Search Publications
2026 Publications
. 2026.
Multiple molecular and cellular properties jointly affect protein and site-specific evolutionary rates..
bioRxiv : the preprint server for biology.
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. 2026.
Onconeural antigen NOVA1 dysregulates RNA alternative splicing in breast cancer..
RNA (New York, N.Y.).
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. 2026.
A forward genetic screen identifies Sirtuin1 as a driver of neuroendocrine prostate cancer..
The Journal of experimental medicine.
223
(7)
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. 2026.
Paired Tumor Biopsies Reveal Spatiotemporal Myeloid Remodeling After Local Chemotherapy in Glioblastoma..
bioRxiv : the preprint server for biology.
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. 2026.
Foundation models and deep learning for cancer drug response prediction: a framework for data, metrics, and validation..
Briefings in bioinformatics.
27
(3)
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. 2026.
Fast and Ultra-Capable Protein Design: Advancing the Frontier Through Atomistic SE(3)-Equivariance with Genie 3..
bioRxiv : the preprint server for biology.
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. 2026.
Modeling patient variants of and results in distinct forms of congenital diaphragmatic hernia in mice..
bioRxiv : the preprint server for biology.
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. 2026.
The genetic landscape of antibiotic sensitivity in ..
Science advances.
12
(19)
:eaeb9875
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. 2026.
A functional investigation of antibody Fc-FcRn variant binding guided by free energy perturbation methods..
bioRxiv : the preprint server for biology.
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. 2026.
Toward life with a 19-amino acid alphabet through generative artificial intelligence design..
Science (New York, N.Y.).
392
(6797)
:eaeb5171
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. 2026.
Molecular dynamics simulations of intrinsically disordered protein regions enable biophysical interpretation of variant-effect predictors..
HGG advances.
7
(3)
:100618
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. 2026.
Systematic design of combination therapy by targeting master regulators of coexisting diffuse midline glioma cell states..
Nature genetics.
58
(5)
:1112-1125
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. 2026.
Reply to Du: Differences in experimental setting make validation harder..
American journal of obstetrics & gynecology MFM.
8
(4)
:101900
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. 2026.
End-to-end evaluation of pipelines for metagenome-assembled genomes reveals hidden performance gaps..
bioRxiv : the preprint server for biology.
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. 2026.
Combining structural modeling and deep learning to calculate the E. coli protein interactome and functional networks..
Nature communications.
17
(1)
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. 2026.
GREmLN: A Cellular Graph Structure Aware Transcriptomics Foundation Model..
bioRxiv : the preprint server for biology.
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. 2026.
Proteome-wide prediction of interactions between structured domains and peptide motifs reveals functionally coherent subnetworks..
Proceedings of the National Academy of Sciences of the United States of America.
123
(15)
:e2527957123
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. 2026.
AlphaFold as a prior: experimental structure determination conditioned on a pretrained neural network..
Nature methods.
23
(4)
:785-795
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. 2026.
Exon inclusion signatures enable accurate estimation of splicing factor activity..
Nature communications.
17
(1)
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. 2026.
Exon inclusion signatures enable accurate estimation of splicing factor activity..
Nature communications.
17
(1)
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. 2026.
Dissociable perfusion chip (DPC): perfusable microfluidic chip for single-cell screening of anti-cancer drugs in live glioblastoma explants..
Lab on a chip.
26
(7)
:2266-2280
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. 2026.
PrePPI - Structure-based Prediction of Protein-protein Interactomes and Networks..
Journal of molecular biology.
:169735
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. 2026.
A generalizable cross-continent prediction of esophageal squamous cell carcinoma using the oral microbiome..
Communications medicine.
6
(1)
▶ Go to Pubmed
. 2026.
Single-cell RNA sequencing of adenoid cystic carcinoma of the breast reveals cellular heterogeneity and tumor microenvironment features..
BMC medical genomics.
19
(1)
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. 2026.
Neoadjuvant Fc-enhanced anti-CTLA-4 targets Tregs to augment androgen deprivation in high-risk prostate cancer: A randomized phase I trial..
Cell reports. Medicine.
7
(3)
:102638
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. 2026.
CLADES - Contrastive Learning Augmented DifferEntial Splicing with Orthologous Positive Pairs..
bioRxiv : the preprint server for biology.
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. 2026.
A neuron type-specific microexon in Ank3/ankyrin-G modulates calcium activity and neuronal excitability..
Nature communications.
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. 2026.
A neuron type-specific microexon in Ank3/ankyrin-G modulates calcium activity and neuronal excitability..
Nature communications.
17
(1)
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. 2026.
IDH-mutant inhibitors enhance the sensitivity of IDH1-mutant gliomas to cysteine-methionine deprivation and ferroptosis..
bioRxiv : the preprint server for biology.
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. 2026.
Pan-cancer inference and validation of hypermorphic, hypomorphic and neomorphic mutations..
Nature genetics.
58
(2)
:329-340
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. 2026.
Topology-Based Biomarkers Accurately Predict Breast Cancer Outcome and Survival..
Cancer research.
86
(8)
:2078-2093
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. 2026.
Machine learning to infer neurocognitive testing scores among adolescents and young adults with congenital heart disease..
Communications medicine.
6
(1)
▶ Go to Pubmed
. 2026.
Publisher Correction: Deciphering the role of complement system genes in pancreatic cancer susceptibility and prognosis..
Nature communications.
17
(1)
:1216
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. 2026.
Protein language models trained on biophysical dynamics inform mutation effects..
Proceedings of the National Academy of Sciences of the United States of America.
123
(4)
:e2530466123
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. 2026.
MYRF controls mesothelium specification, signaling, and plasticity in lung development..
Developmental cell.
61
(3)
:536-552.e4
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. 2026.
Mapping kinase-dependent tumor immune adaptation with multiplexed single-cell CRISPR screens..
bioRxiv : the preprint server for biology.
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. 2026.
A transposase-derived gene required for human brain development..
Science advances.
12
(3)
:eadv7530
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. 2026.
Visualization and quantification of rDNA instabilities in mammalian cells and mouse models..
Nucleic acids research.
54
(2)
▶ Go to Pubmed
. 2026.
Antisense oligonucleotides to KIF1A polymorphisms expand targets and rescue patient-derived neurons in vitro..
Nature communications.
17
(1)
:1109
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. 2026.
Mapping isoforms and regulatory mechanisms from spatial transcriptomics data with SPLISOSM..
Nature biotechnology.
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. 2026.
Efficient algorithms for simulating sequences along a phylogenetic tree..
Bioinformatics (Oxford, England).
42
(1)
▶ Go to Pubmed
. 2026.
Mismatch repair deficiency drives malignant progression and alters the tumor immune microenvironment in glioblastoma models..
The Journal of clinical investigation.
136
(6)
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. 2026.
Tissue signatures of human macrophages during homeostasis and activation..
Journal of immunology (Baltimore, Md. : 1950).
215
(3)
▶ Go to Pubmed
. 2026.
Transcriptomic Plasticity Is a Hallmark of Metastatic Pancreatic Cancer..
Cancer research.
86
(7)
:1769-1796
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. 2026.
NSD2 targeting reverses plasticity and drug resistance in prostate cancer..
Nature.
649
(8095)
:216-226
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. 2026.
NSD2 targeting reverses plasticity and drug resistance in prostate cancer..
Nature.
649
(8095)
:216-226
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. 2026.
Lung tissue-resident memory T cells optimize protection by IL-10 regulation of innate immunity..
The Journal of experimental medicine.
223
(1)
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. 2026.
Lung tissue-resident memory T cells optimize protection by IL-10 regulation of innate immunity..
The Journal of experimental medicine.
223
(1)
▶ Go to Pubmed
. 2026.
LONP1 Variants Are Associated With Clinically Diverse Phenotypes..
Clinical genetics.
109
(3)
:437-457
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. 2026.
Planning and Analyzing a Low-Biomass Microbiome Study: A Data Analysis Perspective..
The Journal of infectious diseases.
233
(1)
:76-86
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