Guy Sella

Selected Publications

Hayward, L. and G. Sella. Polygenic adaptation after a sudden change in environment. BioRxiv. 2019.

Amster, G., Murphy, D., Milligan, W. and G. Sella. Changes in life history and population size can explain relative neutral diversity levels on X and autosomes in extant human populations. BioRxiv. 2019. 

Amster, G. and G. Sella. Life history effects on neutral diversity levels of autosomes and sex chromosomes. BioRxiv. 2019.

Sella G. and N. Barton. Thinking about the evolution of complex traits in the era of GWAS. 2019. Annual Reviews in Genomics and Human Genetics 20: 461-493.

Fuller Z., Berg J., Mostafavi H., Sella G. and M. Przeworski. Measuring intolerance to mutation in human genetics. 2019. Nature Genetics 51: 772–776.

Simons Y., Bullaughey K., Hudson R. and G. Sella. A population genetic interpretation of GWAS findings for human quantitative traits. 2018. PLoS Biol 16: e2002985.

Simons Y. and G. Sella. The impact of recent population history on the deleterious mutation load in humans and close evolutionary relatives. 2016. Curr Opin Genetics Dev 41: 150-158.

Elyashiv E, Sattath S, Hu TT, Strutsovsky A, McVicker G, Andolfatto P, Coop G, Sella G. A genomic map of the effects of linked selection in Drosophila. PLoS Genet. 2016 Aug 18;12(8):e1006130.

Amster G, Sella GLife history effects on the molecular clock of autosomes and sex chromosomes. Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1588-93. 

Simons YB, Turchin MC, Pritchard JK*, Sella G*. The deleterious mutation load is insensitive to recent population history. Nat Genet. 2014 Mar;46(3):220-4.

Hernandez RD, Kelley JL, Elyashiv E, Melton SC, Auton A, McVean G; 1000 Genomes Project., Sella G*, Przeworski M*. Classic selective sweeps were rare in recent human evolution. Science. 2011 Feb 18;331(6019):920-4.

Sattath S, Elyashiv E, Kolodny O, Rinott Y, Sella GPervasive adaptive protein evolution apparent in diversity patterns around amino acid substitutions in Drosophila simulans. PLoS Genet. 2011 Feb 10;7(2):e1001302. 

Sella G, Petrov DA, Przeworski M, Andolfatto P. Pervasive natural selection in the Drosophila genome? PLoS Genet. 2009 Jun;5(6):e1000495.

Macpherson JM+, Sella G+, Davis JC, Petrov DA. Genomewide spatial correspondence between nonsynonymous divergence and neutral polymorphism reveals extensive adaptation in Drosophila. Genetics. 2007 Dec;177(4):2083-99.

Sella G, Ardell DH. The coevolution of genes and genetic codes: Crick's frozen accident revisited. J Mol Evol. 2006 Sep;63(3):297-313. 

Sella G, Hirsh AE. The application of statistical physics to evolutionary biology. Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9541-6.

* joint senior authors
+ joint first authors 

For a full list of publications, visit Google Scholar.