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. 2021.
Systematic dissection of σ sequence diversity and function in bacteria..
Cell reports.
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. 2021.
Cellular origins and lineage relationships of the intestinal epithelium..
American journal of physiology. Gastrointestinal and liver physiology.
321
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. 2021.
Protein-structure prediction revolutionized..
Nature.
596
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. 2021.
A persistent look at how tumours evade therapy..
Nature.
596
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. 2021.
Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2..
Genome Med.
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. 2021.
Protein structure prediction by AlphaFold2: are attention and symmetries all you need?.
Acta Crystallogr D Struct Biol.
77
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. 2021.
. 2021.
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Modeling metastasis in mice: a closer look..
Trends Cancer.
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. 2021.
High-Throughput Transcriptional Characterization of Regulatory Sequences from Bacterial Biosynthetic Gene Clusters..
ACS synthetic biology.
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. 2021.
. 2021.
Sorting of cadherin-catenin-associated proteins into individual clusters..
Proceedings of the National Academy of Sciences of the United States of America.
118
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. 2021.
Sorting of cadherin-catenin-associated proteins into individual clusters..
Proc Natl Acad Sci U S A.
118
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. 2021.
Molecular topography of an entire nervous system..
Cell.
184
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TGM4: an immunogenic prostate-restricted antigen..
J Immunother Cancer.
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. 2021.
Fusobacterium nucleatum secretes amyloid-like FadA to enhance pathogenicity..
EMBO reports.
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. 2021.
Dynamic landscape of protein occupancy across the Escherichia coli chromosome..
PLoS Biol.
19
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. 2021.
Phase I/II trial of ruxolitinib in combination with trastuzumab in metastatic HER2 positive breast cancer..
Breast Cancer Res Treat.
189
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. 2021.
. 2021.
. 2022.
iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4..
Nat Commun.
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. 2021.
Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations..
Cancer Cell.
39
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. 2021.
Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations..
Cancer cell.
39
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. 2021.
Targeting the T-Cell Lymphoma Epigenome Induces Cell Death, Cancer Testes Antigens, Immune-Modulatory Signaling Pathways..
Mol Cancer Ther.
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. 2021.
A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance..
Nature cancer.
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. 2020.
. 2020.
Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma..
Proc Natl Acad Sci U S A.
118
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. 2021.
Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages..
Cell.
184
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. 2021.
Machine learning in protein structure prediction..
Curr Opin Chem Biol.
65
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. 2021.
. 2021.
Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations..
Cancer Cell.
39
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:866-882.e11
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. 2021.
Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations..
Cancer cell.
39
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. 2021.
induces NF-κB signaling-driven peripheral T cell lymphoma..
Nat Cancer.
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. 2021.
Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts..
The Journal of clinical investigation.
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. 2020.
PDK1 Is Required for Maintenance of CD4 Foxp3 Regulatory T Cell Function..
J Immunol.
206
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. 2021.
. 2021.
Novel ultra-rare exonic variants identified in a founder population implicate cadherins in schizophrenia..
Neuron.
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. 2021.
Integrating 3D structural information into systems biology..
J Biol Chem.
296
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. 2021.
Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities..
Nature cancer.
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. 2021.
An expanded universe of cancer targets..
Cell.
184
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. 2021.
. 2021.
Functional interrogation of DNA damage response variants with base editing screens..
Cell.
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. 2021.
An Introduction to Whole-Metagenome Shotgun Sequencing Studies..
Methods Mol Biol.
2243
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. 2021.
Global Patterns of Recombination across Human Viruses..
Mol Biol Evol.
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. 2021.
Comprehensive characterization of protein-protein interactions perturbed by disease mutations..
Nat Genet.
53
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. 2021.
Computing the Role of Alternative Splicing in Cancer..
Trends Cancer.
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. 2021.
Prioritizing transcriptional factors in gene regulatory networks with PageRank..
iScience.
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. 2021.
The harsh microenvironment in early breast cancer selects for a Warburg phenotype..
Proceedings of the National Academy of Sciences of the United States of America.
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. 2021.
A modular master regulator landscape controls cancer transcriptional identity..
Cell.
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Robust direct digital-to-biological data storage in living cells..
Nature chemical biology.
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. 2021.
. 2021.
The UVSSA complex alleviates MYC-driven transcription stress..
J Cell Biol.
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-quinoline-benzenesulfonamide derivatives exert potent anti-lymphoma effect by targeting NF-κB..
iScience.
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. 2020.
. 2021.
. 2020.
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CRISPR RNA-guided integrases for high-efficiency, multiplexed bacterial genome engineering..
Nature biotechnology.
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. 2021.
CRISPR RNA-guided integrases for high-efficiency, multiplexed bacterial genome engineering..
Nature biotechnology.
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. 2021.
Genomic characterization of HIV-associated plasmablastic lymphoma identifies pervasive mutations in the JAK-STAT pathway..
Blood Cancer Discov.
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. 2020.
Functional redundancy of type I and type II receptors in the regulation of skeletal muscle growth by myostatin and activin A..
Proc Natl Acad Sci U S A.
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. 2020.
A Random Matrix Theory Approach to Denoise Single-Cell Data..
Patterns (N Y).
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. 2020.
Bipotent Progenitors Do Not Require Androgen Receptor for Luminal Specification during Prostate Organogenesis..
Stem Cell Reports.
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. 2020.
Integrating single-cell RNA-seq and imaging with SCOPE-seq2..
Scientific reports.
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. 2020.
Regulatory and evolutionary adaptation of yeast to acute lethal ethanol stress..
PLoS One.
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. 2020.
A map of tumor-host interactions in glioma at single-cell resolution..
GigaScience.
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. 2020.
. 2020.
High tumor mutational burden and T-cell activation are associated with long-term response to anti-PD1 therapy in Lynch syndrome recurrent glioblastoma patient..
Cancer Immunol Immunother.
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. 2021.
Exons as units of phenotypic impact for truncating mutations in autism..
Mol Psychiatry.
26
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. 2021.
Analysis of respiratory and systemic immune responses in COVID-19 reveals mechanisms of disease pathogenesis..
medRxiv : the preprint server for health sciences.
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. 2020.
Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state..
Nat Med.
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Beta-lactam-induced immediate hypersensitivity reactions: A genome-wide association study of a deeply phenotyped cohort..
The Journal of allergy and clinical immunology.
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Mutant SF3B1 promotes AKT- and NF-κB-driven mammary tumorigenesis..
J Clin Invest.
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SICaRiO: short indel call filtering with boosting..
Brief Bioinform.
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CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining..
Proc Natl Acad Sci U S A.
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CRISPR/Cas9-Mediated Point Mutation in Prolongs Protein Half-Life and Reverses Effects Allelic Loss..
Cancer Res.
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Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses..
Nat Biotechnol.
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Protecting Linear DNA Templates in Cell-Free Expression Systems from Diverse Bacteria..
ACS synthetic biology.
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. 2020.
. 2020.
Identifying the Potential Mechanism of Action of SNPs Associated With Breast Cancer Susceptibility With GVITamIN..
Front Bioeng Biotechnol.
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. 2020.
. 2020.
MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas..
Nat Commun.
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. 2020.
Identification of relevant genetic alterations in cancer using topological data analysis..
Nat Commun.
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Single-Cell Transcriptional Profiling of the Intestinal Epithelium..
Methods in molecular biology (Clifton, N.J.).
2171
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. 2020.
Impact of Fiber-Based Enteral Nutrition on the Gut Microbiome of ICU Patients Receiving Broad-Spectrum Antibiotics: A Randomized Pilot Trial..
Critical care explorations.
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. 2020.
Programmable CRISPR-Cas transcriptional activation in bacteria..
Molecular systems biology.
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. 2020.
The effect of short-course antibiotics on the resistance profile of colonizing gut bacteria in the ICU: a prospective cohort study..
Critical care (London, England).
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. 2020.