Kam Leong

Selected Publications

Mintz RL, Lao YH, Chi CW, He S, Li M, Quek CH, Shao D, Chen B, Han J, Wang S, Leong KW. CRISPR/Cas9-mediated mutagenesis to validate the synergy between PARP1 inhibition and chemotherapy in BRCA1-mutated breast cancer cells. Bioeng Transl Med. 2020 Jan 2;5(1):e10152. doi: 10.1002/btm2.10152.

He Z, Nie T, Hu Y, Zhou Y, Zhu J, Liu Z, Liu L, Leong KW, Chen Y, Mao HQ. A polyphenol-metal nanoparticle platform for tunable release of liraglutide to improve blood glycemic control and reduce cardiovascular complications in a mouse model of type II diabetes. J Control Release. 2019 Dec 12;318:86-97. doi: 10.1016/j.jconrel.2019.12.014. 

Chen R, Li L, Feng L, Luo Y, Xu M, Leong KW, Yao R. Biomaterial-assisted scalable cell production for cell therapy. Biomaterials. 2020 Feb;230:119627. doi: 10.1016/j.biomaterials.2019.11962.

Kim HS, Son YJ, Mao W, Leong KW, Yoo HS. Atom Transfer Radical Polymerization of Multishelled Cationic Corona for the Systemic Delivery of siRNA. Nano Lett. 2018 Jan 10;18(1):314-325. Epub 2017 Dec 18.

Charoensook SN, Williams DJ, Chakraborty S, Leong KW, Vunjak-Novakovic G. Bioreactor model of neuromuscular junction with electrical stimulation for pharmacological potency testing. Integr Biol (Camb). 2017 Dec 11;9(12):956-967.

Lorden ER, Miller KJ, Bashirov L, Ibrahim MM, Hammett E, Jung Y, Medina MA, Rastegarpour A, Selim MA, Leong KW, Levinson H. Mitigation of hypertrophic scar contraction via an elastomeric biodegradable scaffold.  Biomaterials. 2015 Mar;43:61-70.

Park JS, Suryaprakash S, Lao YH, Leong KW. Engineering mesenchymal stem cells for regenerative medicine and drug delivery.  Methods. 2015 Aug;84:3-16.

Lao YH, Phua KK, Leong KW. Aptamer nanomedicine for cancer therapeutics: barriers and potential for translation.  ACS Nano. 2015 Mar 24;9(3):2235-54.

Kulangara K, Adler AF, Wang H, Chellappan M, Hammett E, Yasuda R, Leong KW. The effect of substrate topography on direct reprogramming of fibroblasts to induced neurons. Biomaterials. 2014 Jul;35(20):5327-36.

Chakraborty S, Ji H, Kabadi AM, Gersbach CA, Christoforou N, Leong KW. A CRISPR/Cas9-based system for reprogramming cell lineage specification. Stem Cell Reports. 2014 Dec 9;3(6):940-7.