Diversity and Severity of Autism Symptoms Linked to Mutation Locations
In a recent study, led by Dennis Vitkup, PhD, researchers at Columbia University Vagelos College of Physicians and Surgeons have made an important step towards understanding the biological mechanisms underlying the cognitive and behavioral diversity of autism cases triggered by de novo truncating mutations.
Dynamics of Gut Bacteria Follow Ecological Laws
The seemingly chaotic bacterial soup of the gut microbiome is more organized than it first appears and follows some of the same ecological laws that apply to birds, fish, tropical rainforests, and even complex economic and financial markets, according to a new paper in Nature Microbiology by systems biologists at Columbia University Irving Medical Center.
Grad Spotlight: Brian Ji, PhD
For Brian Ji, the big draw to systems biology stemmed from his passion for applying quantitative approaches to understanding biology. Ji studied under Dr. Dennis Vitkup in the Vitkup lab and completed his thesis defense for systems biology in the fall of 2018. Also an MD student in Columbia’s Vagelos College of Physicians and Surgeons, Ji was attracted to Columbia because of the close interplay between the Systems Biology Department and the Columbia University Irving Medical Center. “Ultimately,” he says, “the opportunity to sit at the intersection between math, biology and medicine was too good to pass up.”
PhD Candidate Brian Ji Wins for Outstanding Research at Integrated Conference
Brian Ji, an MD/PhD student in systems biology and a member of the Vitkup Lab, delivered the winning talk at the Biennial Integrated Program Retreat. Ji, who discussed a novel experimental and computational method to understand spatiotemporal dynamics of the human gut microbiome, was one of six systems biology students who delivered research presentations at the conference.
Columbia Awarded NCI Center for Cancer Systems Biology
The Center for Cancer Systems Therapeutics (CaST) is developing a framework that can account for the dynamic nature of cancer and use this knowledge to disrupt the programs that maintain tumor survival.