Sergey Pampou

Sergey Pampou


Associate Research Scientist
Head, Functional Genomics, High-Throughput Screening, Columbia Genome Center

Sergey Pampou is an associate research scientist in the High-Throughput Screening Facility at Columbia Genome Center. His primary focus of research is cell-based assay development and implementation with the focus on high-content assays for human diseases. Previously he was working on bacterial functional genomics studies, constructing microarrays for pathogen human bacteria (L. pneumophila). His PhD thesis work at Moscow Cardiology Research Center was dedicated to studying the viral involvement in pathogenesis of atherosclerosis.

Education History

MD, Russian State Medical University, Moscow, Russia
Medical Biochemistry

PhD, Cardiology Research Center, Moscow, Russia
Cell Biology


Hovel-Miner G, Pampou S, Faucher SP, Clarke M, Morozova I, Morozov P, Russo JJ, Shuman HA,Kalachikov S. SigmaS controls multiple pathways associated with intracellular multiplication of Legionella pneumophila. J Bacteriol. 2009 Apr;191(8):2461-73.

Xie Y, Deng S, Thomas CJ, Liu Y, Zhang YQ, Rinderspacher A, Huang W, Gong G, Wyler M, Cayanis E, Aulner N, Többen U, Chung C, Pampou S, Southall N, Vidović D, Schürer S, Branden L, Davis RE, Staudt LM, Inglese J, Austin CP, Landry DW, Smith DH, Auld DS. Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFkappaB activity within two separate high-throughput screens of NFkappaB activation. Bioorg Med Chem Lett. 2008 Jan 1;18(1):329-35.

Suwwan de Felipe K, Pampou S, Jovanovic OS, Pericone CD, Ye SF, Kalachikov S, Shuman HA. Evidence for acquisition of Legionella type IV secretion substrates via interdomain horizontal gene transfer. J Bacteriol. 2005 Nov;187(22):7716-26.

Morozova I, Pampou S, Suwwan de Felipe K, Chien M, Shi S, Sheng H, Chen J, Ju J, Kalachikov S, Shuman HA, Russo JJ. Host interaction and horizontal gene transfer in Legionella pneumophila. Jpn J Bacteriol. 2005;60:60.

Chien M, Morozova I, Shi S, Sheng H, Chen J, Gomez SM, Asamani G, Hill K, Nuara J, Feder M, Rineer J, Greenberg JJ, Steshenko V, Park SH, Zhao B, Teplitskaya E, Edwards JR, Pampou S, Georghiou A, Chou IC, Iannuccilli W, Ulz ME, Kim DH, Goldsberry C, Morozov P, Fischer SG, Segal G, Qu X, Rzhetsky A, Zhang P, Cayanis E, De Jong PJ, Ju J, Kalachikov S, Shuman HA, Russo JJ. The genomic sequence of the accidental pathogen Legionella pneumophila. Science. 2004 Sep 24;305(5692):1966-8.

Wang Y, Pampou S, Fujikawa K, Varticovski L. Opposing effect of angiopoietin-1 on VEGF-mediated disruption of endothelial cell-cell interactions requires activation of PKC beta. J Cell Physiol. 2004 Jan;198(1):53-61.

Smirnov VN, Pampou S, Ryaskina SS, Bystrevskaya VB. Cytomegalovirus infection and atherosclerosis. Atherosclerosis. 2001;2(Suppl.):37.

Wang YH, Pampou S, Varticovski L. The mechanism by which angiopoietin 1 inhibits VEGF-mediated vascular permeability. “Blood”, 2000, v. 96, p. 3940.

Pampou S, Gnedoy SN, Bystrevskaya VB, Smirnov VN, Chazov EI, Melnick JL, DeBakey ME. Cytomegalovirus genome and the immediate-early antigen in cells of different layers of human aorta. Virchows Arch. 2000 Jun;436(6):539-52.

Pampou S, Bystrevskaya VB, Smirnov VN, Melnick JL, DeBakey ME Chazov EI. The immediate-early antigen of cytomegalovirus in cells of different layers of human aorta. Kardiologiya. 2000;7:27-35.

Pampou S, Gnedoy SN, Bystrevskaya VB, Smirnov VN, Melnick JL, DeBakey ME Chazov EI. Cytomegalovirus in human aortic endothelium, Angiology and Vascular Surgery. 1999;5:137-50.

Smirnov VN, Bystrevskaya VB, Pampou S, Chazov EI, Melnick JL, DeBakey ME. Cytomegalovirus infection of human aortic endothelium. Atherosclerosis. 1997;134:283.