Fellow, Department of Systems Biology
Jeremy Worley is an associate research scientist in the Califano group. His broad interest is in understanding how cancer cells reprogram themselves to thrive in adverse conditions. To do so, he combines single-cell RNA sequencing, CRISPR based gene-perturbation, and computational methods for identifying the key regulators of cell-state. Ultimately, he wants to use this methodology not only to understand cancer but, more generally, the molecular biology of age-related disease.
PhD, University of Arizona
Molecular and Cellular Biology
JD, University of California, Davis School of Law
BA, University of California, Irvine
Ohkura M, Worley JJ, Hughes-Hallett JE, Fisher JS, Love BC, Arnold AE, Orbach MJ. Ophidiomyces ophiodiicola on a captive black racer (Coluber constrictor) and a garter snake (Thamnophis sirtalis) in Pennsylvania. J Zoo Wildl Med. 2016 Mar;47(1):341-6.
Worley J, Sullivan A, Luo X, Kaplan ME, Capaldi AP. Genome-wide analysis of the TORC1 and osmotic stress signaling network in Saccharomyces cerevisiae. G3 (Bethesda). 2015 Dec 17;6(2):463-74.
Worley J, Luo X, Capaldi AP. Inositol pyrophosphates regulate cell growth and the environmental stress response by activating the HDAC Rpd3L. Cell Rep. 2013 May 30;3(5):1476-82.