Affiliate Member, Program for Mathematical Genomics
Assistant Professor of Biochemistry and Molecular Biophysics
Anum Glasgow is an assistant professor in the Department of Biochemistry and Molecular Biophysics at Columbia University. She received a PhD from UC Berkeley, where she engineered a bacterial protein secretion system for applications in biotech in Dr. Danielle Tullman-Ercek’s group. Anum pivoted from her experimental background to work in computational biophysics to build biological sensors and antiviral therapeutics as a postdoctoral fellow in Dr. Tanja Kortemme’s group at UC San Francisco. Her postdoctoral work includes the first example of a de novo-designed chemically inducible dimerization system, in which two proteins bind a small molecule to generate programmable cellular responses. During the COVID-19 pandemic, Anum co-led a team to rapidly develop a receptor trap therapeutic for treating SARS-CoV-2 infections. Anum continues to build and apply experimental and computational approaches to probe how protein systems evolve, undergo conformational changes, and interact with other biomolecules, while maintaining a focus on biotherapeutics development.