Sara Zaccara

Selected Publications

Zaccara S, Jaffrey SR.A Unified Model for the Function of YTHDF Proteins in Regulating m6A Modified mRNA. Cell. 2020 Jun 25;181(7):1582-1595.e18.

Zaccara S, Ries RJ, Jaffrey SR. Reading, writing and erasing mRNA methylation. Nat Rev Mol Cell Biol. 2019 Oct;20(10):608-624.

Ries RJ, Zaccara S, Klein P, Olarerin-George A, Namkoong S, Pickering BF, Patil DP, Kwak H, Lee JH, Jaffrey SR. m6A enhances the phase separation potential of mRNA. Nature. 2019 Jul;571(7765):424-428. doi: 10.1038/s41586-019-1374-1.

Wu J, Zaccara S, Khuperkar D, Kim H, Tanenbaum ME, Jaffrey SR. Live imaging of mRNA using RNA-stabilized fluorogenic proteins. Nat Methods. 2019 Sep;16(9):862-865. doi: 10.1038/s41592-019-0531-7. Epub 2019 Aug 30. 

Rizzotto D*, Zaccara S*, Rossi A, Galbraith MD, Andrysik Z, Pandey A, Sullivan KD, Quattrone A, Espinosa JM, Dassi E, Inga A. Nutlin-Induced Apoptosis Is Specified by a Translation Program Regulated by PCBP2 and DHX30.  Cell Rep .  2020 Mar 31;30(13):4355-4369.e6. doi: 10.1016/j.celrep.2020.03.011