Chaitanya Rastogi

Chaitanya Rastogi


Graduate Student

I am currently a graduate student at Columbia University in Harmen Bussemaker’s laboratory. My research is focused on developing biophysics-based models for describing protein-DNA interactions using high-throughput sequencing data. In particular, I am interested in using technologies such as ChIP, DNase, and SELEX to better understand how epigenetic modifications such as methylation and chromatin structure affect transcription factor binding.

Prior to working in Professor Bussemaker’s lab, I worked in quantum optics research groups for three years. During my time there, I developed and fabricated optical resonators for a variety of applications ranging from atomic clocks to quantum computers.

I am also currently a 2014-2015 awardee of the Training Grant in Bioinformatics and Computational Biology.

Education History

MS, California Institute of Technology
Electrical Engineering

BS, California Institute of Technology
Applied Physics


Rao S, Carolina Dantas Machado A, Zhou T, Rastogi C, Bussemaker HJ, Rohs R. 22 evolving insights on how cytosine methylation affects protein-DNA binding. J Biomol Struct Dyn. 2015 May;33 Suppl 1:12.

Dantas Machado AC, Zhou T, Rao S, Goel P, Rastogi C, Lazarovici A, Bussemaker HJ, Rohs R. Evolving insights on how cytosine methylation affects protein-DNA binding. Brief Funct Genomics. 2014 Oct 14. 

Riley T, Slattery M, Abe N, Rastogi C, Mann R, Bussemaker H. SELEX-seq: a method for characterizing the complete repertoire of binding site preferences for transcription factor complexes. In Hox Genes. Methods in Molecular Biology, Vol. 1196. Y. Graba and R. Rezsohazy, Eds. New York: Springer. 2014. 

Hodges JS, Yao NY, Mclaurin D, Rastogi C, Lukin MD, Englund D. Timekeeping with electronic spin states in diamond. Phys Rev A. 2013 Mar;87(3):032118.

Bandyopadhyay D, Sharma A, Rastogi C. Dewetting of the thin liquid bilayers on topographically patterned substrates: formation of microchannel and microdot arrays. Langmuir. 2008 Dec 16;24(24)14048-58.


Lab Staff