Beatrice Salvatori

Beatrice Salvatori

Titles

Adjunct Associate Research Scientist

Beatrice Salvatori is a postdoctoral research scholar in the Califano Lab. She joined the group in 2013 as a molecular biologist, bringing expertise in the dissection and analysis of non-coding RNA regulatory pathways relevant to human cancer. Applying this approach in the context of the multilayer regulation of gene expression, she is focusing on competing endogenous RNA- (ceRNA) derived networks as well as miRNA activity in breast tumors.

Prior to joining Columbia University, Beatrice spent one year as an AIRC Postdoctoral Research Fellow working on long non-coding RNAs (lncRNAs) in hematological malignancies in the lab of Irene Bozzoni (Sapienza University of Rome). She also obtained her PhD degree there in 2012, studying the role of miRNAs in acute myeloid leukemias.


Education History

PhD, Sapienza University of Rome
Genetics and Molecular Biology

Master's Degree, Sapienza University of Rome
Genetics and Molecular Biology

Bachelor's Degree, Sapienza University of Rome
Biological Science


Publications

Hughes JM, Legnini I, Salvatori B, Masciarelli S, Marchioni M, Fazi F, Morlando M, Bozzoni I, Fatica A. C/EBPα-p30 protein induces expression of the oncogenic long non-coding RNA UCA1 in acute myeloid leukemia. Oncotarget. 2015 Jul 30;6(21):18534-44.

Hughes JM, Salvatori B, Giorgi FM, Bozzoni I, Fatica A. CEBPA-regulated lncRNAs, new players in the study of acute myeloid leukemia. J Hematol Oncol. 2014 Sep 25;7:69.

Iosue I, Quaranta R, Masciarelli S, Fontemaggi G, Batassa EM, Bertolami C, Ottone T, Divona M, Salvatori B, Padula F, Fatica A, Lo-Coco F, Nervi C, Fazi F. Argonaute 2 sustains the gene expression program driving human monocytic differentiation of acute myeloid leukemia cells. Cell Death Dis. 2013 Nov 21;4:e926.

Salvatori B, Iosue I, Mangiavacchi A, Loddo G, Padula F, Chiaretti S, Peragine N, Bozzoni I, Fazi F, Fatica A. The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells. Cell Death Dis. 2012 Oct 25;3:e413.

Salvatori B, Iosue I, Djodji Damas N, Mangiavacchi A, Chiaretti S, Messina M, Padula F, Guarini A, Bozzoni I, Fazi F, Fatica A. Critical role of c-Myc in acute myeloid leukemia involving direct regulation of miR-26a and histone methyltransferase EZH2. Genes Cancer. 2011 May;2(5):585-92.

De Marchis ML, Ballarino M, Salvatori B, Puzzolo MC, Bozzoni I, Fatica A. A new molecular network comprising PU.1, interferon regulatory factor proteins and miR-342 stimulates ATRA-mediated granulocytic differentiation of acute promyelocytic leukemia cells. Leukemia. 2009 May;23(5):856-62.


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