Barry Honig

Selected Publications

Koss, H., Honig, B., Shapiro, L. and Palmer III, A.G. (2021) Cadherin-11 Dimerization Multi-site Kinetics: Combined Partial Unfolding and Strand-swapping. Structure

Lasso, G., Honig, B. and Shapira, S. (2021) A Sweep of Earth’s Virome Reveals Host-Guided Viral Protein Structural Mimicry and Points to Determinants of Human Disease. Cell Systems. 12:82-91. Featured article.

Broyde, J., Simpson, D.R., Murray, D., Paull, E.O., Chu, B. W., Tagore, S., Jones, S.J., Griffin, A.T., Giorgi, F.M., Lachmann, A., Jackson, P., Sweet-Cordero, E.A., Honig, B. and Calfiano, A. (2021) Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses. Nature Biotech. 39:215-224.

Honig, B. and Shapiro, L. (2020) Adhesion Protein Structure, Molecular Affinities, and Principles of Cell-Cell Recognition. Cell 181:520-535.

Sergeeva, A.P., Katsamba, P.S., Cosmanescu, F., Brewer, J.J., Ahlsen, G., Mannepalli, S., Shapiro, L. and Honig B. (2020) DIP/Dpr Interactions and the Evolutionary Design of Specificity in Protein Families. Nature Comm. 11:2125.

Lasso, G., Mayer, S.V., Winkelmann, E.R., Chu, T., Elliot, O., Patino-Galindo, J.A., Park, K., Rabadan, R., Honig, B. and Shapira, S. (2019) A Structure Informed Atlas of Human-Virus Interactions. Cell 178:1526-1541.

Brasch, J., Goodman, K.M., Noble, A.J., Rapp, M., Mannepalli, S., Bahna, F., Dandey, V.P., Bepler, T., Berger, B., Maniatis, T., Potter, C.S., Carragher, B., Honig, B. and Shapiro, L. (2019) Visualization of Clustered Protocadherin Neuronal Self-Recognition Complexes. Nature 569:280-283.

Hwang, H., Dey, F., Petrey, D. and Honig, B. (2017) Structure-based Prediction of Ligand-protein Interactions on a Genome-wide Scale. Proc. Natl. Acad. of Sci. 114:13685-13690.

Garzon, J.I., Deng, L., Murray, D., Shapira, S., Petrey, D. and Honig, B. (2016) A Computational Interactome and Functional Annotation for the Human Proteome. eLife 5:e18715.

Rubinstein, R., Thu, C.A., Goodman,K.M., Wolcott, H.N., Bahna, F., Mannepalli, S., Ahlsen, G., Chevee, M., Halim, A., Clausen, H., Maniatis, T., Shapiro, L. and Honig, B. (2015) Molecular Logic of Neuronal Self-recognition Through Protocadherin Domain Interactions. Cell 163:629-642.

Zhang, Q.C., Petrey, D., Deng, L., Qiang, L., Shi, Y., Thu, C.A., Bisikirska, B., Lefebvre, C., Accili, D., Hunter, T., Maniatis, T., Califano, A. and Honig, B. (2012) Structure-based Prediction of Protein-protein Interactions on a Genome-wide Scale. Nature 490:556 - 560.

Slattery, M., Riley, T., Liu, P., Abe, N., Gomez-Alcala, P., Dror, I., Zhou, T., Rohs, R., Honig, B., Bussemaker, H.J. and Mann, R.S. (2011) Cofactor Binding Evokes Latent Differences in DNA Binding Specificity Between Hox Proteins. Cell 147:1270-1282.

Zhang, Q.C., Petrey, D., Norel, R. and Honig, B. (2010) Protein Interface Conservation Across Structure Space. Proc. Natl. Acad. of Sci. 107:10896-10901.

Rohs, R., West, S.M., Sosinsky, A., Liu, P., Mann, R.S. and Honig, B. (2009) The Role of DNA Shape in Protein-DNA Recognition. Nature 461:1248-1253.