Alexander Wang

Overview

Titles

Technician Assistant

Email
aw3436@cumc.columbia.edu

Lab

Andrea Califano

Alec attended Carleton College in Minnesota, where he majored in math and graduated from in 2021. When shadowing physicians, he was particularly impacted by meeting sarcoma patients in clinical trials who experienced recovery that would not be possible without the innovation of new treatments. Being able to use his math and programming background to be part of similar cancer research via the Department of Systems Biology has been a major driver of his interest in medicine. He is grateful to the Califano Lab for this opportunity. Now in medical school here at CUIMC, he hopes to bring insights from the clinic to computational research in the lab, and vice versa.

Education History

Columbia University VP&S, M.D. anticipated in 2027
Carleton College, B.A. in Mathematics in 2021
 

Publications

Malagola E, Vasciaveo A, Ochiai Y, Kim W, Zheng B, Zanella L, Wang ALE, Middelhoff M, Nienhüser H, Deng L, Wu F, Waterbury QT, Belin B, LaBella J, Zamechek LB, Wong MH, Li L, Guha C, Cheng CW, Yan KS, Califano A, Wang TC. Isthmus progenitor cells contribute to homeostatic cellular turnover and support regeneration following intestinal injury. Cell. 2024 Jun 6;187(12):3056-3071.e17. 

Hu LZ, Douglass E, Turunen M, Pampou S, Grunn A, Realubit R, Antolin AA, Wang ALE, Li H, Subramaniam P, Mundi PS, Karan C, Alvarez M, Califano A. Elucidating Compound Mechanism of Action and Polypharmacology with a Large-scale Perturbational Profile Compendium. bioRxiv [Preprint]. 2024 Jun 27:2023.10.08.561457.

Vlahos L, Obradovic A, Worley J, Tan X, Howe A, Laise P, Wang ALE et al. Systematic, protein activity-based characterization of Single Cell State [Internet]. Cold Spring Harbor Laboratory; 2023 [cited 2024 Aug 22]. Available from: https://www.biorxiv.org/content/10.1101/2021.05.20.445002v5.full 

Laise, P. Wang ALE et al. (2022) Developmental and MAPK-responsive transcription factors drive distinct malignant subtypes and genetic dependencies in pancreatic cancer, bioRxiv. Available at: https://www.biorxiv.org/content/10.1101/2020.10.27.357269v2