: Relating Environmental Factors to Human Disease
Nicholas Tatonetti

Tracing Bacterial Evolution across Billions of Years
Dennis Vitkup

Mechanism of Kidney Transplant Tolerance Discovered
Yufeng Shen


 

Research Highlights 2014  

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December 2014

A Comprehensive Map of Human B-Cell Development
Dana Pe'er

New Directions in Genome Engineering
Harris Wang

Algorithm Identifies Genetic Driver of Mesenchymal Glioblastoma
Andrea Califano

Systems Biology Throws You Out of the Box
Saeed Tavazoie


MAGNet Newsletters

 

MAGNet Newsletter 2014  

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Spring 2014 - Featured Articles

Cross-Species Computational Analysis Identifies a Synergistic Interaction that Drives Prostate Cancer Malignancy 
Cory Abate-Shen, Andrea Califano, Michael Shen

A Topological Approach for Characterizing Evolution 
Kevin Emmett, Raul Rabadan

A Global View of Tumor-Induced Gene Expression Changes in Human Metabolism 
Dennis Vitkup


 

MAGNet Newsletter 2013  

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Spring 2013 - Featured Articles

PrePPI: A Novel Structure-Based Method for Predicting Protein-Protein Interactions 
Barry Honig

An Integrative Genomics Approach to Define RNA Regulatory Networks 
Chaolin Zhang

From Genome-Scale Sequencing to Angstrom-Scale Insights: The Enzyme DNase I Reveals Its True Colors 
Harmen J. Bussemaker


 

 

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Spring 2012 - Featured Articles

A Mesenchymal Transition Signature Present in Invasive Solid Cancers 
Dimitris Anastassiou

Discovering the Regulatory Programs Underlying Mammalian Transcript Stability 
Hani Goodarzi & Saeed Tavazoie

Mapping the miRNA Regulatory Network in Glioblastoma 
Pavel Sumazin & Andrea Califano


 

 

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Spring 2011 - Featured Articles


Interrogating Molecular Pathways of Prostate Tumorigenesis in Mice and Men 
Cory Abate-Shen & Michael M. Shen

The Origin and Evolution of a Pandemic Virus 
Zachary Carpenter, Carlos Hernandez, Joseph Chan, Raul Rabadan

The Transcriptional Network for Mesenchymal Transformation of Brain Tumours 
Andrea Califano


 

 

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Spring 2010 - Featured Articles


Structural Organization, Evolution, and Heterogeneous Activation of a Bacterial Sporulation Network 
Dennis Vitkup

Breaking the Code of Non-coding DNA in the Human Genome 
Tom Tullius

The Family of Man: Methods and Applications for Discovering Shared Ancestry among Purported Unrelateds 
Itsik Pe'er


 

 

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Winter 2009 - Featured Articles


Three R's of Computer Assisted Biomedical Discovery: Reading, Reasoning and Reporting 
Hannah Tipney & Lawrence Hunter

Dissecting Transcription Factor Function on Multiple Scales Biophysics, and Computers 
Harmen J. Bussemaker

Making Sense of Transcription Factor Specificities, or How to Grow Legs in Strange Places: a Collaboration between Flies, Biophysics, and Computers 
Richard S. Mann & Barry Honig


 

 

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Winter 2008 - Featured Articles


Understanding Cadherin Specificity in the Development of Multicellular Structures: a Combined Experimental and Computational Theory 
Lawrence Shapiro & Barry Honig

Mapping the Transcription Factor Modulator Repertoire in Human B Lymphocytes 
Andrea Califano & Riccardo Dalla-Favera

National Centers for Biomedical Computing and Related Activities at NIH 
Dan Gallahan