Laura Landweber

Laura Landweber


Professor, Biochemistry and Molecular Biophysics, and Biological Sciences


Department of Biochemistry and Molecular Biophysics
Department of Biological Sciences
Department of Systems Biology
Center for Computational Biology and Bioinformatics


Work: (212) 305-3898

Laura Landweber is a professor in the Department of Biochemistry and Molecular Biophysics, Department of Biological Sciences, and the Department of Systems Biology.

The Landweber Lab investigates RNA-mediated epigenetics and genome reorganization during development and evolution.

Dr. Landweber earned her AB in Molecular Biology from Princeton University, and her PhD from Harvard University. She was faculty at Princeton for 22 years before moving to Columbia in 2016. Her awards include a Harvard University Junior Fellowship, Burroughs Wellcome Fund and Sigma Xi New Investigator Awards, an NSF Career Award in Computational Biology, the Blavatnik Award for Young Scientists from The New York Academy of Sciences, and a Guggenheim Fellowship.

More News


Laura Landweber, PhD, receives award from the National Institute of General Medical Sciences
Laura Landweber, PhD, will receive $3,858,485 over five years from the National Institute of General Medical Sciences for "Understanding Complex Genome Editing and RNA Biology in Oxytricha."
These Creatures Are Helping Us Understand Our Genome
A new study, led by Laura Landweber, PhD, of a single-celled eukaryote with 16,000 tiny chromosomes may shed light on a recently discovered feature of the human genome. Methyladenine, or 6mA—a modification of DNA common in Oxytricha trifallax—has only recently been found in multicellular organisms, with some studies suggesting a role in human disease and development. Finding the enzymes that lay down the methyl marks will be critical to understanding what 6mA is doing in Oxytricha and other organisms. The new research will be published June 13 in Cell.
Q+A with Dr. Laura Landweber
Laura Landweber, PhD, loves a challenge. So it’s no surprise that she has built a scientific career unraveling the hows and whys of a unique single-cell organism known for its biological complexity. Oxytricha trifallax is a microbial organism that is prevalent in ponds, feeds on algae and has a highly complex genome architecture, making it an attractive, albeit challenging, model organism to study. Several of the basic biology discoveries made in Oxytricha have been shown to extend to other organisms.