Chaolin Zhang

Selected Publications

Wu D, Schieren I, Qian Y, Zhang C, Jessell TM, de Nooij JC. A Role for Sensory end Organ-Derived Signals in Regulating Muscle Spindle Proprioceptor Phenotype. J Neurosci. 2019 May 29;39(22):4252-4267. doi: 10.1523/JNEUROSCI.2671-18.2019.

Lee H, Bao S, Qian Y, Geula S, Leslie J, Zhang C, Hanna JH, Ding L. Stage-specific requirement for Mettl3-dependent m6A mRNA methylation during haematopoietic stem cell differentiation. Nat Cell Biol. 2019 Jun;21(6):700-709. doi: 10.1038/s41556-019-0318-1. 

Feng H, Bao S, Rahman MA, Weyn-Vanhentenryck SM, Khan A, Wong J, Shah A, Flynn ED, Krainer AR, Zhang C. Modeling RNA-Binding Protein Specificity In Vivo by Precisely Registering Protein-RNA Crosslink Sites. Mol Cell. 2019 Jun 20;74(6):1189-1204.e6. doi: 10.1016/j.molcel.2019.02.002.

Bao X, Guo X, Yin M, Tariq M, Lai Y, Kanwal S, Zhou J, Li N, Lv Y, Pulido-Quetglas C, Wang X, Ji L, Khan MJ, Zhu X, Luo Z, Shao C, Lim DH, Liu X, Li N, Wang W, He M, Liu YL, Ward C, Wang T, Zhang G, Wang D, Yang J, Chen Y, Zhang C, Jauch R, Yang YG, Wang Y, Qin B, Anko ML, Hutchins AP, Sun H, Wang H, Fu XD, Zhang B, Esteban MA. Capturing the interactome of newly transcribed RNA. Nat Methods. 2018 Mar;15(3):213-220.

Jacko M, Weyn-Vanhentenryck SM, Smerdon JW, Yan R, Feng H, Williams DJ, Pai J, Xu K, Wichterle H, Zhang C. Rbfox Splicing Factors Promote Neuronal Maturation and Axon Initial Segment Assembly. Neuron. 2018 Feb 21;97(4):853-868.e6. 

Ustianenko D, Weyn-Vanhentenryck SM, Zhang C. Microexons: discovery, regulation, and function. Wiley Interdiscip Rev RNA. 2017 Jul;8.

Zhang C, Lee K-Y, Swanson MS, Darnell RB. Predicting clustered RNA-binding protein motif sites in the mammalian genome Nucleic Acids Res. In press 2013.

Wu J, Anczukow O, Krainer AR, Zhang MQ, Zhang C. OLego: Fast and sensitive mapping of spliced mRNA-Seq reads using small seeds . Nucleic Acids Res. In press 2013.

Zhang C, Darnell RB. Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data . Nat Biotechnol. 2011 Jun 1;29(7):607-14.

Zhang C, Frias MA, Mele A, Ruggiu M, Eom T, Marney CB, Wang H, Licatalosi DD, Fak JJ, Darnell RB. Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls . Science. 2010 Jul 23;329(5990):439-43.

Castle JC, Zhang C, Shah JK, Kulkarni AV, Kalsotra A, Cooper TA, Johnson JM. Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines . Nat Genet. 2008 Dec;40(12):1416-25.

Zhang C, Zhang Z, Castle J, Sun S, Johnson J, Krainer AR, Zhang MQ. Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2 . Genes Dev. 2008 Sep 15;22(18):2550-63.

Zhang C, Li W-H, Krainer AR, Zhang MQ. RNA landscape of evolution for optimal exon and intron discrimination . Proc Natl Acad Sci U S A . 2008 Apr 15;105(15):5797-802.

Zhang C, Hasting ML, Krainer AR, Zhang MQ. 2007. Dual-specificity splice sites function alternatively as 5' and 3' splice sites . Proc. Nat. Acad. Sci. USA 104: 15028-15033.