Nicholas Tatonetti

Nicholas Tatonetti


Herbert Irving Assistant Professor of Biomedical Informatics
Director of Clinical Informatics, Herbert Irving Comprehensive Cancer Center


Department of Systems Biology
Center for Computational Biology and Bioinformatics
Department of Medicine
Department of Biomedical Informatics
Center for Cancer Systems Therapeutics


(212) 305-2055

Nicholas Tatonetti is an assistant professor in the Department of Biomedical Informatics. He is developing methods for integrating and analyzing heterogeneous data types, including next-generation genome and transcriptome sequencing, metabolomics, proteomics, and electronic medical records. He and members of his laboratory develop algorithms and methods based on rigorous computational and mathematical approaches that can be used to account for the lack of controls within large, heterogenous data sets. The goals of his research are to understand basic biology, and ultimately to use this knowledge to improve human health.

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Electronic Health Record Analysis Shows Which Diseases Run in Families
Findings from a new study by researchers at Columbia University Irving Medical Center and NewYork-Presbyterian could streamline efforts to understand and mitigate disease risk—especially for diseases with no known disease-associated genes. The study, published by Cell, was co-led by Systems Biology’s Nicholas Tatonetti, PhD, and David Vawdrey, PhD, of Biomedical Informatics.
From Code to Cure
The cover story of Columbia Magazine's Spring 2018 issue spotlights how Columbia University researchers, including Systems Biology faculty Andrea Califano, Dr, and Nicholas Tatonetti, PhD, are rewriting the rules of medical research in the age of data science. This new era also is providing opportunities to study the world in entirely new ways. Nowhere is this more evident than in medicine.
Tatonetti Named Director of Clinical Informatics at Institute for Genomic Medicine
As director of clinical informatics at Columbia's Institute for Genomic Medicine, Dr. Nicholas Tatonetti leads the organizing, directing and evaluating of all clinical informatics efforts across the Institute, with particular attention on the integration of electronic health record data for use in genetics and genomics studies.
Columbia Scientists Receive Grant to Integrate Clinical and Molecular Data
Medical doctors and basic scientists tend to speak about human health in different languages. A project called DeepLink aims to provide a way to translate knowledge across multiple scales.
Columbia Awarded NCI Center for Cancer Systems Biology
The Center for Cancer Systems Therapeutics (CaST) is developing a framework that can account for the dynamic nature of cancer and use this knowledge to disrupt the programs that maintain tumor survival.