Richard Mann

Selected Publications

Kribelbauer JF, Lu XJ, Rohs R, Mann RS, Bussemaker HJ. Toward a Mechanistic Understanding of DNA Methylation Readout by Transcription Factors. J Mol Biol. 2019 Nov 2. pii: S0022-2836(19)30617-5. doi: 10.1016/j.jmb.2019.10.021.

Howard CE, Chen CL, Tabachnik T, Hormigo R, Ramdya P, Mann RS. Serotonergic Modulation of Walking in Drosophila. Curr Biol. 2019 Dec 16;29(24):4218-4230.e8. doi: 10.1016/j.cub.2019.10.042. 

Rao S, Chiu TP, Kribelbauer JF, Mann RS, Bussemaker HJ, Rohs R. Systematic prediction of DNA shape changes due to CpG methylation explains epigenetic effects on protein-DNA binding. Epigenetics Chromatin. 2018 Feb 6;11(1):6.

Voutev R, Mann RS. Robust ΦC31-Mediated Genome Engineering in Drosophila melanogaster Using Minimal attP/attB Phage Sites. G3 (Bethesda). 2018 Mar 9. pii: g3.200051.2018.

Requena D, Álvarez JA, Gabilondo H, Loker R, Mann RS, Estella C. Origins and Specification of the Drosophila Wing. Curr Biol. 2017 Dec 18;27(24):3826-3836.e5. Epub 2017 Dec 7.

Chiu TP, Rao S, Mann RS, Honig B, Rohs R. Genome-wide prediction of minor-groove electrostatic potential enables biophysical modeling of protein-DNA binding. Nucleic Acids Res. 2017 Dec 1.

Delker RK, Mann RS. From Reductionism to Holism: Toward a More Complete View of Development Through Genome Engineering. Adv Exp Med Biol. 2017 Nov 13;1016:45-74.

Kribelbauer JF, Laptenko O, Chen S, Martini GD, Freed-Pastor WA, Prives C, Mann RS, Bussemaker HJ. Quantitative Analysis of the DNA Methylation Sensitivity of Transcription Factor Complexes. Cell Rep. 2017 Jun 13.Shazman S, Lee H, Socol Y, Mann RS, Honig B. OnTheFly: a database of Drosophila melanogaster transcription factors and their binding sites. Nucleic Acids Res. 2014 Jan;42:D167-71. 

Slattery M, Riley T, Liu P, Abe N, Gomez-Alcala P, Dror I, Zhou T, Rohs R, Honig B, Bussemaker HJ, Mann RS. Cofactor binding evokes latent differences in DNA binding specificity between Hox proteins . Cell. 2011 Dec 9;147(6):1270-82.

Jory A, Estella C, Giorgianni MW, Slattery M, Laverty TR, Rubin GM, Mann RS. A survey of 6,300 genomic fragments for cis-regulatory activity in the imaginal discs of Drosophila melanogaster. Cell Rep. 2012 Oct 11. pii: S2211-1247(12)00291-4. 

Mendes, C, Bartos, I, Akay, T, Marka, S and Mann RS. Quantification of gait parameters in freely walking wild type and sensory deprived Drosophila melanogaster . eLife 2013:e00231. 

Slattery M, Voutev R., Ma L., Negre N. White KP, Mann RS.  Divergent transcriptional regulatory logic at the intersection of tissue growth and developmental patterning.  PLoS Genet. 2013;9(9):e1003753. 

Rohs R, West S, Sosinsky A, Liu P, Mann RS, Honig, B. The role of DNA shape in protein-DNA recognition . Nature. 2009 Oct 29;461(7268):1248-53.

Joshi R, Passner J, Rohs R, Jain R, Sosinsky A, Crickmore MA, Jacob V, Aggarwal AK, Honig B, Mann, RS. Functional specificity of a Hox protein mediated by the recognition of minor groove structure .Cell. 2007 Nove 2;131(3):530-43. 

Sosinsky A, Honig B, Mann RS, Califano A. Discovering transcriptional regulatory regions in Drosophila by a nonalignment method for phylogenetic footprinting . Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6305-10.