Zicheng Wang

Overview

Titles

Postdoctoral Research Scientist

Email
zw2595@cumc.columbia.edu

Website

Shen Lab of Computational Genomics

Lab

Yufeng Shen

As a postdoctoral research scientist at Columbia University, Zicheng applies his bioinformatics expertise and large language models (LLM) skills to study computational immunology and single-cell sequencing. He has co-authored multiple publications in high-impact journals and developed novel algorithms and tools for analyzing and visualizing complex biological data.

Education History

Tsinghua University Doctor of Philosophy - PhD, Biomathematics Sep 2012 - Jan 2019

Publications

Fu, J., Wang, Z., Martinez, M., Obradovic, A., Jiao, W., Frangaj, K., Jones, R., Guo, X.V., Zhang, Y., Kuo, W.I. and Ko, H.M., 2023. Plasticity of intragraft alloreactive T cell clones in human gut correlates with transplant outcomes. Journal of Experimental Medicine, 221(1), p.e20230930.

Wang, Z. and Shen, Y., 2023. SABRE: Self-Attention Based model for predicting T-cell Receptor Epitope Specificity. bioRxiv, pp.2023-10.

Connors, T.J., Matsumoto, R., Verma, S., Szabo, P.A., Guyer, R., Gray, J., Wang, Z., Thapa, P., Dogra, P., Poon, M.M. and Rybkina, K., 2023. Site-specific development and progressive maturation of human tissue-resident memory T cells over infancy and childhood. Immunity, 56(8), pp.1894-1909.

Poon, M.M., Caron, D.P., Wang, Z., Wells, S.B., Chen, D., Meng, W., Szabo, P.A., Lam, N., Kubota, M., Matsumoto, R. and Rahman, A., 2023. Tissue adaptation and clonal segregation of human memory T cells in barrier sites. Nature Immunology, 24(2), pp.309-319.

Fu, J., Zuber, J., Shonts, B., Obradovic, A., Wang, Z., Frangaj, K., Meng, W., Rosenfeld, A.M., Waffarn, E.E., Liou, P. and Lau, S.P., 2021. Lymphohematopoietic graft-versus-host responses promote mixed chimerism in patients receiving intestinal transplantation. The Journal of Clinical Investigation, 131(8).

Wang Z, Lou H, Wang Y, et al. GePMI: A statistical model for personal intestinal microbiome identification. Npj Biofilms & Microbiomes. 2018, 4(1): 20.