The Columbia University Department of Systems Biology brings together researchers specializing in computational biology, experimental biology, and technology development to discover how biological traits emerge from complex molecular networks.
Systems biology and computational biology are becoming increasingly important disciplines in the biological sciences. Through PhD graduate education and postdoctoral training we prepare young scientists to become leaders in this exciting and rapidly growing field.
Precision Oncology: New Tests Look Beyond Genes
Two new precision medicine tests, born out of research from the Califano Lab, have just received New York State Department of Health approval and are available to oncologists and cancer researchers for the front lines of patient care.
Research Unveils a Developmental Splicing Program Controlling Neuronal Maturation and Excitability
In a new study, Professors Chaolin Zhang and Hynek Wichterle determined that loss of Rbfox genes results in an “embryonic like” splicing program. They observed a significant disruption of the assembly of the axon initial segment, which is key for clustering of ion channels, and thus, for neurons to fire action potentials.
Symposium to Spotlight Advancements in Translational Cancer Research
February 7-8 Cancer Genomics and Mathematical Data Analysis Symposium to feature talks by leading computational biologists, physicists, engineers, mathematicians, and oncologists. Registration required and conference to be held at Heart Conference Center, Columbia University Medical Center.
Integrating Single-Cell Sequencing with Live Cell Imaging
Jointly awarded a $1.5 million NIH grant, the Sims Lab and Cell Microsystems are collaborating to build and test a novel single-cell analysis platform that enables live cell imaging on a large scale and at low cost.
Novel Precision Medicine Trial for Metastatic Pancreatic Cancer
Herbert Irving Comprehensive Cancer Center and Systems Biology have been awarded a three-year grant from the Lustgarten Foundation to test a new precision medicine approach aimed at metastatic pancreatic cancer.
Events and Seminars
February 26, 2018 - 11:00am
Emily Marcinkevicius, PhD(Nature Genetics)
March 1, 2018 - 11:00am
Hatice Ulku Osmanbeyoglu, PhD(Memorial Sloan Kettering Cancer Center)