The Columbia University Department of Systems Biology brings together researchers specializing in computational biology, experimental biology, and technology development to discover how biological traits emerge from complex molecular networks.
Systems biology and computational biology are becoming increasingly important disciplines in the biological sciences. Through PhD graduate education and postdoctoral training we prepare young scientists to become leaders in this exciting and rapidly growing field.
EducationPhD Candidate Brian Ji Wins for Outstanding Research at Integrated Conference
Brian Ji, an MD/PhD student in systems biology and a member of the Vitkup Lab, delivered the winning talk at the Biennial Integrated Program Retreat. Ji, who discussed a novel experimental and computational method to understand spatiotemporal dynamics of the human gut microbiome, was one of six systems biology students who delivered research presentations at the conference.
Research NewsNew Study Explains Why Genetic Mutations Cause Disease in Some People but Not in Others
A new study, led by Dr. Tuuli Lappalainen, has unveiled a molecular mechanism behind one of biology’s longstanding mysteries: why individuals carrying identical gene mutations for a disease end up having varying severity or symptoms of the disease. In this phenomenon, called variable penetrance, the severity of the effect of disease-causing variants differs among individuals who carry them.
Awards and GrantsPostdoc Suying Bao Named Precision Medicine Fellow
Congratulations to Suying Bao, postdoctoral research scientist in the Chaolin Zhang lab, for recently being named an inaugural Precision Medicine Research fellow by Columbia’s Irving Institute of Clinical and Translational Research. The two-year fellowship aims to train postdocs to use genomics and complex clinical data to improve personalized and tailored clinical care and clinical outcomes.
Awards and GrantsHyundai Awards Columbia $2.5M Grant for Pediatric Cancer Research
A team of researchers at Columbia University Irving Medical Center has recently been awarded a five-year $2.5 million grant from Hyundai Hope on Wheels to fund innovative pediatric cancer research, focusing on childhood cancers with poor prognosis. At Columbia, the team will target osteosarcoma, the most commonly diagnosed bone tumor in children and adolescents.
Awards and GrantsMichael Shen Wins Cancer Research Innovation Award
The Bladder Cancer Advocacy Network has awarded Professor Michael Shen, PhD, the 2018 Bladder Cancer Research Innovation Award. The honor singles out scientists whose creative, novel research has great potential to advance therapies for bladder cancer, the fifth most common cancer in the U.S.
Events and Seminars
September 25, 2018 - 5:00pm
Dr. Rodney Rothstein
September 26, 2018 - 3:00pm
Dr. Ken Chen(MD Anderson Cancer Center)
October 2, 2018 - 5:00pm
Dr. Yufeng Shen