The Columbia University Department of Systems Biology brings together researchers specializing in computational biology, experimental biology, and technology development to discover how biological traits emerge from complex molecular networks.
Systems biology and computational biology are becoming increasingly important disciplines in the biological sciences. Through PhD graduate education and postdoctoral training we prepare young scientists to become leaders in this exciting and rapidly growing field.
Research NewsDynamics of Gut Bacteria Follow Ecological Laws
The seemingly chaotic bacterial soup of the gut microbiome is more organized than it first appears and follows some of the same ecological laws that apply to birds, fish, tropical rainforests, and even complex economic and financial markets, according to a new paper in Nature Microbiology by systems biologists at Columbia University Irving Medical Center.
AnnouncementMolly Przeworski, PhD, Elected to the National Academy of Sciences
The National Academy of Sciences (NAS) has elected Molly Przeworski, PhD, to its 2020 class of new members. Election to the NAS is highly prestigious and recognizes members for their distinguished and continuing achievements in original research. Congratulations to Dr. Przeworski!
AnnouncementColumbia's Coronavirus Resource Center
Clinicians and researchers at the Columbia University Irving Medical Center are global leaders in responding to COVID-19. In addition to being at the forefront of the clinical and scientific response to the virus, CUIMC is committed to keeping patients and the CUIMC community informed about COVID-19. Information is updated throughout each day as the impact of the virus changes locally and nationally.
ProfileDecoding and Targeting RNA with CRISPR
Xuebing Wu, PhD, joined the Department of Systems Biology in the fall of 2018, with a joint appointment in the Department of Medicine’s Cardiology Division. He also is a member of the Herbert Irving Comprehensive Cancer Center at NewYork-Presbyterian/Columbia and the Data Science Institute, and his lab straddles basic science and computational biology. In this faculty Q+A, we learn how the Wu lab is making an impact in novel therapeutics. At the center of Dr. Wu's research interests is understanding the fundamental principles of gene regulation in human cells through integrative genomics approaches.
In the PressA Systems Biology Approach to Target Pancreatic Cancer
Andrea Califano, Dr, chair of the Department of Systems Biology, has been featured in the “Promising Science” column of “Let’s Win! Pancreatic Cancer”. Dr. Califano discusses how systems biology is being used in cancer research in the development of better treatments by precisely targeting proteins called master regulators, instead of mutations. “I’m a systems biologist and we look at things differently than traditional biologists,” he says. “With systems biology we want to take cancer apart and see how it works, and the only way we can do that is by developing accurate computational models of how the cancer cell works.”
Events and Seminars
May 27, 2020 - 3:00pm
Anjali Hinch, PhD(Oxford University)
April 23, 2020 - 1:30pm
Mikael Vejdemo-Johansson, Dr.rer.nat(CUNY Staten Island)