Harris Wang

Selected Publications

Konaté MM, Plata G, Park J, Usmanova DR, Wang H, Vitkup D. Molecular function limits divergent protein evolution on planetary timescales. Elife. 2019 Sep 18;8. pii: e39705. doi: 10.7554/eLife.39705.

Ji BW, Sheth RU, Dixit PD, Huang Y, Kaufman A, Wang HH, Vitkup D. Quantifying spatiotemporal variability and noise in absolute microbiota abundances using replicate sampling. Nat Methods. 2019 Jul 15. doi: 10.1038/s41592-019-0467-y. 

Johns N, Gomes A, Yim SS, Yang A, Blazejewski T, Smillie C, Smith M, Alm E, Kosuri S, Wang H. Metagenomic mining of regulatory elements enables programmable species-selective gene expression. Nat Methods. 19 March 2018. 

Shen RU, Yim SS, Wu FL, Wang HH. Multiplex recording of cellular events over time on CRISPR biological tape. Science. 2017 Dec 15.

Bonde MT, Kosuri S, Genee HJ, Sarup-Lytzen K, Church GM, Sommer MO, Wang HH. Direct mutagenesis of thousands of genomic targets using microarray-derived oligonucleotides . ACS Synth Biol. 2014 Jun 20.

Bonde MT, Klausen MS, Anderson MV, Wallin AI, Wang HH, Sommer MO. MODEST: a web-based design tool for oligonucleotide-mediated genome engineering and recombineering . Nucleic Acids Res. 2014 Jul;42(Web Server issue):W408-15. 

Esvelt KM, Wang HH. Genome-scale engineering for systems and synthetic biology . Mol Syst Biol. 2013 Jan 22;9:641.

Wang HH, Huang PY, Xu G, Haas W, Marblestone A, Li J, Gygi S, Forster AC, Jewett MC, Church GM. Multiplexed in vivo His-tagging of enzyme pathways for in vitro single-pot multi-enzyme catalysis . ACS Synth Biol. 2012 Feb 16;1(2):43-52.

Wang HH, Kim H, Cong L, Jeong J, Bang D, Church GM. Genome-scale promoter engineering by coselection MAGE . Nat Methods. 2012 Jun;9(6):591-3.

Wang HH, Isaacs FJ, Carr PA, Sun ZZ, Xu G, Forest CR, Church GM. Programming cells by multiplex genome engineering and accelerated evolution . Nature. 2009 Aug 13;460(7257):894-8.