The Columbia University Department of Systems Biology brings together researchers specializing in computational biology, experimental biology, and technology development to discover how biological traits emerge from complex molecular networks.
Systems biology and computational biology are becoming increasingly important disciplines in the biological sciences. Through PhD graduate education and postdoctoral training we prepare young scientists to become leaders in this exciting and rapidly growing field.
AnnouncementDepartment of Systems Biology Opens New Biotechnology Development Hub
The new space will promote the design of new experimental methods for studying biological systems, and enable an expansion of the Columbia Genome Center's next-generation sequencing capabilities.
Awards and GrantsAndrea Califano Named NCI Outstanding Investigator
The seven-year grant will support the development of systematic approaches for identifying the molecular factors that lead to cancer progression and to the emergence of drug resistance at the single-cell level.
EducationColumbia Launches Undergraduate Synthetic Biology Team
For this year’s International Genetically Engineered Machine Foundation (iGEM) competition, the team used synthetic biology methods to engineer edible probiotic bacteria that could regulate hunger and digestion.
AnnouncementFaculty Members Join Department of Systems Biology and C2B2
Kam Leong (Biomedical Engineering) has joined the Department as an interdisciplinary faculty member, while Yaniv Erlich (Computer Science) and Guy Sella (Biological Sciences) bring new expertise to C2B2.
EducationGraduate Course Focuses on Foundations of Deep Sequencing
The new team-taught course provides an understanding of both the experimental principles of next-generation sequencing technologies and key statistical methods for analyzing the data they produce.
Upcoming EventsDepartment of Systems Biology Announces 2015-2016 Seminar Series
This year's visiting speakers series will include Anshul Kundaje, Nevan Krogan, Sarah Tishkoff, Jef Boeke, and others. Click on the link above for the complete schedule, and mark your calendars!
Research NewsPromising New Targets for Treating HER2-Positive Breast Cancer
Systems biology approaches have identified a signaling pathway responsible for a subtype of aggressive breast cancer, as well as FDA-approved drugs capable of targeting it. A clinical trial is now underway to test the findings.
Awards and GrantsSaeed Tavazoie Wins Transformative Research Award
With the support of the NIH’s High-Risk, High-Reward Research program, Tavazoie will develop a new technology combining experimental and computational methods to map all pairwise molecular interactions in the cell.
In the PressKyle Allison Featured in NIH Director’s Blog
A post authored by NIH Director Francis Collins highlights Dr. Allison’s ongoing efforts to isolate and study "persistent" bacteria, which in the clinic can often instigate dangerous, chronic infections that are difficult to eliminate.
EducationPutting Blended Learning to the Test
Electronic media offer valuable tools for learning, but what is the best way to integrate such technologies within the traditional university setting? Brent and Melissa Stockwell recently conducted an innovative, formal trial to find out.
Awards and GrantsOliver Hobert Named Javits Neuroscience Investigator
This prestigious grant supports investigators who have demonstrated exceptional achievement throughout their careers. It will enable the Hobert Lab to investigate sex-based differences in the regulation of neuronal identity.
EducationRNA-Seq "Boot Camp" Resources Now Available
In June 2015, a five-part lecture series organized by the Department of Systems Biology covered new applications of RNA-Seq and methods for more effective data analysis. Click the link for lecture notes and other related information.
Events and Seminars
November 30, 2015 - 12:00pm to 3:00pm
(American Museum of Natural History)▶ More information
December 3, 2015 - 3:00pm
Long Cai(California Institute of Technology)