Jinzhou Yuan


Postdoctoral Research Scientist

I am a postdoctoral research scientist in Peter Sims’ laboratory. My current research interests include both the development and application of microwell-based single cell mRNA sequencing technology.

Prior to my recruitment at Dr. Sims’ group, I obtained my PhD in mechanical engineering from the University of Pennsylvania. There I studied locomotion of the small model organism C. elegans with a focus on the fluid mechanical aspect of swimming. My work included developing microwell/microfluidics-based high throughput technologies for monitoring behavior of individual C. elegans as well as sorting C. elegans based on their motility.

Related news: Automated, Single Cell RNA-Seq Enables Research on Tumor Ecology

Education History

PhD, University of Pennsylvania
Mechanical Engineering


Yuan J, Sims PA. An automated microwell platform for large-scale single cell RNA-Seq. Sci Rep. 2016 Sep 27;6:33883.

Yuan J, Raizen DM, Bau HH. A hydrodynamic mechanism for attraction of undulatory microswimmers to surfaces. J R Soc Interface. 2015 Aug 6;12(109):20150227. 

Yuan J, Zhou J, Raizen DM, Bau HH. High-throughput, motility-based sorter for microswimmers such as C. elegans. Lab Chip. 2015 Jul 7;15(13):2790-8.

Yuan J, Raizen DM, Bau HH. Propensity of undulatory swimmers, such as worms, to go against the flow. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3606-11.

Yuan J, Raizen DM, Bau HH. Gait synchronization in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2014 May 13;111(19):6865-70.

Yuan J, Pillarisetti A, Goldman YE, Bau HH. Orienting actin filaments for directional motility of processive myosin motors. Nano Lett. 2013 Jan 9;13(1):79-84.

Belfer SJ, Chuang HS, Freedman BL, Yuan J, Norton M, Bau HH, Raizen DM. Caenorhabditis-in-drop array for monitoring C. elegans quiescent behavior. Sleep. 2013 May 1;36(5):689-698G.

Liu J, Qu W, Yuan J, Wang S, Qiu J, Zheng C. Theoretical studies of properties and reactions involving mercury species present in combustion flue gases. Energy Fuels. 2010 Jul 16;24(1):117-122.