Graduate Student, Cellular, Molecular and Biophysical Studies
As a graduate student in the lab of Virginia Cornish, I am interested in developing new technologies and applications in the field of metabolic engineering. Specifically, my projects involve using yeast as a factory for the production of therapeutic compounds.
Prior to working at the Cornish lab, I obtained my bachelor’s degree in chemistry from the Universidad Nacional de Ingenieria in Peru, where I also worked in the labs of Victor Reyna on characterizing alkaloids from Peruvian plants and Mirko Zimic on computational study of metalloproteins. After college, I worked in Elsa Yan’s lab at the Chemistry Department at Yale University, where I used biophysical techniques to study the thermostability of rhodopsin and its implications in retinal degeneration.
Ng, YZ, Baldera-Aguayo PA, Cornish, VW. Fluorescence polarization assay for small molecule screening of FK506 biosynthesized in 96-well microtiter plates. Biochemistry. 2017 Sept 21; 10.1021/acs.biochem.7b00602.
Berthelot K, Estevez Y, Quiliano M, Baldera-Aguayo PA, Zimic M, Pribat A, Bakleh ME, Teyssier E, Gallusci P, Gardrat C, Lecomte S, Peruch F. HbIDI, SlIDI and EcIDI: A comparative study of isopentenyl diphosphate isomerase activity and structure. Biochimie. 2016 Aug;127:133-43.
Salazar-Salinas K, Baldera-Aguayo PA, Encomendero-Risco JJ, Orihuela M, Sheen P, Seminario JM, Zimic M. Metal-ion effects on the polarization of metal-bound water and infrared vibrational modes of the coordinated metal center of Mycobacterium tuberculosis pyrazinamidase via quantum mechanical calculations. J Phys Chem B. 2014 Aug 28;118(34):10065-75.
Liu MY, Liu J, Mehrotra D, Liu Y, Guo Y, Baldera-Aguayo PA, Mooney VL, Nour AM, Yan EC. Thermal stability of rhodopsin and progression of retinitis pigmentosa: comparison of S186W and D190N rhodopsin mutants. J Biol Chem. 2013 Jun 14;288(24):17698-712.