Postdoctoral Research Scientist
My research interests include the design principles of biological systems and their regulatory logic. During my graduate studies my work focused on the effect of topology on the evolution of complex networks and statistical systems for stochastic growth. As a postdoctoral research scientist in the Tavazoie lab I developed a novel experimental method to uncover underlying patterns of regulation in 3’UTR sequences of mammalian organisms and analyze their effect in mRNA stability and translation. In parallel I am developing computational methods to predict gene expression dynamics from sequence elements and to unveil the combinatorial regulatory logic underlying such dynamics.
PhD, University of Chicago
MS, University of Chicago
MS, National Technical University of Athens, Greece
Electrical and Computer Engineering
Oikonomou P, Goodarzi H, Tavazoie S. Systematic identification of regulatory elements in conserved 3’ UTRs of human transcripts. Cell Rep. 2014 Apr 10;7(1):281-92.
Goodarzi H, Najafabadi HS, Oikonomou P, Greco TM, Fish L, Salavati R, Cristea IM, Tavazoie S. Systematic discovery of structural elements governing stability of mammalian messenger RNAs. Nature. 2012 Apr 8;485(7397):264-8.
Park H, Oikonomou P, Guet CC, Cluzel P. Noise underlies switching behavior of the bacterial flagellum. Biophys J. 2011 Nov 16;101(10):2336-40.
Oikonomou P, Rushkin I, Gruzberg IA, Kadanoff LP. Global properties of Stochastic Loewner evolution driven by Lévy processes. J Stat Mech. 2008;P01019
Oikonomou P, Cluzel P. Effects of topology on network evolution. Nat Phys. 2006;2:532-36.
Rushkin I, Oikonomou P, Kadanoff LP, Gruzberg IA. Stochastic Loewner evolution driven by Lévy processes. J Stat Mech. 2006;P01001
Lee M, Oikonomou P, Segalova P, Rosenbaum TF, Hoekstra AF Th, Littlewood PB. The electron glass in a switchable mirror: relaxation, aging and universality. J Phys Condens. Matter. 2005;17: L439-L444.