Search Publications

Petrey D, T Chen S, Deng L, Garzón JIgnacio, Hwang H, Lasso G, Lee H, Silkov A, Honig B.  2015.  Template-based prediction of protein function. Curr Opin Struct Biol. 32C:33-38. Go to Pubmed
Lorberbaum T, Nasir M, Keiser M, Vilar S, Hripcsak G, Tatonetti N.  2015.  Systems pharmacology augments drug safety surveillance. Clin Pharmacol Ther. 97(2):151-8. Go to Pubmed
Vidal SJ, Rodriguez-Bravo V, S Quinn A, Rodriguez-Barrueco R, Lujambio A, Williams E, Sun X, de la Iglesia-Vicente J, Lee A, Readhead B et al.  2015.  A Targetable GATA2-IGF2 Axis Confers Aggressiveness in Lethal Prostate Cancer. Cancer Cell. 27(2):223-39. Go to Pubmed
Bouchard MB, Voleti V, Mendes CS, Lacefield C, Grueber WB, Mann RS, Bruno RM, Hillman EMC.  2015.  Swept confocally-aligned planar excitation (SCAPE) microscopy for high speed volumetric imaging of behaving organisms. Nat Photonics. 9(2):113-119. Go to Pubmed
Lu Y, Xue Q, Eisele MR, Sulistijo ES, Brower K, Han L, Amir E-ADavid, Pe'er D, Miller-Jensen K, Fan R.  2015.  Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands. Proc Natl Acad Sci U S A. 112(7):E607-15. Go to Pubmed
Gutierrez-Arcelus M, Ongen H, Lappalainen T, Montgomery SB, Buil A, Yurovsky A, Bryois J, Padioleau I, Romano L, Planchon A et al.  2015.  Tissue-specific effects of genetic and epigenetic variation on gene regulation and splicing. PLoS Genet. 11(1):e1004958. Go to Pubmed
Morris H, DeWolf S, Robins H, Sprangers B, LoCascio SA, Shonts BA, Kawai T, Wong W, Yang S, Zuber J et al.  2015.  Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients. Sci Transl Med. 7(272):272ra10. Go to Pubmed
Bussemaker HJ.  2015.  Recent progress in understanding transcription factor binding specificity. Brief Funct Genomics. 14(1):1-2. Go to Pubmed
Zunder ER, Finck R, Behbehani GK, Amir E-AD, Krishnaswamy S, Gonzalez VD, Lorang CG, Bjornson Z, Spitzer MH, Bodenmiller B et al.  2015.  Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm. Nat Protoc. 10(2):316-33. Go to Pubmed
Shelanski M, Shin W, Aubry S, Sims P, Alvarez MJ, Califano A.  2015.  A systems approach to drug discovery in Alzheimer's disease. Neurotherapeutics. 12(1):126-31. Go to Pubmed
Greenfeld M, van de Meent J-W, Pavlichin DS, Mabuchi H, Wiggins CH, Gonzalez RL, Herschlag D.  2015.  Single-molecule dataset (SMD): a generalized storage format for raw and processed single-molecule data. BMC Bioinformatics. 16(1):3. Go to Pubmed
Herranz D, Ferrando AA.  2015.  An oncogenic enhancer enemy (N-Me) in T-ALL. Cell Cycle. 14(2):167-8. Go to Pubmed
Khiabanian H, Carpenter Z, Kugelman J, Chan J, Trifonov V, Nagle E, Warren T, Iversen P, Bavari S, Palacios G et al.  2014.  Viral diversity and clonal evolution from unphased genomic data. BMC Genomics. 15(Suppl 6):S17. Go to Pubmed
Crocker J, Abe N, Rinaldi L, McGregor AP, Frankel N, Wang S, Alsawadi A, Valenti P, Plaza S, Payre F et al.  2015.  Low affinity binding site clusters confer hox specificity and regulatory robustness. Cell. 160(1-2):191-203. Go to Pubmed
Abate F, Todaro M, van der Krogt J-A, Boi M, Landra I, Machiorlatti R, Tabbò F, Messana K, Abele C, Barreca A et al.  2014.  A novel patient-derived tumorgraft model with TRAF1-ALK anaplastic large-cell lymphoma translocation. Leukemia. Go to Pubmed
Kobayashi T, Owczarek TB, McKiernan JM, Abate-Shen C.  2015.  Modelling bladder cancer in mice: opportunities and challenges. Nat Rev Cancer. 15(1):42-54. Go to Pubmed
Chang J, Gilman SR, Chiang AH, Sanders SJ, Vitkup D.  2014.  Genotype to phenotype relationships in autism spectrum disorders. Nat Neurosci. Go to Pubmed
Guitart-Pla O, Kustagi M, Rügheimer F, Califano A, Schwikowski B.  2014.  The Cyni framework for network inference in Cytoscape. Bioinformatics. Go to Pubmed
Wang J, Khiabanian H, Rossi D, Fabbri G, Gattei V, Forconi F, Laurenti L, Marasca R, Del Poeta G, Foá R et al.  2014.  Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia. Elife. 3 Go to Pubmed
Rampal R, Alkalin A, Madzo J, Vasanthakumar A, Pronier E, Patel J, Li Y, Ahn J, Abdel-Wahab O, Shih A et al.  2014.  DNA Hydroxymethylation Profiling Reveals that WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia. Cell Rep. Go to Pubmed
Popadin KY, Gutierrez-Arcelus M, Lappalainen T, Buil A, Steinberg J, Nikolaev SI, Lukowski SW, Bazykin GA, Seplyarskiy VB, Ioannidis P et al.  2014.  Gene age predicts the strength of purifying selection acting on gene expression variation in humans. Am J Hum Genet. 95(6):660-74. Go to Pubmed
Mayya V, Neiswanger W, Medina R, Wiggins CH, Dustin ML.  2015.  Integrative analysis of T cell motility from multi-channel microscopy data using TIAM. J Immunol Methods. 416:84-93. Go to Pubmed
Buil A, Brown AAnand, Lappalainen T, Viñuela A, Davies MN, Zheng H-F, J Richards B, Glass D, Small KS, Durbin R et al.  2014.  Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins. Nat Genet. Go to Pubmed
Sanchez-Garcia F, Villagrasa P, Matsui J, Kotliar D, Castro V, Akavia U-D, Chen B-J, Saucedo-Cuevas L, Barrueco RRodriguez, Llobet-Navas D et al.  2014.  Integration of Genomic Data Enables Selective Discovery of Breast Cancer Drivers. Cell. Go to Pubmed
Vilar S, Uriarte E, Santana L, Friedman C, Tatonetti NP.  2014.  State of the Art and Development of a Drug-Drug Interaction Large Scale Predictor Based on 3D Pharmacophoric Similarity. Curr Drug Metab. 15(5):490-501. Go to Pubmed
Bansal M, Yang J, Karan C, Menden MP, Costello JC, Tang H, Xiao G, Li Y, Allen J, Zhong R et al.  2014.  A community computational challenge to predict the activity of pairs of compounds. Nat Biotechnol. Go to Pubmed
Davis H, Irshad S, Bansal M, Rafferty H, Boitsova T, Bardella C, Jaeger E, Lewis A, Freeman-Mills L, Giner FC et al.  2015.  Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche. Nat Med. 21(1):62-70. Go to Pubmed
Califano A.  2014.  Predicting protein networks in cancer. Nat Genet. 46(12):1252-3. Go to Pubmed
Thome JJC, Yudanin N, Ohmura Y, Kubota M, Grinshpun B, Sathaliyawala T, Kato T, Lerner H, Shen Y, Farber DL.  2014.  Spatial Map of Human T Cell Compartmentalization and Maintenance over Decades of Life. Cell. 159(4):814-28. Go to Pubmed
Gao Z, Przeworski M, Sella G.  2014.  Footprints of ancient balanced polymorphisms in genetic variation data from closely related species. Evolution. Go to Pubmed
Angeli JPedro Frie, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N, Aichler M, Walch A, Eggenhofer E et al.  2014.  Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat Cell Biol. 16(12):1180-91. Go to Pubmed
Munck C, Gumpert HK, Wallin AINilsson, Wang HH, Sommer MOA.  2014.  Prediction of resistance development against drug combinations by collateral responses to component drugs. Sci Transl Med. 6(262):262ra156. Go to Pubmed
Linkermann A, Skouta R, Himmerkus N, Mulay SR, Dewitz C, De Zen F, Prokai A, Zuchtriegel G, Krombach F, Welz P-S et al.  2014.  Synchronized renal tubular cell death involves ferroptosis. Proc Natl Acad Sci U S A. Go to Pubmed
Vardarajan BN, Zhang Y, Lee JH, Cheng R, Bohm C, Ghani M, Reitz C, Reyes-Dumeyer D, Shen Y, Rogaeva E et al.  2015.  Coding mutations in SORL1 and Alzheimer disease. Ann Neurol. 77(2):215-27. Go to Pubmed
Chiu H-S, Llobet-Navas D, Yang X, Chung W-J, Ambesi-Impiombato A, Iyer A, Kim HRyan, Seviour EG, Luo Z, Sehgal V et al.  2014.  Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks. Genome Res. Go to Pubmed
Plata G, Henry CS, Vitkup D.  2015.  Long-term phenotypic evolution of bacteria. Nature. 517(7534):369-72. Go to Pubmed
Mingueneau M, Krishnaswamy S, Spitzer MH, Bendall SC, Stone EL, Hedrick SM, Pe'er D, Mathis D, Nolan GP, Benoist C.  2014.  Single-cell mass cytometry of TCR signaling: Amplification of small initial differences results in low ERK activation in NOD mice. Proc Natl Acad Sci U S A. Go to Pubmed
Mendes CS, Rajendren SV, Bartos I, Márka S, Mann RS.  2014.  Kinematic Responses to Changes in Walking Orientation and Gravitational Load in Drosophila melanogaster. PLoS One. 9(10):e109204. Go to Pubmed
Parfitt D-E, Shen MM.  2014.  From blastocyst to gastrula: gene regulatory networks of embryonic stem cells and early mouse embryogenesis. Philos Trans R Soc Lond B Biol Sci. 369(1657) Go to Pubmed
Yang K-A, Barbu M, Halim M, Pallavi P, Kim B, Kolpashchikov DM, Pecic S, Taylor S, Worgall TS, Stojanovic MN.  2014.  Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors. Nat Chem. 6(11):1003-8. Go to Pubmed
Krishnaswamy S, Spitzer MH, Mingueneau M, Bendall SC, Litvin O, Stone E, Pe'er D, Nolan GP.  2014.  Conditional density-based analysis of T cell signaling in single-cell data. Science. Go to Pubmed
Kushwaha R, Jagadish N, Kustagi M, Tomishima MJ, Mendiratta G, Bansal M, Kim HR, Sumazin P, Alvarez MJ, Lefebvre C et al.  2014.  Interrogation of a context-specific transcription factor network identifies novel regulators of pluripotency. Stem Cells. Go to Pubmed
Linkermann A, Stockwell BR, Krautwald S, Anders H-J.  2014.  Regulated cell death and inflammation: an auto-amplification loop causes organ failure. Nat Rev Immunol. Go to Pubmed
Machado ACarolina D, Zhou T, Rao S, Goel P, Rastogi C, Lazarovici A, Bussemaker HJ, Rohs R.  2014.  Evolving insights on how cytosine methylation affects protein-DNA binding. Brief Funct Genomics. Go to Pubmed
Boutros PC, Margolin AA, Stuart JM, Califano A, Stolovitzky G.  2014.  Toward better benchmarking: challenge-based methods assessment in cancer genomics. Genome Biol. 15(9):462. Go to Pubmed
Giorgi FM, Lopez G, Woo JH, Bisikirska B, Califano A, Bansal M.  2014.  Inferring protein modulation from gene expression data using conditional mutual information. PLoS One. 9(10):e109569. Go to Pubmed
Oren Y, Smith MB, Johns NI, Zeevi MKaplan, Biran D, Ron EZ, Corander J, Wang HH, Alm EJ, Pupko T.  2014.  Transfer of noncoding DNA drives regulatory rewiring in bacteria. Proc Natl Acad Sci U S A. Go to Pubmed
Chen JC, Alvarez MJ, Talos F, Dhruv H, Rieckhof GE, Iyer A, Diefes KL, Aldape K, Berens M, Shen MM et al.  2014.  Identification of Causal Genetic Drivers of Human Disease through Systems-Level Analysis of Regulatory Networks. Cell. 159(2):402-14. Go to Pubmed
Lee A, Khiabanian H, Kugelman J, Elliott O, Nagle E, Yu G-Y, Warren T, Palacios G, Rabadan R.  2014.  Transcriptome reconstruction and annotation of cynomolgus and African green monkey. BMC Genomics. 15(1):846. Go to Pubmed
Batra R, Charizanis K, Manchanda M, Mohan A, Li M, Finn DJ, Goodwin M, Zhang C, Sobczak K, Thornton CA et al.  2014.  Loss of MBNL Leads to Disruption of Developmentally Regulated Alternative Polyadenylation in RNA-Mediated Disease. Mol Cell. Go to Pubmed
Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR et al.  2014.  Unraveling the mechanism of cell death induced by chemical fibrils. Nat Chem Biol. Go to Pubmed
Hoffman KB, Demakas AR, Dimbil M, Tatonetti NP, Erdman CB.  2014.  Stimulated Reporting: The Impact of US Food and Drug Administration-Issued Alerts on the Adverse Event Reporting System (FAERS). Drug Saf. Go to Pubmed
Vendome J, Felsovalyi K, Song H, Yang Z, Jin X, Brasch J, Harrison OJ, Ahlsen G, Bahna F, Kaczynska A et al.  2014.  Structural and energetic determinants of adhesive binding specificity in type I cadherins. Proc Natl Acad Sci U S A. Go to Pubmed
Vilar S, Ryan PB, Madigan D, Stang PE, Schuemie MJ, Friedman C, Tatonetti NP, Hripcsak G.  2014.  Similarity-based modeling applied to signal detection in pharmacovigilance. CPT Pharmacometrics Syst Pharmacol. 3:e137. Go to Pubmed
Yang T-HOu, Cheng W-Y, Zheng T, Maurer MA, Anastassiou D.  2014.  Breast Cancer Prognostic Biomarker Using Attractor Metagenes and the FGD3-SUSD3 Metagene. Cancer Epidemiol Biomarkers Prev. Go to Pubmed
Chua CWai, Shibata M, Lei M, Toivanen R, Barlow LJ, Bergren SK, Badani KK, McKiernan JM, Benson MC, Hibshoosh H et al.  2014.  Single luminal epithelial progenitors can generate prostate organoids in culture. Nat Cell Biol. Go to Pubmed
Panousis NI, Gutierrez-Arcelus M, Dermitzakis ET, Lappalainen T.  2014.  Allelic mapping bias in RNA-sequencing is not a major confounder in eQTL studies. Genome Biol. 15(9):467. Go to Pubmed
Kreimer A, Pe'er I.  2014.  Co-regulated Transcripts Associated to Cooperating eSNPs Define Bi-fan Motifs in Human Gene Networks. PLoS Genet. 10(9):e1004587. Go to Pubmed
Glessner J, Bick AG, Ito K, Homsy J, Rodriguez-Murillo L, Fromer M, Mazaika EJ, Vardarajan B, Italia MJ, Leipzig J et al.  2014.  Increased Frequency of De Novo Copy Number Variations in Congenital Heart Disease by Integrative Analysis of SNP Array and Exome Sequence Data. Circ Res. Go to Pubmed
Carmi S, Hui KY, Kochav E, Liu X, Xue J, Grady F, Guha S, Upadhyay K, Ben-Avraham D, Mukherjee S et al.  2014.  Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins. Nat Commun. 5:4835. Go to Pubmed
Herranz D, Ambesi-Impiombato A, Palomero T, Schnell SA, Belver L, Wendorff AA, Xu L, Castillo-Martin M, Llobet-Navas D, Cordon-Cardo C et al.  2014.  A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia. Nat Med. 20(10):1130-7. Go to Pubmed
Zhang Y, Chen K, Sloan SA, Bennett ML, Scholze AR, O'Keeffe S, Phatnani HP, Guarnieri P, Caneda C, Ruderisch N et al.  2014.  An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex. J Neurosci. 34(36):11929-47. Go to Pubmed
Abate F, Zairis S, Ficarra E, Acquaviva A, Wiggins CH, Frattini V, Lasorella A, Iavarone A, Inghirami G, Rabadan R.  2014.  Pegasus: a comprehensive annotation and prediction tool for detection of driver gene fusions in cancer. BMC Syst Biol. 8(1):97. Go to Pubmed
Wang ZA, Toivanen R, Bergren SK, Chambon P, Shen MM.  2014.  Luminal Cells Are Favored as the Cell of Origin for Prostate Cancer. Cell Rep. Go to Pubmed
Thu CAye, Chen WV, Rubinstein R, Chevee M, Wolcott HN, Felsovalyi KO, Tapia JCarlos, Shapiro L, Honig B, Maniatis T.  2014.  Single-Cell Identity Generated by Combinatorial Homophilic Interactions between α, β, and γ Protocadherins. Cell. 158(5):1045-59. Go to Pubmed
van Arensbergen J, van Steensel B, Bussemaker HJ.  2014.  In search of the determinants of enhancer-promoter interaction specificity. Trends Cell Biol. Go to Pubmed
Agelopoulos M, McKay DJ, Mann RS.  2014.  cgChIP: A Cell Type- and Gene-Specific Method for Chromatin Analysis. Methods Mol Biol. 1196:291-306. Go to Pubmed
Riley TR, Slattery M, Abe N, Rastogi C, Liu D, Mann RS, Bussemaker HJ.  2014.  SELEX-seq: A Method for Characterizing the Complete Repertoire of Binding Site Preferences for Transcription Factor Complexes. Methods Mol Biol. 1196:255-78. Go to Pubmed
Carr A, Pe'er D.  2014.  Broadening horizons: holistic viewpoints from the Biology of Genomes. Genome Biol. 15(7):416. Go to Pubmed
Greger L, Su J, Rung J, Ferreira PG, Lappalainen T, Dermitzakis ET, Brazma A.  2014.  Tandem RNA chimeras contribute to transcriptome diversity in human population and are associated with intronic genetic variants. PLoS One. 9(8):e104567. Go to Pubmed
Gonzalez C, Sims JS, Hornstein N, Mela A, Garcia F, Lei L, Gass DA, Amendolara B, Bruce JN, Canoll P et al.  2014.  Ribosome profiling reveals a cell-type-specific translational landscape in brain tumors. J Neurosci. 34(33):10924-36. Go to Pubmed
Martin AR, Costa HA, Lappalainen T, Henn BM, Kidd JM, Yee M-C, Grubert F, Cann HM, Snyder M, Montgomery SB et al.  2014.  Transcriptome sequencing from diverse human populations reveals differentiated regulatory architecture. PLoS Genet. 10(8):e1004549. Go to Pubmed
Johnson S, van de Meent J-W, Phillips R, Wiggins CH, Lindén M.  2014.  Multiple LacI-mediated loops revealed by Bayesian statistics and tethered particle motion. Nucleic Acids Res. 42(16):10265-77. Go to Pubmed
Pefanis E, Wang J, Rothschild G, Lim J, Chao J, Rabadan R, Economides AN, Basu U.  2014.  Noncoding RNA transcription targets AID to divergently transcribed loci in B cells. Nature. Go to Pubmed
Gill BJ, Pisapia DJ, Malone HR, Goldstein H, Lei L, Sonabend A, Yun J, Samanamud J, Sims JS, Banu M et al.  2014.  MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma. Proc Natl Acad Sci U S A. 111(34):12550-5. Go to Pubmed
Wang J, Abate-Shen C.  2014.  Analyses of tumor-suppressor genes in germline mouse models of cancer. Cold Spring Harb Protoc. 2014(8):pdb.top069773. Go to Pubmed
Lim ET, Würtz P, Havulinna AS, Palta P, Tukiainen T, Rehnström K, Esko T, Mägi R, Inouye M, Lappalainen T et al.  2014.  Distribution and medical impact of loss-of-function variants in the Finnish founder population. PLoS Genet. 10(7):e1004494. Go to Pubmed
Wolpaw AJ, Stockwell BR.  2014.  Multidimensional profiling in the investigation of small-molecule-induced cell death. Methods Enzymol. 545:265-302. Go to Pubmed
Matos MJoão, Vilar S, Kachler S, Fonseca A, Santana L, Uriarte E, Borges F, Tatonetti NP, Klotz K-N.  2014.  Insight into the Interactions between Novel Coumarin Derivatives and Human A3 Adenosine Receptors. ChemMedChem. Go to Pubmed
Goodarzi H, Zhang S, Buss CG, Fish L, Tavazoie S, Tavazoie SF.  2014.  Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins. Nature. Go to Pubmed
Overby CLynnette, Hripcsak G, Shen Y.  2014.  Estimating heritability of drug-induced liver injury from common variants and implications for future study designs. Sci Rep. 4:5762. Go to Pubmed
Woods DP, Ream TS, Minevich G, Hobert O, Amasino RM.  2014.  PHYTOCHROME C Is an Essential Light Receptor for Photoperiodic Flowering in the Temperate Grass, Brachypodium distachyon. Genetics. 198(1):397-408. Go to Pubmed
Oh H, Slattery M, Ma L, White KP, Mann RS, Irvine KD.  2014.  Yorkie Promotes Transcription by Recruiting a Histone Methyltransferase Complex. Cell Rep. Go to Pubmed
Segurel L, Wyman MJ, Przeworski M.  2014.  Determinants of Mutation Rate Variation in the Human Germline. Annu Rev Genomics Hum Genet. Go to Pubmed
Higgins CA, Petukhova L, Harel S, Ho YY, Drill E, Shapiro L, Wajid M, Christiano AM.  2014.  FGF5 is a crucial regulator of hair length in humans. Proc Natl Acad Sci U S A. Go to Pubmed
Boyce RD, Ryan PB, G Norén N, Schuemie MJ, Reich C, Duke J, Tatonetti NP, Trifirò G, Harpaz R, J Overhage M et al.  2014.  Bridging Islands of Information to Establish an Integrated Knowledge Base of Drugs and Health Outcomes of Interest. Drug Saf. Go to Pubmed
Repunte-Canonigo V, Lefebvre C, George O, Kawamura T, Morales M, Koob GF, Califano A, Masliah E, Sanna PPaolo.  2014.  Gene expression changes consistent with neuroAIDS and impaired working memory in HIV-1 transgenic rats. Mol Neurodegener. 9:26. Go to Pubmed
Ghosh HS, Ceribelli M, Matos I, Lazarovici A, Bussemaker HJ, Lasorella A, Hiebert SW, Liu K, Staudt LM, Reizis B.  2014.  ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2. J Exp Med. Go to Pubmed
The Genome of the Netherlands Consortium.  2014.  Whole-genome sequence variation, population structure and demographic history of the Dutch population. Nat Genet. Go to Pubmed
Ward LD, Wang J, Bussemaker HJ.  2014.  Characterizing a collective and dynamic component of chromatin immunoprecipitation enrichment profiles in yeast. BMC Genomics. 15(1):494. Go to Pubmed
Mukherjee S, Guha S, Ikeda M, Iwata N, Malhotra A, Pe'er I, Darvasi A, Lencz T.  2014.  Excess of homozygosity in the major histocompatibility complex in schizophrenia. Hum Mol Genet. Go to Pubmed
Fazlollahi M, Lee E, Muroff I, Lu X-J, Gomez-Alcala P, Causton HC, Bussemaker HJ.  2014.  Harnessing Natural Sequence Variation to Dissect Post-Transcriptional Regulatory Networks in Yeast. G3 (Bethesda). Go to Pubmed
Sciara G, Clarke OB, Tomasek D, Kloss B, Tabuso S, Byfield R, Cohn R, Banerjee S, Rajashankar KR, Slavkovic V et al.  2014.  Structural basis for catalysis in a CDP-alcohol phosphotransferase. Nat Commun. 5:4068. Go to Pubmed
Shan Y, Gnanasambandan K, Ungureanu D, Kim ET, Hammarén H, Yamashita K, Silvennoinen O, Shaw DE, Hubbard SR.  2014.  Molecular basis for pseudokinase-dependent autoinhibition of JAK2 tyrosine kinase. Nat Struct Mol Biol. Go to Pubmed
Petrey D, Honig B.  2014.  Structural bioinformatics of the interactome. Annu Rev Biophys. 43:193-210. Go to Pubmed
Costello JC, Heiser LM, Georgii E, Gönen M, Menden MP, Wang NJ, Bansal M, Ammad-Ud-Din M, Hintsanen P, Khan SA et al.  2014.  A community effort to assess and improve drug sensitivity prediction algorithms. Nat Biotechnol. Go to Pubmed
Stojanovic MN, Stefanovic D, Rudchenko S.  2014.  Exercises in Molecular Computing. Acc Chem Res. Go to Pubmed
Iliadis A, Anastassiou D, Wang X.  2014.  A sequential Monte Carlo framework for haplotype inference in CNV/SNP genotype data. EURASIP J Bioinform Syst Biol. 2014(1):7. Go to Pubmed
Bonde MT, Kosuri S, Genee HJ, Sarup-Lytzen K, Church GM, Sommer MOA, Wang HH.  2014.  Direct Mutagenesis of Thousands of Genomic Targets using Microarray-derived Oligonucleotides. ACS Synth Biol. Go to Pubmed
Dixon SJ, Patel DN, Welsch M, Skouta R, Lee ED, Hayano M, Thomas AG, Gleason CE, Tatonetti N, Slusher BS et al.  2014.  Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis. Elife. :e02523. Go to Pubmed

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