News

A discussion with Andrea Califano(link is external and opens in a new window) and narrative medicine writer Rita Charon, "Aflight in ideas and visions, he and his colleagues in systems biology have been soaring toward what Califano predicts as the Golden Age of Biology. Not unlike the golden ages of physics and chemistry, when Newton and Lavoisier broke through conceptual barriers to see with new minds, this age equips biology for flight"

Read full article on Narratives of Discovery page.

December 14, 2021

New award for Chaolin Zhang

Chaolin Zhang, PhD, Associate Professor in Systems Biology will receive $2,766,392 over five years from the National Insititue of Neurological Disorders and Stroke for “RNA regulatory networks in neuronal cell type diversity and function”. This award will support Dr. Zhang to understand better post-transcriptional gene expression regulation through specific protein -RNA interactions, or RNA-regulatory networks which is critical for expanding the complexity of the mammalian nervous system with implications in an expanding list of neuronal disorders. The proposed studies will investigate alternative splicing regulation in generating the distinct molecular programs in diverse neuronal cell types of mouse cortex. Information obtained in this project will provide insights into the fundamental mechanisms that controls such diversity as well as the functional consequences in defined, clinically relevant neuronal cell types.

Chaolin Zhang, PhD, Associate Professor in Systems Biology will receive $1,200,000 over three years from The Simons Foundation Autism Research Initiative (SFARI) via the 2021 Genomics of ASD: Pathways to Genetic Therapies Initiative.  Grants funded through this Initiative are intended to leverage current knowledge about risk genes for autism spectrum disorder (ASD) into the development of new genetic therapies.  Leveraging the target discovery platform developed by the lab, Dr. Zhang’s research goal on this project focuses on restoring functional protein production using antisense oligos (ASOs) by modulating the alternative splicing as potential therapeutics. 

Read full article on Simons Foundation website.

Honoring outstanding postdoctoral scientists from academic research institutions across New York, New Jersey, and Connecticut, the Blavatnik Family Foundation and the New York Academy of Sciences announced the three Winners and six Finalists of the 2021 Blavatnik Regional Awards for Young Scientists. 

Biologists aspire to understand every gene’s contribution to an organism’s biology and behavior. Microbiologist Wenyan Jiang has helped repurpose the CRISPR-Cas system, an immune system of many bacteria, and co-opt it to upgrade the way many scientists control and examine the genome. Jiang developed a groundbreaking tool called CRISPR Adaptation-mediated Library Manufacturing (CALM), which exploits CRISPR RNA, a type of RNA naturally found in bacteria. CALM has enabled scientists to quickly determine the causal link between genes and bacterial behaviors such as antibiotic resistance and pathogenesis and pave the way for developing new, effective antimicrobial drugs. 

Read full article on Blavatnik Award site

September 10, 2021

New award for Harris Wang

Harris Wang receives the Vilcek Prize for Creative Promise in Biomedical Science for the development and application of Multiplex Automated Genome Engineering (MAGE), a new framework for manipulating DNA to produce synthetic or engineered recombinant genetic material, and for his use of CRISPR technology to track and record transient cellular processes in the human gut microbiome. Born in Beijing, China, Wang is an associate professor at Columbia University in New York.

The 2022 Vilcek Foundation Prizes in Biomedical Science are a part of the Vilcek Foundation Prizes program. In 2022, the foundation is awarding the Vilcek Foundation Prizes in Biomedical Science, the Vilcek Foundation Prizes in Dance, and the Vilcek Prize for Excellence.

See full article on Vilcek Foundation site.