The Columbia University Department of Systems Biology brings together researchers specializing in computational biology, experimental biology, and technology development to discover how biological traits emerge from complex molecular networks.
Systems biology and computational biology are becoming increasingly important disciplines in the biological sciences. Through PhD graduate education and postdoctoral training we prepare young scientists to become leaders in this exciting and rapidly growing field.
Spotlighting Interdisciplinary Research and Young Investigators
Innovative research projects were highlighted at the Department of Systems Biology’s annual retreat at Wave Hill Public Garden and Cultural Center. The retreat, attended by 160 guests, also provided an opportunity for young investigators to showcase their work during a poster competition. Congratulations goes out to this year's research poster winners: Andy Chiang (Vitkup Lab), Huijuan Feng (Zhang Lab) and Hanna Levitin (Sims Lab).
Dr. Andrea Califano Named to the National Academy of Medicine
Congratulations to Department Chair Dr. Andrea Califano for his election today in the National Academy of Medicine, one of the highest honors in health and medicine. A pioneer in systems biology, Dr. Califano has directed the conversation about cancer research away from focusing solely on gene mutations, and examines the complex and tumor-specific molecular interaction networks that determine cancer cell behavior.
ProfileQ+A with Dr. Laura Landweber
Laura Landweber, PhD, loves a challenge. So it’s no surprise that she has built a scientific career unraveling the hows and whys of a unique single-cell organism known for its biological complexity. Oxytricha trifallax is a microbial organism that is prevalent in ponds, feeds on algae and has a highly complex genome architecture, making it an attractive, albeit challenging, model organism to study. Several of the basic biology discoveries made in Oxytricha have been shown to extend to other organisms.
Research NewsStress Wracks Worm Nerves, Leaving Lasting Memories
In a new study, led by Professor Oliver Hobert, PhD, scientists stunted the puberty of male worms by starving them before they underwent sexual maturation. The study, published in Nature, suggested that stress from starvation even days before sexual maturation prevented normal changes in the wiring patterns of key neuronal circuits, which caused adult male worms to act immature.
EducationPhD Candidate Brian Ji Wins for Outstanding Research at Integrated Conference
Brian Ji, an MD/PhD student in systems biology and a member of the Vitkup Lab, delivered the winning talk at the Biennial Integrated Program Retreat. Ji, who discussed a novel experimental and computational method to understand spatiotemporal dynamics of the human gut microbiome, was one of six systems biology students who delivered research presentations at the conference.
Events and Seminars
October 23, 2018 - 5:00pm
Dr. Tuuli Lappalainen
November 8, 2018 - 5:00pm
Dr. Yufeng Shen
November 13, 2018 - 5:00pm
Dr. Saeed Tavazoie