Dana Pe'er

Dana Pe'er


Chair, Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center


Dana Pe’er's lab endeavors to understand the organization, function, and evolution of molecular networks, particularly how variation in DNA sequence alters regulatory networks and leads to the vivid phenotypic diversity of life. Her team develops computational methods that integrate diverse high-throughput data to provide a holistic, systems-level view of molecular networks. She is particularly interested in exploring how systems biology can be used to personalize care for people with cancer. By developing models that can predict how individual tumors will respond to certain drugs and drug combinations, her goal is to develop ways to determine the best drug regime for each patient. Her interest is not only in understanding which molecular components go wrong in cancer cells, but also in using this information to improve cancer therapeutics.

Dr. Pe’er is the recipient of the 2014 Overton Prize, and has been recognized with the Burroughs Wellcome Fund Career Award, an NIH Directors New Innovator Award, an NSF CAREER Award, and a Stand Up To Cancer Innovative Research Grant. She was also named a Packard Fellow in Science and Engineering.

More News


Four Columbia Systems Biology Papers Named among Top Publications
The ISCB/RECOMB Conference on Regulatory and Systems Genomics has announced its top 10 papers of 2014-2015. Four of them involve investigators from the Columbia University Department of Systems Biology.
Method for Analyzing Single-Cell Data Identifies AML Stem Cells
A new algorithm called PhenoGraph revealed a signaling-based signature of this elusive cell type and enabled scientists to define a gene expression signature that is predictive of leukemia patient survival.
Novel Machine Learning Method Expands the Landscape of Breast Cancer Driver Genes
An algorithm by recent PhD graduate Felix Sanchez-Garcia identifies cancer causing genes within somatic copy number alterations, doubling the number of known breast cancer drivers.
Prestigious NIH Director's Awards Go to Two Department of Systems Biology Researchers
Associate Professor Dana Pe’er has received the Pioneer Award for high risk, high reward research, while postdoctoral scientist Kyle Allison has won an Early Independence Award.
Researchers Create Comprehensive Map of Human B Cell Development
A method that uses new single-cell technologies will improve researchers’ ability to investigate development in cells of all types and to identify rare aberrations in development that lead to disease.