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Research Unveils a Developmental Splicing Program Controlling Neuronal Maturation and Excitability
In a new study, Professors Chaolin Zhang and Hynek Wichterle determined that loss of Rbfox genes results in an “embryonic like” splicing program. They observed a significant disruption of the assembly of the axon initial segment, which is key for clustering of ion channels, and thus, for neurons to fire action potentials.
Symposium to Spotlight Advancements in Translational Cancer Research
February 7-8 Cancer Genomics and Mathematical Data Analysis Symposium to feature talks by leading computational biologists, physicists, engineers, mathematicians, and oncologists. Registration required and conference to be held at Heart Conference Center, Columbia University Medical Center.
Integrating Single-Cell Sequencing with Live Cell Imaging
Jointly awarded a $1.5 million NIH grant, the Sims Lab and Cell Microsystems are collaborating to build and test a novel single-cell analysis platform that enables live cell imaging on a large scale and at low cost.
Novel Precision Medicine Trial for Metastatic Pancreatic Cancer
Herbert Irving Comprehensive Cancer Center and Systems Biology have been awarded a three-year grant from the Lustgarten Foundation to test a new precision medicine approach aimed at metastatic pancreatic cancer.
Tatonetti Named Director of Clinical Informatics at Institute for Genomic Medicine
As director of clinical informatics at Columbia's Institute for Genomic Medicine, Dr. Nicholas Tatonetti leads the organizing, directing and evaluating of all clinical informatics efforts across the Institute, with particular attention on the integration of electronic health record data for use in genetics and genomics studies.