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The John Simon Guggenheim Foundation has named Harmen Bussemaker, Associate Professor in Columbia's Department of Biological Sciences, as one of its 2010 Fellows. The award supports a project titled "Deciphering the language of gene expression regulation," in which Dr. Bussemaker will combine methods from biophysics and genetics in order to predict the behavior of gene regulatory networks, and test these predictions using wet lab experiments. Guggenheim Fellows are appointed on the basis of impressive achievement in the past and exceptional promise for future accomplishment. Click here to learn more.

Harmen Bussemaker, Associate Professor in Columbia's Department of Biological Sciences, was one of this year's recipients of the Lenfest Distinguished Columbia Faculty Award. The awards are given annually to faculty of unusual merit across a range of professorial activities — including scholarship, University citizenship, and professional involvement — with a primary emphasis on the instruction and mentoring of undergraduate and graduate students. Click here to learn more.

Andrea Califano, Professor of Biomedical Informatics, co-Director of the Center for Computational Biology and Bioinformatics, and Director of the National Center for the Multiscale Analysis of Genetic and Cellular Networks has been appointed for a 5 year term to the National Cancer Institute (NCI) Board of Scientific Advisors. The NCI Board of Scientific Advisors provide scientific advice on a wide variety of matters concerning scientific program policy, progress and future direction of the NCI’s extramural research programs, and concept review of extramural program initiatives.

At the 2008 Annual Meeting of the cancer Biomedical Informatics Grid (caBIG™) initiative, members of the C2B2 software development team were recognized with awards for their technical achievements and contributions to the program, including their work in defining standards for the execution of bioinformatics workflows on caGrid (the grid infrastructure of caBIG) and in interfacing caGrid with TeraGrid, one of the largest national computational grid networks.

The Center for Computational Biology and Bioinformatics (C2B2), in collaboration with the Broad Institute of MIT and Harvard, has a received a 3-year award from the National Cancer Institute to establish and operate the Molecular Analysis Tools Knowledge Center of the cancer Biomedical Informatics Grid (caBIG™) initiative. The mission of the Knowledge Center is to promote the adoption of caBIG™ technologies aiming to facilitate the discovery of the next generation of cancer diagnostics and therapeutics which will help realize the vision of molecular and personalized medicine. geWorkbench, the bioinformatics platform of the MAGNet Center, will be one of the tools supported by the Knowledge Center.

The caBIG™ initiative, overseen by the NCI Center for Biomedical Informatics and Information Technology, was conceived to advance basic and clinical research on cancer and improve clinical outcomes for patients. Information such as patient registries, tissue management data, and study results can be uploaded to the grid-based system.

Barry Honig, PhD, professor of biochemistry & molecular biophysics and Director of C2B2, was inducted into the American Academy of Arts & Sciences in an October 6 ceremony in Cambridge, Massachusetts. The Academy is an independent research center conducting multidisciplinary studies of problems in science, technology, and global security; social policy and American institutions; the humanities and culture; and education.

C2B2 has been awarded a contract to serve as the Data Analysis and Coordination Center for the International Serious Adverse Event Consortium (iSAEC). iSAEC is a nonprofit organization comprising leading pharmaceutical companies and academic institutions with scientific and strategic input from the U.S. Food and Drug Administration (FDA). Using the power of whole genome association (WGA) studies, iSAEC aims to (i) identify and validate DNA-variants useful in predicting the risk of drug-related serious adverse events, and (ii) make such discoveries freely available to the research community for further investigations. C2B2 will provide  computational infrastructure for the storage and analysis of the WGA data as well as information systems for the dissemination of the analysis results to the public.

Dana Pe'er has been presented with the 2007 NIH Director's New Innovator Award (http://www.nih.gov/news/pr/sep2007/od-18a.htm). Part of an NIH Roadmap for Medical Research initiative, this award recognizes outstanding scientists who are "well-positioned to make significant — and potentially transformative — discoveries in a variety of areas.”

This award, proposed by NIH Director, Elias A. Zerhoni, MD was created to help new scientists fund highly innovative approaches to major research challenges that could lead to significant medical advances.

Dr. Pe'er is assistant professor of biological sciences at Columbia University, a member of the Center for Computational Biology and Bioinformatics and an investigator at the MAGNet Center. She utilizes computational and biotechnology approaches to understand how a cell’s regulatory network processes signals and how the signal processing goes wrong in cancer.

geWorkbench Wins Award

geWorkbench, the bioinformatics platform of the MAGNet Center, was recognized with an excellence award during the 2007 annual meeting of the cancer Biomedical Informatics Grid (caBIG) initiative. The geWorkbench project team was sited for "excellence in the design, planning and implementation of one of the first unrestricted open-source software projects from integrative genomics analysis."