Nicholas Tatonetti

Nicholas Tatonetti


Associate Professor of Biomedical Informatics (in Systems Biology and in Medicine)


Department of Systems Biology
Center for Computational Biology and Bioinformatics
Department of Medicine
Department of Biomedical Informatics
Center for Cancer Systems Therapeutics


(212) 305-2055

Nicholas Tatonetti is an associate professor in the Department of Biomedical Informatics. He is developing methods for integrating and analyzing heterogeneous data types, including next-generation genome and transcriptome sequencing, metabolomics, proteomics, and electronic medical records. He and members of his laboratory develop algorithms and methods based on rigorous computational and mathematical approaches that can be used to account for the lack of controls within large, heterogenous data sets. The goals of his research are to understand basic biology, and ultimately to use this knowledge to improve human health.

More News


Ancient Part of Immune System May Underpin Severe COVID
One of the immune system’s oldest branches, called complement, may be influencing the severity of COVID disease, according to a new study in Nature Medicine led by Drs. Sagi Shapira and Nicholas Tatonetti of the Department of Systems Biology.
New COVID-19 Pilot Grants Awarded to Systems Biology Faculty
Drs. Sagi Shapira and Nicholas Tatonetti, faculty in the Department of Systems Biology, have been awarded a new pilot grant for research geared toward understanding the novel SARS-CoV-2 virus.
Nicholas Tatonetti, PhD: Always Thinking Outside the Box
Nicholas Tatonetti solves problems. He has always enjoyed it, and as the informatics community has discovered, he is both creative and proficient in his methods. Awarded tenure this year and promoted to associate professor, Dr. Tatonetti focuses on the use of advanced data science methods, including AI and machine learning, to investigate medicine safety. Learn more about Dr. Tatonetti and his innovative research in this recent faculty profile.
Newly Tenured Systems Biology Faculty
Congratulations to Drs. Yufeng Shen, Nicholas Tatonetti, and Chaolin Zhang of the Department of Systems Biology, who have been awarded tenure and promoted to associate professor. Their new appointments are effective July 1, 2019.
Columbia Highlights MD/PhD Student Research
Congratulations to Phyllis Thangaraj, an MD/PhD student in the Nicholas Tatonetti lab, for her winning poster session at an event recognizing aspiring physician-scientists from the Vagelos College of Physicians and Surgeons. Students in the MD/PhD program training program at Columbia University Irving Medical Center presented their research posters at the 14th annual Student Research Symposium on April 25, and topics included a wide range, such as Alzheimer’s disease, stroke, and stem cells. Thangaraj discussed ongoing research in applying machine learning methods to phenotype acute ischemic stroke patients in electronic health records.