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Haemoglobin content of multilayer E rosettes is a parameter of activated human T lymphocytes..
Clinical and experimental immunology.
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Reciprocal connections between the lateral hypothalamus and the frontal complex in the rat: electrophysiological and anatomical observations..
Brain research.
213
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. 2026.
Multiple molecular and cellular properties jointly affect protein and site-specific evolutionary rates..
bioRxiv : the preprint server for biology.
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. 2026.
Onconeural antigen NOVA1 dysregulates RNA alternative splicing in breast cancer..
RNA (New York, N.Y.).
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. 2026.
A forward genetic screen identifies Sirtuin1 as a driver of neuroendocrine prostate cancer..
The Journal of experimental medicine.
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. 2026.
Paired Tumor Biopsies Reveal Spatiotemporal Myeloid Remodeling After Local Chemotherapy in Glioblastoma..
bioRxiv : the preprint server for biology.
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Foundation models and deep learning for cancer drug response prediction: a framework for data, metrics, and validation..
Briefings in bioinformatics.
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. 2026.
Fast and Ultra-Capable Protein Design: Advancing the Frontier Through Atomistic SE(3)-Equivariance with Genie 3..
bioRxiv : the preprint server for biology.
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. 2026.
Modeling patient variants of and results in distinct forms of congenital diaphragmatic hernia in mice..
bioRxiv : the preprint server for biology.
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. 2026.
The genetic landscape of antibiotic sensitivity in ..
Science advances.
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. 2026.
A functional investigation of antibody Fc-FcRn variant binding guided by free energy perturbation methods..
bioRxiv : the preprint server for biology.
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. 2026.
Toward life with a 19-amino acid alphabet through generative artificial intelligence design..
Science (New York, N.Y.).
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. 2026.
Molecular dynamics simulations of intrinsically disordered protein regions enable biophysical interpretation of variant-effect predictors..
HGG advances.
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. 2026.
Systematic design of combination therapy by targeting master regulators of coexisting diffuse midline glioma cell states..
Nature genetics.
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. 2026.
Reply to Du: Differences in experimental setting make validation harder..
American journal of obstetrics & gynecology MFM.
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. 2026.
End-to-end evaluation of pipelines for metagenome-assembled genomes reveals hidden performance gaps..
bioRxiv : the preprint server for biology.
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. 2026.
Combining structural modeling and deep learning to calculate the E. coli protein interactome and functional networks..
Nature communications.
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. 2026.
GREmLN: A Cellular Graph Structure Aware Transcriptomics Foundation Model..
bioRxiv : the preprint server for biology.
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. 2026.
Proteome-wide prediction of interactions between structured domains and peptide motifs reveals functionally coherent subnetworks..
Proceedings of the National Academy of Sciences of the United States of America.
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. 2026.
AlphaFold as a prior: experimental structure determination conditioned on a pretrained neural network..
Nature methods.
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. 2026.
Exon inclusion signatures enable accurate estimation of splicing factor activity..
Nature communications.
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. 2026.
Exon inclusion signatures enable accurate estimation of splicing factor activity..
Nature communications.
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. 2026.
Dissociable perfusion chip (DPC): perfusable microfluidic chip for single-cell screening of anti-cancer drugs in live glioblastoma explants..
Lab on a chip.
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. 2026.
PrePPI - Structure-based Prediction of Protein-protein Interactomes and Networks..
Journal of molecular biology.
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. 2026.
A generalizable cross-continent prediction of esophageal squamous cell carcinoma using the oral microbiome..
Communications medicine.
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Single-cell RNA sequencing of adenoid cystic carcinoma of the breast reveals cellular heterogeneity and tumor microenvironment features..
BMC medical genomics.
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Neoadjuvant Fc-enhanced anti-CTLA-4 targets Tregs to augment androgen deprivation in high-risk prostate cancer: A randomized phase I trial..
Cell reports. Medicine.
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. 2026.
CLADES - Contrastive Learning Augmented DifferEntial Splicing with Orthologous Positive Pairs..
bioRxiv : the preprint server for biology.
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. 2026.
A neuron type-specific microexon in Ank3/ankyrin-G modulates calcium activity and neuronal excitability..
Nature communications.
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. 2026.
A neuron type-specific microexon in Ank3/ankyrin-G modulates calcium activity and neuronal excitability..
Nature communications.
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. 2026.
IDH-mutant inhibitors enhance the sensitivity of IDH1-mutant gliomas to cysteine-methionine deprivation and ferroptosis..
bioRxiv : the preprint server for biology.
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. 2026.
Pan-cancer inference and validation of hypermorphic, hypomorphic and neomorphic mutations..
Nature genetics.
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. 2026.
Topology-Based Biomarkers Accurately Predict Breast Cancer Outcome and Survival..
Cancer research.
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. 2026.
Machine learning to infer neurocognitive testing scores among adolescents and young adults with congenital heart disease..
Communications medicine.
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. 2026.
Publisher Correction: Deciphering the role of complement system genes in pancreatic cancer susceptibility and prognosis..
Nature communications.
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Protein language models trained on biophysical dynamics inform mutation effects..
Proceedings of the National Academy of Sciences of the United States of America.
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MYRF controls mesothelium specification, signaling, and plasticity in lung development..
Developmental cell.
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Mapping kinase-dependent tumor immune adaptation with multiplexed single-cell CRISPR screens..
bioRxiv : the preprint server for biology.
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A transposase-derived gene required for human brain development..
Science advances.
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Visualization and quantification of rDNA instabilities in mammalian cells and mouse models..
Nucleic acids research.
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Antisense oligonucleotides to KIF1A polymorphisms expand targets and rescue patient-derived neurons in vitro..
Nature communications.
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. 2025.
TMPO promotes cellular dissemination and metastasis in circulating tumor cells..
bioRxiv : the preprint server for biology.
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. 2025.
TMPO promotes cellular dissemination and metastasis in circulating tumor cells..
bioRxiv : the preprint server for biology.
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. 2026.
Mapping isoforms and regulatory mechanisms from spatial transcriptomics data with SPLISOSM..
Nature biotechnology.
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Efficient algorithms for simulating sequences along a phylogenetic tree..
Bioinformatics (Oxford, England).
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. 2025.
Lipidomic changes in persister cancer cells drive enhanced ferroptosis sensitivity..
Ferroptosis and oxidative stress.
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. 2025.
Primate-specific adaptation of Ku protects transcriptomic integrity by suppressing Alu-mediated alternative splicing..
bioRxiv : the preprint server for biology.
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. 2026.
Mismatch repair deficiency drives malignant progression and alters the tumor immune microenvironment in glioblastoma models..
The Journal of clinical investigation.
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. 2025.
A neuron type-specific microexon in /ankyrin-G modulates calcium activity and neuronal excitability..
bioRxiv : the preprint server for biology.
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. 2025.
Determinants of sensitivity to HER2-targeted antibody drug conjugates in urothelial cancer..
Nature communications.
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. 2025.
Comparative metagenomics using pan-metagenomic graphs..
bioRxiv : the preprint server for biology.
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. 2025.
MCSPACE: inferring microbiome spatiotemporal dynamics from high-throughput co-localization data..
Microbiome.
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. 2026.
Tissue signatures of human macrophages during homeostasis and activation..
Journal of immunology (Baltimore, Md. : 1950).
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. 2025.
A generalizable cross-continent prediction of esophageal squamous cell carcinoma using the oral microbiome..
bioRxiv : the preprint server for biology.
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. 2026.
Transcriptomic Plasticity Is a Hallmark of Metastatic Pancreatic Cancer..
Cancer research.
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selectively governs hematopoietic stem cell self-renewal by regulating proteostasis..
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Towards Clinical Translation: Establishing Optimal Dose and Dose-Rate Parameters for the FLASH Skin-Sparing Effect..
Dose-response : a publication of International Hormesis Society.
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. 2025.
Deciphering the role of complement system genes in pancreatic cancer susceptibility and prognosis..
Nature communications.
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Distributional bias compromises leave-one-out cross-validation..
Science advances.
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NSD2 targeting reverses plasticity and drug resistance in prostate cancer..
Nature.
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NSD2 targeting reverses plasticity and drug resistance in prostate cancer..
Nature.
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. 2025.
Colibactin-producing promote carcinogenesis of gastroesophageal adenocarcinoma and simultaneously induce autophagy and differentiation..
bioRxiv : the preprint server for biology.
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. 2025.
Macroecological Laws Can Naturally Arise from Chaotic Internal Species Dynamics..
bioRxiv : the preprint server for biology.
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. 2025.
MotifAE Reveals Functional Sequence Patterns from Protein Language Model: Unsupervised Discovery and Interpretability Analysis..
bioRxiv : the preprint server for biology.
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Molecular Systems Biology at 20: reflecting on the past, envisioning the future..
Molecular systems biology.
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Combinatorial protein engineering identifies potent CRISPR activators with reduced toxicity..
Nature communications.
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Fecal exfoliome sequencing captures immune dynamics of the healthy and inflamed gut..
Nature biotechnology.
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Engineered probiotic restores GLP-1 signaling to ameliorate fiber-deficiency exacerbated colitis..
Science advances.
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TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD..
Nature neuroscience.
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. 2025.
Accurate affinity models for SH2 domains from peptide binding assays and free-energy regression..
Protein science : a publication of the Protein Society.
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Lung tissue-resident memory T cells optimize protection by IL-10 regulation of innate immunity..
The Journal of experimental medicine.
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Lung tissue-resident memory T cells optimize protection by IL-10 regulation of innate immunity..
The Journal of experimental medicine.
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Mitochondrial Lon Peptidase 1 Controls Diaphragm and Lung Development in a Context-Dependent Manner..
Journal of respiratory biology and translational medicine.
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Complex Assembly and Activity States as Multifaceted Protein Attributes Explaining Phenotypic Variability..
bioRxiv : the preprint server for biology.
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. 2025.
Convection-enhanced delivery of dexamethasone in glioma suppresses myeloid inflammation while avoiding systemic toxicities..
bioRxiv : the preprint server for biology.
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. 2025.
Developments and Opportunities in Temperature-Responsive Thermal Smart Materials..
Advanced materials (Deerfield Beach, Fla.).
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. 2025.
Identification of Sample Processing Errors in Microbiome Studies Using Host Genetic Profiles..
bioRxiv : the preprint server for biology.
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Factors Influencing Bile Leakage and Incisional Infection Post Choledocholithotomy: An Analysis Based on 621 Patients..
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes.
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. 2026.
LONP1 Variants Are Associated With Clinically Diverse Phenotypes..
Clinical genetics.
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The Role of Recruited Adipose Stromal Cells and Their Fibroblastic Differentiation in Cancer..
Frontiers in bioscience (Landmark edition).
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Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate..
Developmental cell.
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. 2025.
A Simple data-driven dietary pattern associated with lower risk for adverse pregnancy outcomes..
American journal of obstetrics & gynecology MFM.
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. 2025.
Predicting the DNA binding specificity of transcription factor mutants using family-level biophysically interpretable machine learning..
Nucleic acids research.
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. 2025.
Multimodal learning decodes the global binding landscape of chromatin-associated proteins..
bioRxiv : the preprint server for biology.
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. 2025.
Redefining druggable targets with artificial intelligence..
Nature biotechnology.
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Alpha-synuclein abundance and localization are regulated by the RNA-binding protein PUMILIO1..
Cell reports.
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Multimodal profiling reveals tissue-directed signatures of human immune cells altered with age..
Nature immunology.
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Noise-driven morphogenesis independent of transcriptional regulatory programs..
bioRxiv : the preprint server for biology.
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. 2025.
Transcriptome sequencing of Hodgkin lymphoma Hodgkin and Reed-Sternberg cells reveals escape from NK cell recognition and an unfolded protein response..
bioRxiv : the preprint server for biology.
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. 2025.
Epigenetic targeting of PGBD5-dependent DNA damage in SMARCB1-deficient sarcomas..
The Journal of clinical investigation.
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Understanding Language Model Scaling on Protein Fitness Prediction..
bioRxiv : the preprint server for biology.
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PreMode predicts mode-of-action of missense variants by deep graph representation learning of protein sequence and structural context..
Nature communications.
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