Kam Leong

Kam Leong


Samuel Y. Sheng Professor of Biomedical Engineering


Department of Biomedical Engineering
Department of Systems Biology

Kam Leong is the Samuel Y. Sheng Professor of Biomedical Engineering at Columbia University, and holds an Interdisciplinary Faculty position in the Department of Systems Biology. He is a pioneer in developing multifunctional nanoscale technologies for delivering drugs, antigens, proteins, siRNA, and DNA to cells. Innovations in the Leong Lab include biomaterials such as electrospun nanofibers for controlled release and tissue engineering, synthesis of biocompatible and near-infrared-emitting quantum dots, nucleic acid-binding polymers, and microfluidic platforms for nanomedicine. He has also designed nonviral gene delivery mechanisms for hemophilia treatment, genetic immunization, and cellular reprogramming. His recent work has focused on directly reprogramming adult cells from one lineage to another without going through the intermediate pluripotent state. His lab is particularly interested in how such approaches, based in tissue engineering and regenerative medicine, could offer new strategies for treating neurodegenerative disorders such as Alzheimer’s and Parkinson’s diseases.

Dr. Leong is internationally recognized as a leader in the development of nanoscale therapeutics. In 2013 he was elected a Member of the USA National Academy of Engineering and a Member of the USA National Academy of Inventors. 

More News


A Jack of All Trades: An Interview with Kam Leong
The biomedical engineer explains how nanotechnologies he has developed could support systems biology research and why interdisciplinary collaboration is so important to science and engineering today.
Department of Systems Biology Opens New Biotechnology Development Hub
The new space will promote the design of new experimental methods for studying biological systems, and enable an expansion of the Columbia Genome Center's next-generation sequencing capabilities.
Faculty Members Join Department of Systems Biology and C2B2
Kam Leong (Biomedical Engineering) has joined the Department as an interdisciplinary faculty member, while Yaniv Erlich (Computer Science) and Guy Sella (Biological Sciences) bring new expertise to C2B2.