Search Publications

Vacic V, Ozelius LJ, Clark LN, Bar-Shira A, Gana-Weisz M, Gurevich T, Gusev A, Kedmi M, Kenny EE, Liu X et al.  2014.  Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes. Hum Mol Genet. Go to Pubmed
Yaung SJ, Church GM, Wang HH.  2014.  Recent progress in engineering human-associated microbiomes. Methods Mol Biol. 1151:3-25. Go to Pubmed
Aydin IT, Melamed R, Adams SJ, Castillo-Martin M, Demir A, Bryk D, Brunner G, Cordon-Cardo C, Osman I, Rabadan R et al.  2014.  FBXW7 Mutations in Melanoma and a New Therapeutic Paradigm. J Natl Cancer Inst. 106(6) Go to Pubmed
Bonde MT, Klausen MS, Anderson MV, Wallin AIN, Wang HH, Sommer MOA.  2014.  MODEST: a web-based design tool for oligonucleotide-mediated genome engineering and recombineering. Nucleic Acids Res. Go to Pubmed
Shetzer Y, Kagan S, Koifman G, Sarig R, Kogan-Sakin I, Charni M, Kaufman T, Zapatka M, Molchadsky A, Rivlin N et al.  2014.  The onset of p53 loss of heterozygosity is differentially induced in various stem cell types and may involve the loss of either allele. Cell Death Differ. Go to Pubmed
Aytes A, Mitrofanova A, Lefebvre C, Alvarez MJ, Castillo-Martin M, Zheng T, Eastham JA, Gopalan A, Pienta KJ, Shen MM et al.  2014.  Cross-Species Regulatory Network Analysis Identifies a Synergistic Interaction between FOXM1 and CENPF that Drives Prostate Cancer Malignancy. Cancer Cell. 25(5):638-51. Go to Pubmed
Li L, Ruau DJ, Patel CJ, Weber SC, Chen R, Tatonetti N, Dudley JT, Butte AJ.  2014.  Disease risk factors identified through shared genetic architecture and electronic medical records. Sci Transl Med. 6(234):234ra57. Go to Pubmed
Califano A, Kellis M, Stolovitzky G.  2014.  RECOMB/ISCB Systems Biology, Regulatory Genomics, and DREAM 2013 Special Issue. J Comput Biol. 21(5):371-2. Go to Pubmed
Delogu G, Serra S, Quezada E, Uriarte E, Vilar S, Tatonetti N, Viña D.  2014.  Monoamine Oxidase (MAO) Inhibitory Activity: 3-Phenylcoumarins versus 4-Hydroxy-3-phenylcoumarins. ChemMedChem. Go to Pubmed
Mee MT, Collins JJ, Church GM, Wang HH.  2014.  Syntrophic exchange in synthetic microbial communities. Proc Natl Acad Sci U S A. Go to Pubmed
Brown AAnand, Buil A, Viñuela A, Lappalainen T, Zheng H-F, J Richards B, Small KS, Spector TD, Dermitzakis ET, Durbin R.  2014.  Genetic interactions affecting human gene expression identified by variance association mapping. Elife. 3:e01381. Go to Pubmed
Backenroth D, Homsy J, Murillo LR, Glessner J, Lin E, Brueckner M, Lifton R, Goldmuntz E, Chung WK, Shen Y.  2014.  CANOES: detecting rare copy number variants from whole exome sequencing data. Nucleic Acids Res. Go to Pubmed
Bendall SC, Davis KL, Amir E-ADavid, Tadmor MD, Simonds EF, Chen TJ, Shenfeld DK, Nolan GP, Pe'er D.  2014.  Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development. Cell. 157(3):714-25. Go to Pubmed
Miller CP, Thorpe JD, Kortum AN, Coy CM, Cheng W-Y, Yang T-HOu, Anastassiou D, J Beatty D, Urban ND, C Blau A.  2014.  JAK2 expression is associated with tumor-infiltrating lymphocytes and improved breast cancer outcomes: implications for evaluating JAK2 inhibitors. Cancer Immunol Res. 2(4):301-6. Go to Pubmed
Matos MJoão, Vilar S, García-Morales V, Tatonetti N, Uriarte E, Santana L, Viña D.  2014.  Insight into the Functional and Structural Properties of 3-Arylcoumarin as an Interesting Scaffold in Monoamine Oxidase B Inhibition. ChemMedChem. Go to Pubmed
Lee E, de Ridder J, Kool J, Wessels LFA, Bussemaker H.  2014.  Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis. Proc Natl Acad Sci U S A. 111(15):5747-52. Go to Pubmed
Mann RS.  2014.  Neuroscience. The Michael Jackson fly. Science. 344(6179):48-9. Go to Pubmed
Kermany AR, Segurel L, Oliver TR, Przeworski M.  2014.  TroX: a new method to learn about the genesis of aneuploidy from trisomic products of conception. Bioinformatics. Go to Pubmed
Oikonomou P, Goodarzi H, Tavazoie S.  2014.  Systematic Identification of Regulatory Elements in Conserved 3' UTRs of Human Transcripts. Cell Rep. Go to Pubmed
van de Meent J-W, Bronson JE, Wiggins C, Gonzalez RL.  2014.  Empirical Bayes Methods Enable Advanced Population-Level Analyses of Single-Molecule FRET Experiments. Biophys J. 106(6):1327-37. Go to Pubmed
Hoffman KB, Dimbil M, Erdman CB, Tatonetti N, Overstreet BM.  2014.  The Weber Effect and the United States Food and Drug Administration's Adverse Event Reporting System (FAERS): Analysis of Sixty-Two Drugs Approved from 2006 to 2010. Drug Saf. Go to Pubmed
Sonabend AM, Carminucci A, Amendolara B, Bansal M, Leung R, Lei L, Realubit R, Li H, Karan C, Yun J et al.  2014.  Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma. Neuro Oncol. Go to Pubmed
Llobet-Navas D, Rodriguez-Barrueco R, Castro V, Ugalde AP, Sumazin P, Jacob-Sendler D, Demircan B, Castillo-Martin M, Putcha P, Marshall N et al.  2014.  The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland. Genes Dev. Go to Pubmed
Matos MJoão, Janeiro P, Franco RMaría Gon, Vilar S, Tatonetti N, Santana L, Uriarte E, Borges F, Fontenla JAngel, Viña D.  2014.  Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases. Future Med Chem. 6(4):371-83. Go to Pubmed
Sundling C, Zhang Z, Phad GE, Sheng Z, Wang Y, Mascola JR, Li Y, Wyatt RT, Shapiro L, Hedestam GBKarlsson.  2014.  Single-Cell and Deep Sequencing of IgG-Switched Macaque B Cells Reveal a Diverse Ig Repertoire following Immunization. J Immunol. Go to Pubmed
Weyn-Vanhentenryck SM, Mele A, Yan Q, Sun S, Farny N, Zhang Z, Xue C, Herre M, Silver PA, Zhang MQ et al.  2014.  HITS-CLIP and Integrative Modeling Define the Rbfox Splicing-Regulatory Network Linked to Brain Development and Autism. Cell Rep. Go to Pubmed
Skouta R, Dixon SJ, Wang J, Dunn DE, Orman M, Shimada K, Rosenberg P, Lo D, Weinberg J, Linkermann A et al.  2014.  Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models. J Am Chem Soc. Go to Pubmed
Trifonov V, Pasqualucci L, Tiacci E, Falini B, Rabadan R.  2013.  SAVI: a statistical algorithm for variant frequency identification. BMC Syst Biol. 7 Suppl 2:S2. Go to Pubmed
Messina M, Del Giudice I, Khiabanian H, Rossi D, Chiaretti S, Rasi S, Spina V, Holmes A, Marinelli M, Fabbri G et al.  2014.  Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness. Blood. Go to Pubmed
Song F, Del Pozo CHurtado, Rosario R, Zou YShan, Ananthakrishnan R, Xu X, Patel PR, Benoit VM, Yan SFang, Li H et al.  2014.  RAGE Regulates the Metabolic and Inflammatory Response to High Fat Feeding in Mice. Diabetes. Go to Pubmed
Karczewski KJ, Snyder M, Altman R, Tatonetti N.  2014.  Coherent functional modules improve transcription factor target identification, cooperativity prediction, and disease association. PLoS Genet. 10(2):e1004122. Go to Pubmed
Jang ISock, Margolin A, Califano A.  2013.  hARACNe: improving the accuracy of regulatory model reverse engineering via higher-order data processing inequality tests. Interface Focus. 3(4):20130011. Go to Pubmed
Rossi D, Khiabanian H, Spina V, Ciardullo C, Bruscaggin A, Famà R, Rasi S, Monti S, Deambrogi C, De Paoli L et al.  2014.  Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia. Blood. Go to Pubmed
Kurki MI, Gaál EIlona, Kettunen J, Lappalainen T, Menelaou A, Anttila V, Hof FNG van 't, Fraunberg Mvon Und Zu, Helisalmi S, Hiltunen M et al.  2014.  High risk population isolate reveals low frequency variants predisposing to intracranial aneurysms. PLoS Genet. 10(1):e1004134. Go to Pubmed
Piana S, Klepeis JL, Shaw DE.  2014.  Assessing the accuracy of physical models used in protein-folding simulations: quantitative evidence from long molecular dynamics simulations. Curr Opin Struct Biol. 24C:98-105. Go to Pubmed
Chudnovsky Y, Kim D, Zheng S, Whyte WA, Bansal M, Bray M-A, Gopal S, Theisen MA, Bilodeau S, Thiru P et al.  2014.  ZFHX4 Interacts with the NuRD Core Member CHD4 and Regulates the Glioblastoma Tumor-Initiating Cell State. Cell Rep. Go to Pubmed
Yang WSeok, Sriramaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, Cheah JH, Clemons PA, Shamji AF, Clish CB et al.  2014.  Regulation of Ferroptotic Cancer Cell Death by GPX4. Cell. 156(1-2):317-31. Go to Pubmed
Kode A, Manavalan JS, Mosialou I, Bhagat G, Rathinam CV, Luo N, Khiabanian H, Lee A, Murty VV, Friedman R et al.  2014.  Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts. Nature. Go to Pubmed
Palomero T, Couronné L, Khiabanian H, Kim M-Y, Ambesi-Impiombato A, Perez-Garcia A, Carpenter Z, Abate F, Allegretta M, J Haydu E et al.  2014.  Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas. Nat Genet. Go to Pubmed
Moore MJ, Zhang C, Gantman EConn, Mele A, Darnell JC, Darnell RB.  2014.  Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis. Nat Protoc. 9(2):263-93. Go to Pubmed
Tepper RG, Murphy CT, Bussemaker H.  2014.  DAF-16 and PQM-1: Partners in longevity. Aging (Albany NY). Go to Pubmed
Sonabend AM, Bansal M, Guarnieri P, Lei L, Amendolara B, Soderquist C, Leung R, Yun J, Kennedy B, Sisti J et al.  2014.  The Transcriptional Regulatory Network of Proneural Glioma Determines the Genetic Alterations Selected During Tumor Progression. Cancer Res. Go to Pubmed
Pasqualucci L, Khiabanian H, Fangazio M, Vasishtha M, Messina M, Holmes A, Ouillette P, Trifonov V, Rossi D, Tabbò F et al.  2014.  Genetics of follicular lymphoma transformation. Cell Rep. 6(1):130-40. Go to Pubmed
Yu L, Bennett JT, Wynn J, Carvill GL, Cheung YHim, Shen Y, Mychaliska GB, Azarow KS, Crombleholme TM, Chung DH et al.  2014.  Whole exome sequencing identifies de novo mutations in GATA6 associated with congenital diaphragmatic hernia. J Med Genet. Go to Pubmed
Dixon SJ, Stockwell BR.  2013.  The Role of Iron and Reactive Oxygen Secies in Cell Death. Nat Chem Biol. 10(1):9-17. Go to Pubmed
Liu L, Kim H, Casta A, Kobayashi Y, Shapiro L, Christiano AM.  2013.  Hairless Is a Histone H3K9 Demethylase. FASEB J. Go to Pubmed
Harton MD, Wingler LM, Cornish VW.  2013.  Transcriptional regulation improves the throughput of three-hybrid counter selections in Saccharomyces cerevisiae. Biotechnol J. 8(12):1485-91. Go to Pubmed
Freddolino PL, Goodarzi H, Tavazoie S.  2013.  Revealing the Genetic Basis of Natural Bacterial Phenotypic Divergence. J Bacteriol. Go to Pubmed
Piovan E, Yu J, Tosello V, Herranz D, Ambesi-Impiombato A, Da Silva ACarolina, Sanchez-Martin M, Perez-Garcia A, Rigo I, Castillo-Martin M et al.  2013.  Direct Reversal of Glucocorticoid Resistance by AKT Inhibition in Acute Lymphoblastic Leukemia. Cancer Cell. 24(6):766-76. Go to Pubmed
Plata G, Vitkup D.  2013.  Genetic Robustness and Functional Evolution of Gene Duplicates. Nucleic Acids Res. Go to Pubmed
Shazman S, Lee H, Socol Y, Mann RS, Honig B.  2014.  OnTheFly: a Database of Drosophila melanogaster Transcription Factors and Their Binding Sites. Nucleic Acids Res. 42(1):D167-71. Go to Pubmed
Waszak SM, Kilpinen H, Gschwind AR, Orioli A, Raghav SK, Witwicki RM, Migliavacca E, Yurovsky A, Lappalainen T, Hernandez N et al.  2014.  Identification and removal of low-complexity sites in allele-specific analysis of ChIP-seq data. Bioinformatics. 30(2):165-71. Go to Pubmed
Lencz T, Guha S, Liu C, Rosenfeld J, Mukherjee S, Derosse P, John M, Cheng L, Zhang C, Badner JA et al.  2013.  Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder. Nat Commun. 4:2739. Go to Pubmed
Becker-Weimann S, Xiong G, Furuta S, Han J, Kuhn I, Akavia UDavid, Pe'er D, Bissell MJ, Xu R.  2013.  NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals. Oncotarget. Go to Pubmed
Behr ER, Ritchie MD, Tanaka T, Kääb S, Crawford DC, Nicoletti P, Floratos A, Sinner MF, Kannankeril PJ, Wilde AAM et al.  2013.  Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes. PLoS One. 8(11):e78511. Go to Pubmed
Lippert RA, Predescu C, Ierardi DJ, Mackenzie KM, Eastwood MP, Dror RO, Shaw DE.  2013.  Accurate and efficient integration for molecular dynamics simulations at constant temperature and pressure. J Chem Phys. 139(16):164106. Go to Pubmed
Abate-Shen C, Pandolfi PP.  2013.  Effective utilization and appropriate selection of genetically engineered mouse models for translational integration of mouse and human trials. Cold Spring Harb Protoc. 2013(11) Go to Pubmed
Chan JMinhow, Carlsson G, Rabadan R.  2013.  Topology of viral evolution. Proc Natl Acad Sci U S A. 110(46):18566-71. Go to Pubmed
Ansari S, Binder J, Boue S, Di Fabio A, Hayes W, Hoeng J, Iskandar A, Kleiman R, Norel R, O'Neel B et al.  2013.  On crowd-verification of biological networks. Bioinform Biol Insights. 7:307-25. Go to Pubmed
Fabbri G, Khiabanian H, Holmes A, Wang J, Messina M, Mullighan CG, Pasqualucci L, Rabadan R, Dalla-Favera R.  2013.  Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome. J Exp Med. 210(11):2273-88. Go to Pubmed
Dror RO, Green HF, Valant C, Borhani DW, Valcourt JR, Pan AC, Arlow DH, Canals M, J Lane R, Rahmani R et al.  2013.  Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs. Nature. 503(7475):295-9. Go to Pubmed
Leduc CA, Crouch EE, Wilson A, Lefkowitch J, Wamelink MMC, Jakobs C, Salomons GS, Sun X, Shen Y, Chung WK.  2013.  Novel association of early onset hepatocellular carcinoma with transaldolase deficiency. JIMD Rep. Go to Pubmed
Sun X, Vilar S, Tatonetti N.  2013.  High-throughput methods for combinatorial drug discovery. Sci Transl Med. 5(205):205rv1. Go to Pubmed
Blair DR, Lyttle CS, Mortensen JM, Bearden CF, Jensen ABoeck, Khiabanian H, Melamed R, Rabadan R, Bernstam EV, Brunak S et al.  2013.  A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk. Cell. 155(1):70-80. Go to Pubmed
Weinstein JN, Collisson EA, Mills GB, Shaw KRMills, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM.  2013.  The Cancer Genome Atlas Pan-Cancer Analysis Project. Nat Genet. 45(10):1113-20. Go to Pubmed
Gagneur J, Stegle O, Zhu C, Jakob P, Tekkedil MM, Aiyar RS, Schuon A-K, Pe'er D, Steinmetz LM.  2013.  Genotype-environment interactions reveal causal pathways that mediate genetic effects on phenotype. PLoS Genet. 9(9):e1003803. Go to Pubmed
Li Y, Altorelli NL, Bahna F, Honig B, Shapiro L, Palmer AG.  2013.  Mechanism of E-cadherin dimerization probed by NMR relaxation dispersion. Proc Natl Acad Sci U S A. 110(41):16462-7. Go to Pubmed
Hernandez SL, Banerjee D, Garcia A, Kangsamaksin T, Cheng W-Y, Anastassiou D, Funahashi Y, Kadenhe-Chiweshe A, Shawber CJ, Kitajewski JK et al.  2013.  Notch and VEGF pathways play distinct but complementary roles in tumor angiogenesis. Vasc Cell. 5(1):17. Go to Pubmed
Sawyers CL, Abate-Shen C, Anderson KC, Barker A, Baselga J, Berger NA, Foti M, Jemal A, Lawrence TS, Li CI et al.  2013.  AACR Cancer Progress Report 2013. Clin Cancer Res. 19(20 Suppl):S1-S98. Go to Pubmed
Romano GHagit, Harari, iv Y, Yehuda T, Podhorzer A, Rubinstein L, Shamir R, Gottlieb A, Silberberg Y, Pe'er D, Ruppin E et al.  2013.  Environmental stresses disrupt telomere length homeostasis. PLoS Genet. 9(9):e1003721. Go to Pubmed
Mancini F, Wiggins C, Marsili M, Walczak AM.  2013.  Time-dependent information transmission in a model regulatory circuit. Phys Rev E Stat Nonlin Soft Matter Phys. 88(2):022708. Go to Pubmed
Barlow LJ, Shen MM.  2013.  SnapShot: Prostate cancer. Cancer Cell. 24(3):400.e1. Go to Pubmed
Irshad S, Bansal M, Castillo-Martin M, Zheng T, Aytes A, Wenske S, Le Magnen C, Guarnieri P, Sumazin P, Benson M et al.  2013.  A molecular signature predictive of indolent prostate cancer. Sci Transl Med. 5(202):202ra122. Go to Pubmed
Anton BP, Chang Y-C, Brown P, Choi H-P, Faller LL, Guleria J, Hu Z, Klitgord N, Levy-Moonshine A, Maksad A et al.  2013.  The COMBREX project: design, methodology, and initial results. PLoS Biol. 11(8):e1001638. Go to Pubmed
Jajamovich GH, Iliadis A, Anastassiou D, Wang X.  2013.  Maximum-parsimony haplotype frequencies inference based on a joint constrained sparse representation of pooled DNA. BMC Bioinformatics. 14(1):270. Go to Pubmed
Jacunski A, Tatonetti N.  2013.  Connecting the dots: applications of network medicine in pharmacology and disease. Clin Pharmacol Ther. 94(6):659-69. Go to Pubmed
Basu A, Bodycombe NE, Cheah JH, Price EV, Liu K, Schaefer GI, Ebright RY, Stewart ML, Ito D, Wang S et al.  2013.  An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules. Cell. 154(5):1151-61. Go to Pubmed
Tavazoie S.  2013.  Synaptic state matching: a dynamical architecture for predictive internal representation and feature detection. PLoS One. 8(8):e72865. Go to Pubmed
Ying CY, Dominguez-Sola D, Fabi M, Lorenz IC, Hussein S, Bansal M, Califano A, Pasqualucci L, Basso K, Dalla-Favera R.  2013.  MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma. Nat Immunol. Go to Pubmed
Tarca AL, Lauria M, Unger M, Bilal E, Boue S, Dey KKumar, Hoeng J, Koeppl H, Martin F, Meyer P et al.  2013.  Strengths and limitations of microarray-based phenotype prediction: lessons learned from the IMPROVER Diagnostic Signature Challenge. Bioinformatics. 29(22):2892-9. Go to Pubmed
Sun J, Keim CD, Wang J, Kazadi D, Oliver PM, Rabadan R, Basu U.  2013.  E3-ubiquitin ligase Nedd4 determines the fate of AID-associated RNA polymerase II in B cells. Genes Dev. 27(16):1821-33. Go to Pubmed
Meyer P, Siwo G, Zeevi D, Sharon E, Norel R, Segal E, Stolovitzky G.  2013.  Inferring gene expression from ribosomal promoter sequences, a crowdsourcing approach. Genome Res. 23(11):1928-37. Go to Pubmed
Antebi YE, Reich-Zeliger S, Hart Y, Mayo A, Eizenberg I, Rimer J, Putheti P, Pe'er D, Friedman N.  2013.  Mapping differentiation under mixed culture conditions reveals a tunable continuum of T cell fates. PLoS Biol. 11(7):e1001616. Go to Pubmed
Aytes A, Mitrofanova A, Kinkade CWaugh, Lefebvre C, Lei M, Phelan V, H Lekaye C, Koutcher JA, Cardiff RD, Califano A et al.  2013.  ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer. Proc Natl Acad Sci U S A. Go to Pubmed
Frattini V, Trifonov V, Chan JMinhow, Castano A, Lia M, Abate F, Keir ST, Ji AX, Zoppoli P, Niola F et al.  2013.  The integrated landscape of driver genomic alterations in glioblastoma. Nat Genet. Go to Pubmed
Tepper RG, Ashraf J, Kaletsky R, Kleemann G, Murphy CT, Bussemaker H.  2013.  PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity. Cell. 154(3):676-90. Go to Pubmed
Perez-Garcia A, Ambesi-Impiombato A, Hadler M, Rigo I, Leduc CA, Kelly K, Jalas C, Paietta E, Racevskis J, Rowe JM et al.  2013.  Genetic loss of SH2B3 in acute lymphoblastic leukemia. Blood. Go to Pubmed
Rudchenko M, Taylor S, Pallavi P, Dechkovskaia A, Khan S, Butler VP, Rudchenko S, Stojanovic MN.  2013.  Autonomous molecular cascades for evaluation of cell surfaces. Nat Nanotechnol. 8(8):580-6. Go to Pubmed
Piana S, Lindorff-Larsen K, Shaw DE.  2013.  Atomistic description of the folding of a dimeric protein. J Phys Chem B. Go to Pubmed
Arkhipov A, Shan Y, Kim ET, Dror RO, Shaw DE.  2013.  Her2 activation mechanism reflects evolutionary preservation of asymmetric ectodomain dimers in the human EGFR family. Elife. 2:e00708. Go to Pubmed
Tatonetti N, Denny JC, Altman R.  2013.  Response to 'Use of an algorithm for identifying hidden drug-drug interactions in adverse event reports' by Gooden et al. J Am Med Inform Assoc. 20(3):591. Go to Pubmed
Hottes AK, Freddolino PL, Khare A, Donnell ZN, Liu JC, Tavazoie S.  2013.  Bacterial adaptation through loss of function. PLoS Genet. 9(7):e1003617. Go to Pubmed
Chiu IM, Morimoto ETA, Goodarzi H, Liao JT, O'Keeffe S, Phatnani HP, Muratet M, Carroll MC, Levy S, Tavazoie S et al.  2013.  A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model. Cell Rep. 4(2):385-401. Go to Pubmed
Kreimer A, Pe'er I.  2013.  Variants in exons and in transcription factors affect gene expression in trans. Genome Biol. 14(7):R71. Go to Pubmed
Eastwood MP, Chitra T, Jumper J, Palmo K, Pan AC, Shaw DE.  2013.  Rotational relaxation in ortho-terphenyl: using atomistic simulations to bridge theory and experiment. J Phys Chem B. Go to Pubmed
Jing C, Cornish VW.  2013.  Design, synthesis, and application of the trimethoprim-based chemical tag for live-cell imaging. Curr Protoc Chem Biol. 5(2):131-55. Go to Pubmed
Daneshjou R, Tatonetti N, Karczewski KJ, Sagreiya H, Bourgeois S, Drozda K, Burmester JK, Tsunoda T, Nakamura Y, Kubo M et al.  2013.  Pathway analysis of genome-wide data improves warfarin dose prediction. BMC Genomics. 14 Suppl 3:S11. Go to Pubmed
Kobayashi T, Wang J, Al-Ahmadie HA, Abate-Shen C.  2013.  ARF regulates the stability of p16 protein via REGγ-dependent proteasome degradation. Mol Cancer Res. Go to Pubmed
de Julio MKruithof-, Shibata M, Desai N, Reynon M, M Halili V, Hu Y-P, Price SM, Abate-Shen C, Shen MM.  2013.  Canonical Wnt signaling regulates Nkx3.1 expression and luminal epithelial differentiation during prostate organogenesis. Dev Dyn. Go to Pubmed
Palamara PFrancesco, Pe'er I.  2013.  Inference of historical migration rates via haplotype sharing. Bioinformatics. 29(13):i180-i188. Go to Pubmed