Research
The Columbia University Department of Systems Biology brings together researchers specializing in computational biology, experimental biology, and technology development to discover how biological traits emerge from complex molecular networks.
Education
Systems biology and computational biology are becoming increasingly important disciplines in the biological sciences. Through PhD graduate education and postdoctoral training we prepare young scientists to become leaders in this exciting and rapidly growing field.
- Graduate Education
- Postdoctoral Training
Infrastructure
Our core facilities include centers for next-generation sequencing and high-throughput screening, as well as a high-performance computing center dedicated to research in molecular and systems biology.
- Columbia Genome Center
- Advanced Research Computing

News

From Renaissance to Research: Columbia’s DREAM-High Program Brings Cancer Genomics Research to High School Students

When Diana Murray first started working with two high school students on an online summer cancer systems biology course in 2018, she never imagined that the initiative, now called DREAM-High, would snowball to 56 participants by 2026. “The class started as a consolation prize for high school students who didn’t get selected for a different program funded by the Palazzo Strozzi Foundation,” shares Murray, who in addition to being a computational systems biologist is also the Program Director of Research and Education at Columbia University. And she proceeds to explain.

Awards and Grants

Mohammed AlQuraishi, PhD receives grant from the National Library of Medicine

Mohammed AlQuraishi, PhD will receive $1,440,905 over four years from the National Library of Medicine for “Fast and slow prediction of stable and transient protein-protein interactions.”

Awards and Grants

Harris Wang, PhD receives grant from National Science Foundation

Harris Wang, PhD will receive $914,479 over three years from the National Science Foundation for “Elucidating principles of microbiome spatial organization using synthetic gut communities.”

Awards and Grants

Chaolin Zhang, PhD and Dian Yang, PhD among 12 VP&S Scientists Awarded Schaefer Scholar Grants

Chaolin Zhang, PhD and Dian Yang, PhD are among twelve scientists at Columbia University Vagelos College of Physicians and Surgeons have received awards from the Schaefer Research Scholars Program, made possible through a bequest from Dr. Ludwig Schaefer.

Please access full article here.

In the Press

Mohammed AlQuraishi, PhD and collaborators developed ROCKET

ROCKET, developed by Mohammed AlQuraishi and collaborators, is a post-AlphaFold tool that uses experimental data to refine dynamic protein structures.

Please access full article here.