Aris Floratos

Selected Publications

Smith KC, Chawla DG, Dhillon BK, Ji Z, Vita R, van der Leest EC, Weng JYJ, Tang E, Abid A; Human Immunology Project Consortium (HIPC); Peters B, Hancock REW, Floratos A, Kleinstein SH. A curated collection of human vaccination response signatures. Sci Data. 2022 Nov 8;9(1):678.

Myer PA, Kim H, Blümel AM, Finnegan E, Kel A, Thompson TV, Greally JM, Prehn JH, O'Connor DP, Friedman RA, Floratos A, Das S. Master Transcription Regulators and Transcription Factors Regulate Immune-Associated Differences Between Patients of African and European Ancestry With Colorectal Cancer. Gastro Hep Adv. 2022;1(3):328-341.

Nicoletti P, Carr DF, Barrett S, McEvoy L, Friedmann PS, Shear NH, Nelson MR, Chiriac AM, Blanca-López N, Cornejo-García JA, Gaeta F, Nakonechna A, Torres MJ, Caruso C, Valluzzi RL, Floratos A, Shen Y, Pavlos RK, Phillips EJ, Demoly P, Romano A, Blanca M, Pirmohamed M. Beta-lactam-induced immediate hypersensitivity reactions: A genome-wide association study of a deeply phenotyped cohort. J Allergy Clin Immunol. 2021 May;147(5):1830-1837.e15.

Aksoy BA, Dancík V, Smith K, Mazerik JN, Ji Z, Gross B, Nikolova O, Jaber N, Califano A, Schreiber SL, Gerhard DS, Hermida LC, Jagu S, Sander C, Floratos A, Clemons PA. CTD2 Dashboard: a searchable web interface to connect validated results from the Cancer Target Discovery and Development Network. Database (Oxford). 2017 Jan 1;2017.

Nelson MR, Tipney H, Painter JL, Shen J, Nicoletti P, Shen Y, Floratos A, Sham PC, Li MJ, Wang J, Cardon LR, Whittaker JC, Sanseau P. The support of human genetic evidence for approved drug indications. Nat Genet. 2015 Aug;47(8):856-60. 

NicolettiP, BansalM, LefebvreC, GuarnieriP, ShenY, Pe'erI, CalifanoA, Floratos A. ABC transporters and the proteasome complex are implicated in susceptibility to Stevens-Johnson syndrome and toxic epidermal necrolysis across multiple drugs. PLoS One. 2015 Jun 25;10(6):e0131038. 

Contreras JL, Floratos A, Holden AL. The International Serious Adverse Events Consortium's data sharing model. Nat Biotechnol. 2013 Jan;31(1):17-9.

Nicoletti P, Cartsos VM, Aggarwal P, Palaska PK, Shen Y, Floratos A, Zavras AI. Genome-wide pharmacogenetics of bisphosphonate-induced osteonecrosis of the jaw: the role of RBMS3 . Oncologist. 2012;17(2):279-87.

Shen Y, Nicoletti P, Floratos A, Pirmohamed M, Molokhia M, Geppetti P, Benemei S, Giomi B, Schena D, Vultaggio A, Stern R, Daly MJ, John S, Nelson MR, Pe’er I. Genome-wide association study of serious blistering skin rash caused by drugs . Pharmacogenomics J. 2011 Jan 11.

Floratos A, Smith K, Ji Z, Watkinson J, Califano A. geWorkbench: an open source platform for integrative genomics . Bioinformatics. 2010 Jul 15;26(14):1779-1780.

Daly AK, Donaldson PT, Bhatnagar P, Shen Y, Pe'er I, Floratos A, Daly MJ, Goldstein DB, John S, Nelson MR, Graham J, Park BK, Dillon JF, Bernal W, Cordell HJ, Pirmohamed M, Aithal GP, Day CP. HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin . Nat Genet. 2009 Jul;41(7):816-9.

Rigoutsos I, Huynh T, Floratos A, Parida L. Dictionary-driven protein annotation . Nucleic Acids Res., 2002; 30(17):3901-3916.