The MAGNet newsletter is a free annual publication that highlights the Center's activities. For members of the scientific community, this provides an opportunity to discover how the tools developed by the Center are used to address real biological questions. In addition to contributions by MAGNet investigators, several issues have also included an article by an invited author.


MAGNet Newsletter 2014

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Spring 2014 - Featured Articles

Cross-Species Computational Analysis Identifies a Synergistic Interaction that Drives Prostate Cancer Malignancy 
Cory Abate-Shen, Andrea Califano, Michael Shen

A Topological Approach for Characterizing Evolution 
Kevin Emmett, Raul Rabadan

A Global View of Tumor-Induced Gene Expression Changes in Human Metabolism 
Dennis Vitkup


MAGNet Newsletter 2013

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Spring 2013 - Featured Articles

PrePPI: A Novel Structure-Based Method for Predicting Protein-Protein Interactions 
Barry Honig

An Integrative Genomics Approach to Define RNA Regulatory Networks 
Chaolin Zhang

From Genome-Scale Sequencing to Angstrom-Scale Insights: The Enzyme DNase I Reveals Its True Colors 
Harmen J. Bussemaker


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Spring 2012 - Featured Articles

A Mesenchymal Transition Signature Present in Invasive Solid Cancers 
Dimitris Anastassiou

Discovering the Regulatory Programs Underlying Mammalian Transcript Stability 
Hani Goodarzi & Saeed Tavazoie

Mapping the miRNA Regulatory Network in Glioblastoma 
Pavel Sumazin & Andrea Califano


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Spring 2011 - Featured Articles

Interrogating Molecular Pathways of Prostate Tumorigenesis in Mice and Men 
Cory Abate-Shen & Michael M. Shen

The Origin and Evolution of a Pandemic Virus 
Zachary Carpenter, Carlos Hernandez, Joseph Chan, Raul Rabadan

The Transcriptional Network for Mesenchymal Transformation of Brain Tumours 
Andrea Califano


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Spring 2010 - Featured Articles

Structural Organization, Evolution, and Heterogeneous Activation of a Bacterial Sporulation Network 
Dennis Vitkup

Breaking the Code of Non-coding DNA in the Human Genome 
Tom Tullius

The Family of Man: Methods and Applications for Discovering Shared Ancestry among Purported Unrelateds 
Itsik Pe'er


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Winter 2009 - Featured Articles

Three R's of Computer Assisted Biomedical Discovery: Reading, Reasoning and Reporting 
Hannah Tipney & Lawrence Hunter

Dissecting Transcription Factor Function on Multiple Scales Biophysics, and Computers 
Harmen J. Bussemaker

Making Sense of Transcription Factor Specificities, or How to Grow Legs in Strange Places: a Collaboration between Flies, Biophysics, and Computers 
Richard S. Mann & Barry Honig


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Winter 2008 - Featured Articles

Understanding Cadherin Specificity in the Development of Multicellular Structures: a Combined Experimental and Computational Theory 
Lawrence Shapiro & Barry Honig

Mapping the Transcription Factor Modulator Repertoire in Human B Lymphocytes 
Andrea Califano & Riccardo Dalla-Favera

National Centers for Biomedical Computing and Related Activities at NIH 
Dan Gallahan