Peter Sims

Selected Publications

Martuscello RT, Kerridge CA, Chatterjee D, Hartstone WG, Kuo SH, Sims PA, Louis ED, Faust PL. Gene expression analysis of the cerebellar cortex in essential tremor. Neurosci Lett. 2019 Nov 7:134540. doi: 10.1016/j.neulet.2019.134540.

Szabo PA, Levitin HM, Miron M, Snyder ME, Senda T, Yuan J, Cheng YL, Bush EC, Dogra P, Thapa P, Farber DL, Sims PA. Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease. Nat Commun. 2019 Oct 17;10(1):4706. doi: 10.1038/s41467-019-12464-3.

Sheth RU, Li M, Jiang W, Sims PA, Leong KW, Wang HH. Spatial metagenomic characterization of microbial biogeography in the gut. Nat Biotechnol. 2019 Aug;37(8):877-883. doi: 10.1038/s41587-019-0183-2. Epub 2019 Jul 22.

Louis ED, Kerridge CA, Chatterjee D, Martuscello RT, Diaz DT, Koeppen AH, Kuo SH, Vonsattel JG, Sims PA, Faust PL. Contextualizing the pathology in the essential tremor cerebellar cortex: a patholog-omics approach. Acta Neuropathol. 2019 Nov;138(5):859-876. doi: 10.1007/s00401-019-02043-7.

Juliano J, Gil O, Hawkins-Daarud A, Noticewala S, Rockne RC, Gallaher J, Massey SC, Sims PA, Anderson ARA, Swanson KR, Canoll P. Comparative dynamics of microglial and glioma cell motility at the infiltrative margin of brain tumours. J R Soc Interface. 2018 Feb;15(139).

Kiryluk K, Bomback AS, Cheng YL, Xu K, Camara PG, Rabadan R, Sims PA, Barasch J. Precision Medicine for Acute Kidney Injury (AKI): Redefining AKI by Agnostic Kidney Tissue Interrogation and Genetics. Semin Nephrol. 2018 Jan;38(1):40-51.

Yuan J, Sims PA. SPOTs fill a major gap in RNA quantification. Nat Methods. 2017 Nov 30;14(12):1137-1138.

Bush, E.C., Ray, F., Alvarez, M., Realubit, R., Li, H., Karan, C., Califano, A., Sims, P.A. PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens. Nature Communications. 2017 Jul 24.

Pan, Y., Bush, E.C., Toonen, J.A., Ma, Y., Solga, A.C., Sims, P.A., Gutmann, D.H. Whole tumor RNA-sequencing and deconvolution reveal a clinically prognostic PTEN/PI3K-regulated glioma transcriptional signature. Oncotarget. 2017 Apr 18.

Men Y, Fu Y, Chen Z, Sims PA, Greenleaf WJ, Huang Y. Digital polymerase chain reaction in an array of femtoliter polydimethylsiloxane microreactors. Anal Chem. 2012 May 15;84(10):4262-6.

Shiroguchi K, Jia TZ, Sims PA, Xie XS. Digital RNA sequencing minimizes sequence-dependent bias and amplification noise with single molecule barcodes. Proc Natl Acad Sci U S A. 2012 Jan 24; 109 (4): 1347-1352.

Sims PA, Greenleaf WJ, Duan H, Xie XS. Fluorogenic DNA sequencing in PDMS microreactors. Nat Methods. 2011 Jun 12;8(7):575-80.

Sims PA, Xie XS. Probing dynein and kinesin stepping with mechanical manipulation in a living cell. Chemphyschem. 2009 Jul 13;10(9-10):1511-6.

Nan X, Sims PA, Xie XS. Organelle tracking in a living cell with microsecond time resolution and nanometer spatial precision. Chemphyschem. 2008 Apr 4;9(5):707-12.