Pandemics Past & Present: Investigating Microbial Origins, Evolution, and Biodiversity through Metatranscriptomics and Ancient DNA
Metatranscriptomic analysis of invertebrates is transforming our understanding of viral evolution, revealing the ancestry of many vertebrate viruses, challenging traditional classification systems, and highlighting that most RNA viruses are unlikely to be associated with disease in their hosts. Additionally, Analyses of ‘ancient DNA’ from archival human remains can inform on past epidemics including two infamous bacterial diseases – plague and cholera – where recovery of ancient genomes is now possible.
Eddie Holmes is an NHMRC Australia Fellow and Professor at the University of Sydney, Australia. Previously, Eddie was the Verne M. Willaman Chair in the Life Sciences at The Pennsylvania State University. Eddie received his undergraduate degree from the University of London, his PhD from the University of Cambridge and subsequently held various positions at the University of Oxford, including University Lecturer in Evolutionary Biology and Fellow of New College. He was elected Fellow of the Australian Academy of Science in 2015.
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