Guojie Zhong is a PhD student in Dr. Yufeng Shen’s lab. His research interests involve different topics regarding to human genetics of developmental disorders, including: 1. Developing statistical learning methods that leverage large-scale exome sequencing and single cell sequencing data to understand human disease genetics. 2. Developing machine learning tools to predict variant functional effects using representations of protein sequence, structure, and functions. 3. Cross-disease genetics of several developmental disorders including autism, congenital heart disease, congenital diaphragmatic hernia, etc.

 

Prior to Columbia, Guojie completed his undergraduate studies at Peking University, where he worked in Dr. Zemin Zhang’s Lab, developing computational methods to infer cellular spatial organization and cellular interaction from single cell genomics data.