Jiayao Wang

Overview

Titles

Postdoctoral Research Scientist

Email
jw3514@cumc.columbia.edu

Lab

Dennis Vitkup

Jiayao is a Postdoctoral Research Scientist in the Vitkup Lab. His research integrates genetics data with single-cell transcriptomic, and brain connectivity data to understand how genetic mutations converge on specific brain circuits and cell types that underlying psychiatric disorders. 

Education History

Ph.D., Biomedical Informatics, Columbia University

B.S., Information Engineering, Shanghai Jiao Tong University

Publications

Herrlinger SA, Wang J, Rao BY, Chang J, Gogos JA, Losonczy A, Vitkup D. Rare mutations implicate CGE interneurons as a vulnerable axis of cognitive deficits across psychiatric disorders. bioRxiv [Preprint]. 2025 Mar 31:2025.03.28.645799. 

Tabansky I, Tanaka AJ, Wang J, Zhang G, Dujmovic I, Mader S, Jeganathan V, DeAngelis T, Funaro M, Harel A, Messina M, Shabbir M, Nursey V, DeGouvia W, Laurent M, Blitz K, Jindra P, Gudesblatt M; Regeneron Genetics Center; King A, Drulovic J, Yunis E, Brusic V, Shen Y, Keskin DB, Najjar S, Stern JNH. Rare variants and HLA haplotypes associated in patients with neuromyelitis optica spectrum disorders. Front Immunol. 2022 Oct 4;13:900605.

Chiang AH, Chang J, Wang J, Vitkup D. Exons as units of phenotypic impact for truncating mutations in autism. Mol Psychiatry. 2021 May;26(5):1685-1695.

Wang J, Ahimaz PR, Hashemifar S, Khlevner J, Picoraro JA, Middlesworth W, Elfiky MM, Que J, Shen Y, Chung WK. Novel candidate genes in esophageal atresia/tracheoesophageal fistula identified by exome sequencing. Eur J Hum Genet. 2021 Jan;29(1):122-130.

Zhu N, Welch CL, Wang J, Allen PM, Gonzaga-Jauregui C, Ma L, King AK, Krishnan U, Rosenzweig EB, Ivy DD, Austin ED, Hamid R, Pauciulo MW, Lutz KA, Nichols WC, Reid JG, Overton JD, Baras A, Dewey FE, Shen Y, Chung WK. Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease. Genome Med. 2018 Jul 20;10(1):56.