Postdoctoral Research Scientist
Antonio Gomes is a postdoctoral research scientist in the Wang Lab. He is interested in understanding biology using quantitative models, especially to address questions related to gene regulation, evolution, and drug resistance. His current research focuses on lateral gene transfer in microorganisms, particularly on gaining a mechanistic understanding of the effect of regulatory regions on horizontal gene transfer and its consequences in microbial evolution.
Antonio completed his PhD in bioinformatics at Boston University, where he studied the gene regulatory network of Mycobacterium tuberculosis.
PhD, Boston University
MSc, Universidade de Brasília
Molecular Biology (topic: Biophysics)
BSc, Universidade de Brasília
Johns NI, Blazejewski T, Gomes AL, Wang HH. Principles for designing synthetic microbial communities. Curr Opin Microbiol. 2016 Apr 13;31:146-153.
Gomes AL, Abeel T, Peterson M, Azizi E, Lyubetskaya A, Carvalho L, Galagan J. Decoding ChIP-Seq peaks with a double-binding signal refines binding peaks to single-nucleotide and predicts cooperative interaction. Genome Res. 2014 Jul 14.
Galagan JE, Minch K*, Peterson M*, Lyubetskaya A*, Azizi E*, Sweet L*, Gomes A*, et al. The Mycobacterium tuberculosis regulatory network and hypoxia. Nature. 2013 Jul 11;499(7457):178-83.
Gomes AL, Galagan JE, Segrè D. Resource competition may lead to effective treatment of antibiotic resistant infections. PLoS One. 2013 Dec 13;8(12):e80775.
Rereira de Araújo AF, Gomes AL, Bursztyn AA, Shakhnovich EI. Native atomic burials, supplemented by physically motivated hydrogen bond constraints, contain sufficient information to determine the tertiary structure of small globular proteins. Proteins. 2008 Feb 15;70(3):971-83.
Gomes AL, Rezende JR, Araujo AFP, Shaknovich EI. Description of atomic burials in compact globular proteins by Fermi-Dirac probability distributions. Proteins. 2007 Feb 1;66(2):304-20.
* Indicates authors contributed equally