Search Publications

Anat Kreimer, Oren Litvin, Ke Hao, Cliona Molony, Dana Pe'er, Itsik Pe'er .  2012.   Inference of modules associated to eQTLs.. Nucleic Acids Res. 40 (13) :e98 Go to Pubmed
Yong Chen, Ren Sheng, Morten Källberg, Antonina Silkov, Moe Tun, Nitin Bhardwaj, Svetlana Kurilova, Randy Hall, Barry Honig, Hui Lu, Wonhwa Cho .  2012.   Genome-wide functional annotation of dual-specificity protein- and lipid-binding modules that regulate protein interactions.. Mol Cell. 46 (2) :226-37 Go to Pubmed
Pablo Meyer, Julia Hoeng, Jeremy Rice, Raquel Norel, Jörg Sprengel, Katrin Stolle, Thomas Bonk, Stephanie Corthesy, Ajay Royyuru, Manuel Peitsch, Gustavo Stolovitzky .  2012.   Industrial methodology for process verification in research (IMPROVER): toward systems biology verification.. Bioinformatics. 28 (9) :1193-201 Go to Pubmed
Eimear Kenny, Itsik Pe'er, Amir Karban, Laurie Ozelius, Adele Mitchell, Sok Ng, Monica Erazo, Harry Ostrer, Clara Abraham, Maria Abreu, Gil Atzmon, Nir Barzilai, Steven Brant, Susan Bressman, Edward Burns, Yehuda Chowers, Lorraine Clark, Ariel Darvasi, Dana Doheny, Richard Duerr, Rami Eliakim, Nir Giladi, Peter Gregersen, Hakon Hakonarson, Michelle Jones, Karen Marder, Dermot McGovern, Jennifer Mulle, Avi Orr-Urtreger, Deborah Proctor, Ann Pulver, Jerome Rotter, Mark Silverberg, Thomas Ullman, Stephen Warren, Matti Waterman, Wei Zhang, Aviv Bergman, Lloyd Mayer, Seymour Katz, Robert Desnick, Judy Cho, Inga Peter .  2012.   A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.. PLoS Genet. 8 (3) :e1002559 Go to Pubmed
Kresten Lindorff-Larsen, Paul Maragakis, Stefano Piana, Michael Eastwood, Ron Dror, David Shaw .  2012.   Systematic validation of protein force fields against experimental data.. PLoS One. 7 (2) :e32131 Go to Pubmed
Giusy Gatta, Teresa Palomero, Arianne Perez-Garcia, Alberto Ambesi-Impiombato, Mukesh Bansal, Zachary Carpenter, Kim De Keersmaecker, Xavier Sole, Luyao Xu, Elisabeth Paietta, Janis Racevskis, Peter Wiernik, Jacob Rowe, Jules Meijerink, Andrea Califano, Adolfo Ferrando .  2012.   Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL.. Nat Med. 18 (3) :436-40 Go to Pubmed
Andrew Kruse, Jianxin Hu, Albert Pan, Daniel Arlow, Daniel Rosenbaum, Erica Rosemond, Hillary Green, Tong Liu, Pil Chae, Ron Dror, David Shaw, William Weis, Jürgen Wess, Brian Kobilka .  2012.   Structure and dynamics of the M3 muscarinic acetylcholine receptor.. Nature. 482 (7386) :552-6 Go to Pubmed
Vladimir Trifonov, Laura Pasqualucci, Riccardo Dalla-Favera, Raul Rabadan .  2011.   Fractal-like distributions over the rational numbers in high-throughput biological and clinical data.. Sci Rep. 1 :191 Go to Pubmed
Kresten Lindorff-Larsen, Nikola Trbovic, Paul Maragakis, Stefano Piana, David Shaw .  2012.   Structure and dynamics of an unfolded protein examined by molecular dynamics simulation.. J Am Chem Soc. 134 (8) :3787-91 Go to Pubmed
Benjamin Greenbaum, Olive Li, Leo Poon, Arnold Levine, Raul Rabadan .  2012.   Viral reassortment as an information exchange between viral segments.. Proc Natl Acad Sci U S A. 109 (9) :3341-6 Go to Pubmed
María Martínez, Alberto Corradin, Ulf Klein, Mariano Alvarez, Gianna Toffolo, Barbara di Camillo, Andrea Califano, Gustavo Stolovitzky .  2012.   Quantitative modeling of the terminal differentiation of B cells and mechanisms of lymphomagenesis.. Proc Natl Acad Sci U S A. 109 (7) :2672-7 Go to Pubmed
Andrea Califano, Manolis Kellis, Gustavo Stolovitzky .  2012.   Preface: RECOMB Systems Biology, Regulatory Genomics, and DREAM 2011 special issue.. J Comput Biol. 19 (2) :101 Go to Pubmed
Xinan Yang, Kelly Regan, Yong Huang, Qingbei Zhang, Jianrong Li, Tanguy Seiwert, Ezra Cohen, Rosie Xing, Yves Lussier .  2012.   Single sample expression-anchored mechanisms predict survival in head and neck cancer.. PLoS Comput Biol. 8 (1) :e1002350 Go to Pubmed
Saurav Guha, Jeffrey Rosenfeld, Anil Malhotra, Annette Lee, Peter Gregersen, John Kane, Itsik Pe'er, Ariel Darvasi, Todd Lencz .  2012.   Implications for health and disease in the genetic signature of the Ashkenazi Jewish population.. Genome Biol. 13 (1) :R2 Go to Pubmed
Paola Nicoletti, Vassiliki Cartsos, Penelope Palaska, Yufeng Shen, Aris Floratos, Athanasios Zavras .  2012.   Genomewide pharmacogenetics of bisphosphonate-induced osteonecrosis of the jaw: the role of RBMS3.. The oncologist. 17 (2) :279-87 Go to Pubmed
Paola Nicoletti, Vassiliki Cartsos, Penelope Palaska, Yufeng Shen, Aris Floratos, Athanasios Zavras .  2012.   Genomewide pharmacogenetics of bisphosphonate-induced osteonecrosis of the jaw: the role of RBMS3.. Oncologist. 17 (2) :279-87 Go to Pubmed
Caroline Ferreira, James Chen, Jianrong Li, Kazuhiro Shimomura, Xinan Yang, Yves Lussier, Lawrence Pinto, Julian Solway .  2012.   Genetic interactions between chromosomes 11 and 18 contribute to airway hyperresponsiveness in mice.. PLoS One. 7 (1) :e29579 Go to Pubmed
Celine Lefebvre, Gabrielle Rieckhof, Andrea Califano .  2012.   Reverse-engineering human regulatory networks.. Wiley Interdiscip Rev Syst Biol Med. 4 (4) :311-25 Go to Pubmed
Panagiotis Ntziachristos, Aristotelis Tsirigos, Pieter Van Vlierberghe, Jelena Nedjic, Thomas Trimarchi, Maria Flaherty, Dolors Ferres-Marco, Vanina da Ros, Zuojian Tang, Jasmin Siegle, Patrik Asp, Michael Hadler, Isaura Rigo, Kim De Keersmaecker, Jay Patel, Tien Huynh, Filippo Utro, Sandrine Poglio, Jeremy Samon, Elisabeth Paietta, Janis Racevskis, Jacob Rowe, Raul Rabadan, Ross Levine, Stuart Brown, Francoise Pflumio, Maria Dominguez, Adolfo Ferrando, Iannis Aifantis .  2012.   Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia.. Nat Med. 18 (2) :298-301 Go to Pubmed
Alexander Eletsky, Donald Petrey, Qiangfeng Zhang, Hsiau-Wei Lee, Thomas Acton, Rong Xiao, John Everett, James Prestegard, Barry Honig, Gaetano Montelione, Thomas Szyperski .  2012.   Solution NMR structures reveal unique homodimer formation by a winged helix-turn-helix motif and provide first structures for protein domain family PF10771.. J Struct Funct Genomics. 13 (1) :1-7 Go to Pubmed
Dimitris Anastassiou, Viktoria Rumjantseva, Wei-Yi Cheng, Jianzhong Huang, Peter Canoll, Darrell Yamashiro, Jessica Kandel .  2011.   Human cancer cells express Slug-based epithelial-mesenchymal transition gene expression signature obtained in vivo.. BMC Cancer. 11 :529 Go to Pubmed
Kyle Chard, Michael Russell, Yves Lussier, Eneida Mendonça, Jonathan Silverstein .  2011.   A cloud-based approach to medical NLP.. AMIA Annu Symp Proc. 2011 :207-16 Go to Pubmed
David Borhani, David Shaw .  2012.   The future of molecular dynamics simulations in drug discovery.. J Comput Aided Mol Des. 26 (1) :15-26 Go to Pubmed
Yves Lussier, Rosie Xing, Joseph Salama, Nikolai Khodarev, Yong Huang, Qingbei Zhang, Sajid Khan, Xinan Yang, Michael Hasselle, Thomas Darga, Renuka Malik, Hanli Fan, Samantha Perakis, Matthew Filippo, Kimberly Corbin, Younghee Lee, Mitchell Posner, Steven Chmura, Samuel Hellman, Ralph Weichselbaum .  2011.   MicroRNA expression characterizes oligometastasis(es).. PLoS One. 6 (12) :e28650 Go to Pubmed
Anil Raj, Michael Dewar, Gustavo Palacios, Raul Rabadan, Christopher Wiggins .  2011.   Identifying hosts of families of viruses: a machine learning approach.. PLoS One. 6 (12) :e27631 Go to Pubmed
Xiangshu Jin, Melissa Walker, Klara Felsovalyi, Jeremie Vendome, Fabiana Bahna, Seetha Mannepalli, Filip Cosmanescu, Goran Ahlsen, Barry Honig, Lawrence Shapiro .  2012.   Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca²+-free interdomain linkers.. Proc Natl Acad Sci U S A. 109 (3) :E127-34 Go to Pubmed
Matthew Slattery, Todd Riley, Peng Liu, Namiko Abe, Pilar Gomez-Alcala, Iris Dror, Tianyin Zhou, Remo Rohs, Barry Honig, Harmen Bussemaker, Richard Mann .  2011.   Cofactor binding evokes latent differences in DNA binding specificity between Hox proteins.. Cell. 147 (6) :1270-82 Go to Pubmed
Alexander Gusev, M Shah, Eimear Kenny, A Ramachandran, Jennifer Lowe, Jacqueline Salit, C Lee, E Levandowsky, T Weaver, Q Doan, H Peckham, S McLaughlin, M Lyons, N Sheth V, Markus Stoffel, F De La Vega, Jeffrey Friedman, Jan Breslow, Itsik Pe'er .  2012.   Low-pass genome-wide sequencing and variant inference using identity-by-descent in an isolated human population.. Genetics. 190 (2) :679-89 Go to Pubmed
Ninad Dewal, Yang Hu, Matthew Freedman, Thomas Laframboise, Itsik Pe'er .  2012.   Calling amplified haplotypes in next generation tumor sequence data.. Genome Res. 22 (2) :362-74 Go to Pubmed
Peter Freddolino, Sasan Amini, Saeed Tavazoie .  2012.   Newly identified genetic variations in common Escherichia coli MG1655 stock cultures.. J Bacteriol. 194 (2) :303-6 Go to Pubmed
Aris Floratos, Barry Honig, Dana Pe'er, Andrea Califano .  2012.   Using systems and structure biology tools to dissect cellular phenotypes.. J Am Med Inform Assoc. 19 (2) :171-5 Go to Pubmed
Binquan Luan, Gustavo Stolovitzky, Glenn Martyna .  2012.   Slowing and controlling the translocation of DNA in a solid-state nanopore.. Nanoscale. 4 (4) :1068-77 Go to Pubmed
Davide Rossi, Silvia Rasi, Giulia Fabbri, Valeria Spina, Marco Fangazio, Francesco Forconi, Roberto Marasca, Luca Laurenti, Alessio Bruscaggin, Michaela Cerri, Sara Monti, Stefania Cresta, Rosella Famà, Lorenzo De Paoli, Pietro Bulian, Valter Gattei, Anna Guarini, Silvia Deaglio, Daniela Capello, Raul Rabadan, Laura Pasqualucci, Riccardo Dalla-Favera, Robin Foá, Gianluca Gaidano .  2012.   Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia.. Blood. 119 (2) :521-9 Go to Pubmed
Binquan Luan, Glenn Martyna, Gustavo Stolovitzky .  2011.   Characterizing and controlling the motion of ssDNA in a solid-state nanopore.. Biophys J. 101 (9) :2214-22 Go to Pubmed
Davide Rossi, Alessio Bruscaggin, Valeria Spina, Silvia Rasi, Hossein Khiabanian, Monica Messina, Marco Fangazio, Tiziana Vaisitti, Sara Monti, Sabina Chiaretti, Anna Guarini, Ilaria Del Giudice, Michaela Cerri, Stefania Cresta, Clara Deambrogi, Ernesto Gargiulo, Valter Gattei, Francesco Forconi, Francesco Bertoni, Silvia Deaglio, Raul Rabadan, Laura Pasqualucci, Robin Foá, Riccardo Dalla-Favera, Gianluca Gaidano .  2011.   Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness.. Blood. 118 (26) :6904-8 Go to Pubmed
Sasan Amini, Alison Hottes, Lincoln Smith, Saeed Tavazoie .  2011.   Fitness landscape of antibiotic tolerance in Pseudomonas aeruginosa biofilms.. PLoS Pathog. 7 (10) :e1002298 Go to Pubmed
Pavel Sumazin, Xuerui Yang, Hua-Sheng Chiu, Wei-Jen Chung, Archana Iyer, David Llobet-Navas, Presha Rajbhandari, Mukesh Bansal, Paolo Guarnieri, Jose Silva, Andrea Califano .  2011.   An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma.. Cell. 147 (2) :370-81 Go to Pubmed
Andrew Kuziemko, Barry Honig, Donald Petrey .  2011.   Using structure to explore the sequence alignment space of remote homologs.. PLoS Comput Biol. 7 (10) :e1002175 Go to Pubmed
Kivanç Birsoy, Ryan Berry, Tim Wang, Ozge Ceyhan, Saeed Tavazoie, Jeffrey Friedman, Matthew Rodeheffer .  2011.   Analysis of gene networks in white adipose tissue development reveals a role for ETS2 in adipogenesis.. Development. 138 (21) :4709-19 Go to Pubmed
Yufeng Shen, Yiwei Gu, Itsik Pe'er .  2011.   A hidden Markov model for copy number variant prediction from whole genome resequencing data.. BMC Bioinformatics. 12 Suppl 6 :S4 Go to Pubmed
Katia Basso, Lara Mussolin, Antonella Lettieri, Manisha Brahmachary, Wei Lim, Andrea Califano, Giuseppe Basso, Andrea Biondi, Giovanni Cazzaniga, Angelo Rosolen .  2011.   T-cell lymphoblastic lymphoma shows differences and similarities with T-cell acute lymphoblastic leukemia by genomic and gene expression analyses.. Genes Chromosomes Cancer. 50 (12) :1063-75 Go to Pubmed
Sabrina Iñigo, Mariano Alvarez, Bárbara Strasser, Andrea Califano, Pablo Cerdán .  2012.   PFT1, the MED25 subunit of the plant Mediator complex, promotes flowering through CONSTANS dependent and independent mechanisms in Arabidopsis.. Plant J. 69 (4) :601-12 Go to Pubmed
Alexander Gusev, Pier Palamara, Gregory Aponte, Zhong Zhuang, Ariel Darvasi, Peter Gregersen, Itsik Pe'er .  2012.   The architecture of long-range haplotypes shared within and across populations.. Mol Biol Evol. 29 (2) :473-86 Go to Pubmed
Andrea Califano .  2011.   Striking a balance between feasible and realistic biological models.. Sci Transl Med. 3 (103) :103ps39 Go to Pubmed
Eric Bishop, Remo Rohs, Stephen Parker, Sean West, Peng Liu, Richard Mann, Barry Honig, Thomas Tullius .  2011.   A map of minor groove shape and electrostatic potential from hydroxyl radical cleavage patterns of DNA.. ACS Chem Biol. 6 (12) :1314-20 Go to Pubmed
Santiago Vilar, Rave Harpaz, Herbert Chase, Stefano Costanzi, Raul Rabadan, Carol Friedman .  2011.   Facilitating adverse drug event detection in pharmacovigilance databases using molecular structure similarity: application to rhabdomyolysis.. J Am Med Inform Assoc. 18 Suppl 1 :i73-80 Go to Pubmed
Mukesh Bansal, Andrea Califano .  2012.   Genome-wide dissection of posttranscriptional and posttranslational interactions.. Methods Mol Biol. 786 :131-49 Go to Pubmed
Pablo Meyer, Leonidas Alexopoulos, Thomas Bonk, Andrea Califano, Carolyn Cho, Alberto de la Fuente, David de Graaf, Alexander Hartemink, Julia Hoeng, Nikolai Ivanov V, Heinz Koeppl, Rune Linding, Daniel Marbach, Raquel Norel, Manuel Peitsch, Jeremy Rice, Ajay Royyuru, Frank Schacherer, Jörg Sprengel, Katrin Stolle, Dennis Vitkup, Gustavo Stolovitzky .  2011.   Verification of systems biology research in the age of collaborative competition.. Nat Biotechnol. 29 (9) :811-5 Go to Pubmed
Robert Prill, Julio Saez-Rodriguez, Leonidas Alexopoulos, Peter Sorger, Gustavo Stolovitzky .  2011.   Crowdsourcing network inference: the DREAM predictive signaling network challenge.. Sci Signal. 4 (189) :mr7 Go to Pubmed
Adam Wolpaw, Kenichi Shimada, Rachid Skouta, Matthew Welsch, Uri Akavia, Dana Pe'er, Fatima Shaik, Chloe Bulinski, Brent Stockwell .  2011.   Modulatory profiling identifies mechanisms of small molecule-induced cell death.. Proc Natl Acad Sci U S A. 108 (39) :E771-80 Go to Pubmed
Laura Wingler, Virginia Cornish .  2011.   Reiterative Recombination for the in vivo assembly of libraries of multigene pathways.. Proc Natl Acad Sci U S A. 108 (37) :15135-40 Go to Pubmed
Marianna de Julio, Mariano Alvarez, Antonella Galli, Jianhua Chu, Sandy Price, Andrea Califano, Michael Shen .  2011.   Regulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signaling.. Development. 138 (18) :3885-95 Go to Pubmed
Sasan Amini, Saeed Tavazoie .  2011.   Antibiotics and the post-genome revolution.. Curr Opin Microbiol. 14 (5) :513-8 Go to Pubmed
Laura Pasqualucci, Vladimir Trifonov, Giulia Fabbri, Jing Ma, Davide Rossi, Annalisa Chiarenza, Victoria Wells, Adina Grunn, Monica Messina, Oliver Elliot, Joseph Chan, Govind Bhagat, Amy Chadburn, Gianluca Gaidano, Charles Mullighan, Raul Rabadan, Riccardo Dalla-Favera .  2011.   Analysis of the coding genome of diffuse large B-cell lymphoma.. Nat Genet. 43 (9) :830-7 Go to Pubmed
Yinghao Wu, Jeremie Vendome, Lawrence Shapiro, Avinoam Ben-Shaul, Barry Honig .  2011.   Transforming binding affinities from three dimensions to two with application to cadherin clustering.. Nature. 475 (7357) :510-3 Go to Pubmed
C Velez, Pier Palamara, J Guevara-Aguirre, L Hao, T Karafet, M Guevara-Aguirre, Alexander Pearlman, Carole Oddoux, M Hammer, Edward Burns, Itsik Pe'er, G Atzmon, Harry Ostrer .  2012.   The impact of Converso Jews on the genomes of modern Latin Americans.. Hum Genet. 131 (2) :251-63 Go to Pubmed
Antony Holmes, Alexander Hawson, Feng Liu, Carol Friedman, Hossein Khiabanian, Raul Rabadan .  2011.   Discovering disease associations by integrating electronic clinical data and medical literature.. PLoS One. 6 (6) :e21132 Go to Pubmed
Laura Patwa, Ting-Jia Fan, Sandrine Tchaptchet, Yang Liu, Yves Lussier, Balfour Sartor, Jonathan Hansen .  2011.   Chronic intestinal inflammation induces stress-response genes in commensal Escherichia coli.. Gastroenterology. 141 (5) :1842-51.e1-10 Go to Pubmed
Biji Mathew, Jeffrey Jacobson, Evgeny Berdyshev, Yong Huang, Xiaoguang Sun, Yutong Zhao, Lynnette Gerhold, Jessica Siegler, Carrie Evenoski, Ting Wang, Tong Zhou, Rafe Zaidi, Liliana Moreno-Vinasco, Robert Bittman, Chin Chen, Patrick LaRiviere, Saad Sammani, Yves Lussier, Steven Dudek, Viswanathan Natarajan, Ralph Weichselbaum, Joe Garcia .  2011.   Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs.. FASEB J. 25 (10) :3388-400 Go to Pubmed
Markus Fischer, Qiangfeng Zhang, Fabian Dey, Brian Chen, Barry Honig, Donald Petrey .  2011.   MarkUs: a server to navigate sequence-structure-function space.. Nucleic Acids Res. 39 (Web Server issue) :W357-61 Go to Pubmed
James Chen, Jianrong Li, Walter Stadler, Yves Lussier .  2011.   Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence.. J Am Med Inform Assoc. 18 (4) :392-402 Go to Pubmed
Giulia Fabbri, Silvia Rasi, Davide Rossi, Vladimir Trifonov, Hossein Khiabanian, Jing Ma, Adina Grunn, Marco Fangazio, Daniela Capello, Sara Monti, Stefania Cresta, Ernesto Gargiulo, Francesco Forconi, Anna Guarini, Luca Arcaini, Marco Paulli, Luca Laurenti, Luigi Larocca, Roberto Marasca, Valter Gattei, David Oscier, Francesco Bertoni, Charles Mullighan, Robin Foá, Laura Pasqualucci, Raul Rabadan, Riccardo Dalla-Favera, Gianluca Gaidano .  2011.   Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.. J Exp Med. 208 (7) :1389-401 Go to Pubmed
Enrico Tiacci, Vladimir Trifonov, Gianluca Schiavoni, Antony Holmes, Wolfgang Kern, Maria Martelli, Alessandra Pucciarini, Barbara Bigerna, Roberta Pacini, Victoria Wells, Paolo Sportoletti, Valentina Pettirossi, Roberta Mannucci, Oliver Elliott, Arcangelo Liso, Achille Ambrosetti, Alessandro Pulsoni, Francesco Forconi, Livio Trentin, Gianpietro Semenzato, Giorgio Inghirami, Monia Capponi, Francesco Di Raimondo, Caterina Patti, Luca Arcaini, Pellegrino Musto, Stefano Pileri, Claudia Haferlach, Susanne Schnittger, Giovanni Pizzolo, Robin Foá, Laurent Farinelli, Torsten Haferlach, Laura Pasqualucci, Raul Rabadan, Brunangelo Falini .  2011.   BRAF mutations in hairy-cell leukemia.. N Engl J Med. 364 (24) :2305-15 Go to Pubmed
Sarah Gilman, Ivan Iossifov, Dan Levy, Michael Ronemus, Michael Wigler, Dennis Vitkup .  2011.   Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses.. Neuron. 70 (5) :898-907 Go to Pubmed
Jiang Zhu, Yong Yu, Maximilian Ulbrich, Ming-hui Li, Ehud Isacoff, Barry Honig, Jian Yang .  2011.   Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach.. Proc Natl Acad Sci U S A. 108 (25) :10133-8 Go to Pubmed
Alexander Gusev, Eimear Kenny, Jennifer Lowe, Jacqueline Salit, Richa Saxena, Sekar Kathiresan, David Altshuler, Jeffrey Friedman, Jan Breslow, Itsik Pe'er .  2011.   DASH: a method for identical-by-descent haplotype mapping uncovers association with recent variation.. Am J Hum Genet. 88 (6) :706-17 Go to Pubmed
Qiangfeng Zhang, Lei Deng, Markus Fisher, Jihong Guan, Barry Honig, Donald Petrey .  2011.   PredUs: a web server for predicting protein interfaces using structural neighbors.. Nucleic Acids Res. 39 (Web Server issue) :W283-7 Go to Pubmed
Stefan Harrer, Philip Waggoner, Binquan Luan, Ali Afzali-Ardakani, Dario Goldfarb, Hongbo Peng, Glenn Martyna, Stephen Rossnagel, Gustavo Stolovitzky .  2011.   Electrochemical protection of thin film electrodes in solid state nanopores.. Nanotechnology. 22 (27) :275304 Go to Pubmed
Cynthia Rudin, David Waltz, Roger Anderson, Albert Boulanger, Ansaf Salleb-Aouissi, Maggie Chow, Haimonti Dutta, Philip Gross, Bert Huang, Steve Ierome, Delfina Isaac, Arthur Kressner, Rebecca Passonneau, Axinia Radeva, Leon Wu .  2012.   Machine learning for the New York City power grid.. IEEE Trans Pattern Anal Mach Intell. 34 (2) :328-45 Go to Pubmed
Jeremie Vendome, Shoshana Posy, Xiangshu Jin, Fabiana Bahna, Goran Ahlsen, Lawrence Shapiro, Barry Honig .  2011.   Molecular design principles underlying β-strand swapping in the adhesive dimerization of cadherins.. Nat Struct Mol Biol. 18 (6) :693-700 Go to Pubmed
Xiaoyuan Xie, Joshua Ho, Christian Murphy, Gail Kaiser, Baowen Xu, Tsong Chen .  2011.   Testing and Validating Machine Learning Classifiers by Metamorphic Testing.. J Syst Softw. 84 (4) :544-558 Go to Pubmed
Huning Dai, Christian Murphy, Gail Kaiser .  2010.   Configuration Fuzzing for Software Vulnerability Detection.. Proc Int Conf Availab Reliab Secur. :525-530 Go to Pubmed
Hoon Kim, John Watkinson, Dimitris Anastassiou .  2011.   Biomarker discovery using statistically significant gene sets.. J Comput Biol. 18 (10) :1329-38 Go to Pubmed
Xinan Yang, Jianrong Li, Younghee Lee, Yves Lussier .  2011.   GO-Module: functional synthesis and improved interpretation of Gene Ontology patterns.. Bioinformatics. 27 (10) :1444-6 Go to Pubmed
Dana Pe'er, Nir Hacohen .  2011.   Principles and strategies for developing network models in cancer.. Cell. 144 (6) :864-73 Go to Pubmed
Aaron Hoskins, Larry Friedman, Sarah Gallagher, Daniel Crawford, Eric Anderson, Richard Wombacher, Nicholas Ramirez, Virginia Cornish, Jeff Gelles, Melissa Moore .  2011.   Ordered and dynamic assembly of single spliceosomes.. Science. 331 (6022) :1289-95 Go to Pubmed
Laura Pasqualucci, David Dominguez-Sola, Annalisa Chiarenza, Giulia Fabbri, Adina Grunn, Vladimir Trifonov, Lawryn Kasper, Stephanie Lerach, Hongyan Tang, Jing Ma, Davide Rossi, Amy Chadburn, Vundavalli Murty V, Charles Mullighan, Gianluca Gaidano, Raul Rabadan, Paul Brindle, Riccardo Dalla-Favera .  2011.   Inactivating mutations of acetyltransferase genes in B-cell lymphoma.. Nature. 471 (7337) :189-95 Go to Pubmed
Younghee Lee, Jianrong Li, Eric Gamazon, James Chen, Anna Tikhomirov, Nancy Cox, Yves Lussier .  2010.   Biomolecular Systems of Disease Buried Across Multiple GWAS Unveiled by Information Theory and Ontology.. AMIA Jt Summits Transl Sci Proc. 2010 :31-5 Go to Pubmed
Tara Borlawsky, Jianrong Li, Lyudmila Shagina, Matthew Crowson, Yang Liu, Carol Friedman, Yves Lussier .  2010.   Evaluation of an Ontology-anchored Natural Language-based Approach for Asserting Multi-scale Biomolecular Networks for Systems Medicine.. AMIA Jt Summits Transl Sci Proc. 2010 :6-10 Go to Pubmed
Xinan Yang, Younghee Lee, Hong Fan, Xiao Sun, Yves Lussier .  2010.   Identification of common microRNA-mRNA regulatory biomodules in human epithelial cancers.. Chin Sci Bull. 55 (31) :3576-3589 Go to Pubmed
Oliver Harrison, Xiangshu Jin, Soonjin Hong, Fabiana Bahna, Goran Ahlsen, Julia Brasch, Yinghao Wu, Jeremie Vendome, Klara Felsovalyi, Cheri Hampton, Regina Troyanovsky, Avinoam Ben-Shaul, Joachim Frank, Sergey Troyanovsky, Lawrence Shapiro, Barry Honig .  2011.   The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins.. Structure. 19 (2) :244-56 Go to Pubmed
Julia Brasch, Oliver Harrison, Goran Ahlsen, Stewart Carnally, Robert Henderson, Barry Honig, Lawrence Shapiro .  2011.   Structure and binding mechanism of vascular endothelial cadherin: a divergent classical cadherin.. J Mol Biol. 408 (1) :57-73 Go to Pubmed
Caryn Shechtman, Annette Henneberry, Tracie Seimon, Arthur Tinkelenberg, Lisa Wilcox, Eunjee Lee, Mina Fazlollahi, Andrew Munkacsi, Harmen Bussemaker, Ira Tabas, Stephen Sturley .  2011.   Loss of subcellular lipid transport due to ARV1 deficiency disrupts organelle homeostasis and activates the unfolded protein response.. J Biol Chem. 286 (14) :11951-9 Go to Pubmed
Lixia Yao, Anna Divoli, Ilya Mayzus, James Evans, Andrey Rzhetsky .  2011.   Benchmarking ontologies: bigger or better?. PLoS Comput Biol. 7 (1) :e1001055 Go to Pubmed
Xiaoyuan Xie, Joshua Ho, Christian Murphy, Gail Kaiser, Baowen Xu, Tsong Chen .  2010.   Application of Metamorphic Testing to Supervised Classifiers.. Proc Int Conf Qual Softw. 2009 (2009) :135-144 Go to Pubmed
Yufeng Shen, Paola Nicoletti, Aris Floratos, Munir Pirmohamed, Mariam Molokhia, P Geppetti, S Benemei, B Giomi, D Schena, A Vultaggio, R Stern, M Daly, Sally John, M Nelson, Itsik Pe'er, International Consortium .  2012.   Genome-wide association study of serious blistering skin rash caused by drugs.. Pharmacogenomics J. 12 (2) :96-104 Go to Pubmed
Christian Murphy, Moses Vaughan, Waseem Ilahi, Gail Kaiser .  2010.   Automatic Detection of Previously-Unseen Application States for Deployment Environment Testing and Analysis.. Proc Int Workshop Autom Softw Test. 2010 :16-23 Go to Pubmed
Rave Harpaz, H Perez, Herbert Chase, Raul Rabadan, G Hripcsak, Carol Friedman .  2011.   Biclustering of adverse drug events in the FDA's spontaneous reporting system.. Clin Pharmacol Ther. 89 (2) :243-50 Go to Pubmed
Andrew Mugler, Boris Grinshpun, Riley Franks, Chris Wiggins .  2011.   Statistical method for revealing form-function relations in biological networks.. Proc Natl Acad Sci U S A. 108 (2) :446-51 Go to Pubmed
William Behnke-Parks, Jeremie Vendome, Barry Honig, Zoltan Maliga, Carolyn Moores, Steven Rosenfeld .  2011.   Loop L5 acts as a conformational latch in the mitotic kinesin Eg5.. J Biol Chem. 286 (7) :5242-53 Go to Pubmed
Uri Akavia, Oren Litvin, Jessica Kim, Felix Sanchez-Garcia, Dylan Kotliar, Helen Causton, Panisa Pochanard, Eyal Mozes, Levi Garraway, Dana Pe'er .  2010.   An integrated approach to uncover drivers of cancer.. Cell. 143 (6) :1005-17 Go to Pubmed
Eimear Kenny, Minseung Kim, Alexander Gusev, Jennifer Lowe, Jacqueline Salit, Gustav Smith, Sirisha Kovvali, Hyun Kang, Christopher Newton-Cheh, Mark Daly, Markus Stoffel, David Altshuler, Jeffrey Friedman, Eleazar Eskin, Jan Breslow, Itsik Pe'er .  2011.   Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population.. Hum Mol Genet. 20 (4) :827-39 Go to Pubmed
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