Randomly
Lead Investigator(s)Raul Rabadan

Randomly is a python package for denoising single-cell data using Random Matrix Theory.

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REDUCE Suite
Lead Investigator(s)Harmen Bussemaker

A set of software tools for modeling the regulation of gene expression by transcription factors (TF); includes MatrixREDUCE, LogoGenerator, and Transfactivity.

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Repertoire
Lead Investigator(s)Yufeng Shen

Scripts for analyzing T cell receptor repertoire sequencing data.

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SAVI
Lead Investigator(s)Raul Rabadan

A program for calling variants in high-throughput sequencing data, particularly paired tumor-normal samples.

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SCREEN
Lead Investigator(s)Barry Honig
A tool for identifying protein cavities and computing cavity attributes that can be applied for classification and analysis.
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scTDA
Lead Investigator(s)Raul Rabadan

An object-oriented python library for topological data analysis of high-throughput single-cell RNA-seq data.

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ShareViz
Lead Investigator(s)Itsik Pe'er

A tool for graphical visualization of hidden relatedness based on GERMLINE output.

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SIXPAC
Lead Investigator(s)Itsik Pe'er

An efficient, scalable search algorithm that finds synergy between pairs of physically unlinked SNPs (genome-wide) in large case-control datasets.

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Ska
Lead Investigator(s)Barry Honig

A program to compare and align protein structures.

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SkyLine
Lead Investigator(s)

A high-throughput pipeline for homology modeling of protein structures.

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Splicescope
Lead Investigator(s)Chaolin Zhang

A method to evaluate neuronal maturation based on alternative splicing profiles.

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SURFace
Lead Investigator(s)Barry Honig
Programs that calculate solvent accessible surface area and curvature-corrected solvent accessible surface area.
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T-profiler
Lead Investigator(s)Harmen Bussemaker

A web-based tool that uses the t-test to interpret genome-wide mRNA expression changes at the level of Gene Ontology categories or ChIP-based regulons.

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TARGet
Lead Investigator(s)Raul Rabadan

A light-weight application for reconstructing non-vertical evolutionary histories from sampled genetic sequences using persistent homology, a tool from topological data analysis.

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TEISER
Lead Investigator(s)Saeed Tavazoie

A de-novo motif discovery tool for finding informative structural elements in RNA.

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TOBI
Lead Investigator(s)Raul Rabadan

TOBI predicts somatic variants from .vcf or .bam input.

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TranscriptionDetector
Lead Investigator(s)Harmen Bussemaker

A tool for finding probes that measures significantly expressed loci in a genomic array experiment.

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