Search Publications

Michael Chait, Mine Yilmaz, Shanila Shakil, Amy Ku, Pranay Dogra, Thomas Connors, Peter Szabo, Joshua Gray, Steven Wells, Masaru Kubota, Rei Matsumoto, Maya Poon, Mark Snyder, Matthew Baldwin, Peter Sims, Anjali Saqi, Donna Farber, Stuart Weisberg .  2022.   Immune and epithelial determinants of age-related risk and alveolar injury in fatal COVID-19.. JCI insight. 7 (11) Go to Pubmed
Jose Cortes, Ioan Filip, Robert Albero, Juan Patiño-Galindo, Aidan Quinn, Wen-Hsuan Lin, Anouchka Laurent, Bobby Shih, Jessie Brown, Anisha Cooke, Adam Mackey, Jonah Einson, Sakellarios Zairis, Alfredo Rivas-Delgado, Maria Laginestra, Stefano Pileri, Elias Campo, Govind Bhagat, Adolfo Ferrando, Raul Rabadan, Teresa Palomero .  2022.   Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma.. Cell reports. 39 (3) :110695 Go to Pubmed
David Schoenfeld, Royce Zhou, Sakellarios Zairis, William Su, Nicole Steinbach, Deepti Mathur, Ankita Bansal, Alexis Zachem, Bertilia Tavarez, Dan Hasson, Emily Bernstein, Raul Rabadan, Ramon Parsons .  2022.   Loss of PBRM1 Alters Promoter Histone Modifications and Activates ALDH1A1 to Drive Renal Cell Carcinoma.. Mol Cancer Res. 20 (8) :1193-1207 Go to Pubmed
Shuwa Xu, Alina Sergeeva, Phinikoula Katsamba, Seetha Mannepalli, Fabiana Bahna, Jude Bimela, Lawrence Zipursky, Lawrence Shapiro, Barry Honig, Kai Zinn .  2022.   Affinity requirements for control of synaptic targeting and neuronal cell survival by heterophilic IgSF cell adhesion molecules.. Cell reports. 39 (1) :110618 Go to Pubmed
Shuwa Xu, Alina Sergeeva, Phinikoula Katsamba, Seetha Mannepalli, Fabiana Bahna, Jude Bimela, Lawrence Zipursky, Lawrence Shapiro, Barry Honig, Kai Zinn .  2022.   Affinity requirements for control of synaptic targeting and neuronal cell survival by heterophilic IgSF cell adhesion molecules.. Cell reports. 39 (1) :110618 Go to Pubmed
Jordan Metz, Nicholas Hornstein, Sohani Sharma, Jeremy Worley, Christian Gonzalez, Peter Sims .  2022.   High-throughput translational profiling with riboPLATE-seq.. Scientific reports. 12 (1) :5718 Go to Pubmed
Moritz Middelhoff, Giovanni Valenti, Lorenzo Tomassoni, Yosuke Ochiai, Bryana Belin, Ryota Takahashi, Ermanno Malagola, Henrik Nienhüser, Michael Finlayson, Yoku Hayakawa, Leah Zamechek, Bernhard Renz, Benedikt Westphalen, Michael Quante, Kara Margolis, Peter Sims, Pasquale Laise, Andrea Califano, Meenakshi Rao, Michael Gershon, Timothy Wang .  2022.   Adult enteric Dclk1-positive glial and neuronal cells reveal distinct responses to acute intestinal injury.. American journal of physiology. Gastrointestinal and liver physiology. 322 (6) :G583-G597 Go to Pubmed
Moritz Middelhoff, Giovanni Valenti, Lorenzo Tomassoni, Yosuke Ochiai, Bryana Belin, Ryota Takahashi, Ermanno Malagola, Henrik Nienhüser, Michael Finlayson, Yoku Hayakawa, Leah Zamechek, Bernhard Renz, Benedikt Westphalen, Michael Quante, Kara Margolis, Peter Sims, Pasquale Laise, Andrea Califano, Meenakshi Rao, Michael Gershon, Timothy Wang .  2022.   Adult enteric Dclk1-positive glial and neuronal cells reveal distinct responses to acute intestinal injury.. Am J Physiol Gastrointest Liver Physiol. 322 (6) :G583-G597 Go to Pubmed
Mark Snyder, Kaveh Moghbeli, Anna Bondonese, Andrew Craig, Iulia Popescu, Li Fan, Tracy Tabib, Robert Lafyatis, Kong Chen, Humberto Bittar, Elizabeth Lendermon, Joseph Pilewski, Bruce Johnson, Silpa Kilaru, Yingze Zhang, Pablo Sanchez, Jonathan Alder, Peter Sims, John McDyer .  2022.   Modulation of tissue resident memory T cells by glucocorticoids after acute cellular rejection in lung transplantation.. The Journal of experimental medicine. 219 (4) Go to Pubmed
Aleksandar Obradovic, Diana Graves, Michael Korrer, Yu Wang, Sohini Roy, Abdullah Naveed, Yaomin Xu, Adam Luginbuhl, Joseph Curry, Michael Gibson, Kamran Idrees, Paula Hurley, Peng Jiang, Shirley Liu, Ravindra Uppaluri, Charles Drake, Andrea Califano, Young Kim .  2022.   Immunostimulatory Cancer-Associated Fibroblast Subpopulations Can Predict Immunotherapy Response in Head and Neck Cancer.. Clinical cancer research : an official journal of the American Association for Cancer Research. 28 (10) :2094-2109 Go to Pubmed
Aleksandar Obradovic, Diana Graves, Michael Korrer, Yu Wang, Sohini Roy, Abdullah Naveed, Yaomin Xu, Adam Luginbuhl, Joseph Curry, Michael Gibson, Kamran Idrees, Paula Hurley, Peng Jiang, Shirley Liu, Ravindra Uppaluri, Charles Drake, Andrea Califano, Young Kim .  2022.   Immunostimulatory Cancer-Associated Fibroblast Subpopulations Can Predict Immunotherapy Response in Head and Neck Cancer.. Clinical cancer research : an official journal of the American Association for Cancer Research. 28 (10) :2094-2109 Go to Pubmed
Aleksandar Obradovic, Diana Graves, Michael Korrer, Yu Wang, Sohini Roy, Abdullah Naveed, Yaomin Xu, Adam Luginbuhl, Joseph Curry, Michael Gibson, Kamran Idrees, Paula Hurley, Peng Jiang, Shirley Liu, Ravindra Uppaluri, Charles Drake, Andrea Califano, Young Kim .  2022.   Immunostimulatory Cancer-Associated Fibroblast Subpopulations Can Predict Immunotherapy Response in Head and Neck Cancer.. Clin Cancer Res. 28 (10) :2094-2109 Go to Pubmed
Francesco Cambuli, Veronica Foletto, Alessandro Alaimo, Dario De Felice, Francesco Gandolfi, Maria Palumbieri, Michela Zaffagni, Sacha Genovesi, Marco Lorenzoni, Martina Celotti, Emiliana Bertossio, Giosuè Mazzero, Arianna Bertossi, Alessandra Bisio, Francesco Berardinelli, Antonio Antoccia, Marco Gaspari, Mattia Barbareschi, Michelangelo Fiorentino, Michael Shen, Massimo Loda, Alessandro Romanel, Andrea Lunardi .  2022.   Intra-epithelial non-canonical Activin A signaling safeguards prostate progenitor quiescence.. EMBO Rep. 23 (5) :e54049 Go to Pubmed
Kerry Goodman, Phinikoula Katsamba, Rotem Rubinstein, Goran Ahlsen, Fabiana Bahna, Seetha Mannepalli, Hanbin Dan, Rosemary Sampogna V, Lawrence Shapiro, Barry Honig .  2022.   How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition.. eLife. 11 Go to Pubmed
Sho Iketani, Lihong Liu, Yicheng Guo, Liyuan Liu, Jasper Chan, Yiming Huang, Maple Wang, Yang Luo, Jian Yu, Hin Chu, Kenn Chik, Terrence Yuen, Michael Yin, Magdalena Sobieszczyk, Yaoxing Huang, Kwok-Yung Yuen, Harris Wang, Zizhang Sheng, David Ho .  2022.   Antibody evasion properties of SARS-CoV-2 Omicron sublineages.. Nature. 604 (7906) :553-556 Go to Pubmed
Kazuya Masuda, Adam Kornberg, Jonathan Miller, Sijie Lin, Nathan Suek, Theo Botella, Kerim Secener, Alyssa Bacarella, Liang Cheng, Matthew Ingham, Vilma Rosario, Ahmed Al-Mazrou, Steven Lee-Kong, Ravi Kiran, Marlon Stoeckius, Peter Smibert, Armando Del Portillo, Paul Oberstein, Peter Sims, Kelley Yan, Arnold Han .  2022.   Multiplexed single-cell analysis reveals prognostic and nonprognostic T cell types in human colorectal cancer.. JCI insight. 7 (7) Go to Pubmed
Gabriele Cerutti, Yicheng Guo, Lihong Liu, Liyuan Liu, Zhening Zhang, Yang Luo, Yiming Huang, Harris Wang, David Ho, Zizhang Sheng, Lawrence Shapiro .  2022.   Cryo-EM structure of the SARS-CoV-2 Omicron spike.. Cell reports. 38 (9) :110428 Go to Pubmed
Alberto Bartolomé, Nina Suda, Junjie Yu, Changyu Zhu, Jinsook Son, Hongxu Ding, Andrea Califano, Domenico Accili, Utpal Pajvani .  2022.   Notch-mediated Ephrin signaling disrupts islet architecture and β cell function.. JCI insight. 7 (6) Go to Pubmed
Víctor Arrieta, Andrew Chen, Robert Kane, Seong Kang, Cynthia Kassab, Crismita Dmello, Junfei Zhao, Kirsten Burdett, Pavan Upadhyayula, Catalina Lee-Chang, Joseph Shilati, Dinesh Jaishankar, Li Chen, Andrew Gould, Daniel Zhang, Jinzhou Yuan, Wenting Zhao, Xiaoyang Ling, Jared Burks, Brice Laffleur, Christina Amidei, Jeffrey Bruce, Rimas Lukas V, Jonathan Yamaguchi, David Cieremans, Gerson Rothschild, Uttiya Basu, Matthew McCord, Daniel Brat, Hui Zhang, Lee Cooper, Bin Zhang, Peter Sims, Tim Cloughesy, Robert Prins, Peter Canoll, Roger Stupp, Amy Heimberger, Craig Horbinski, Fabio Iwamoto, Raul Rabadan, Adam Sonabend .  2022.   Publisher Correction: ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma.. Nature cancer. 3 (3) :373 Go to Pubmed
Víctor Arrieta, Andrew Chen, Robert Kane, Seong Kang, Cynthia Kassab, Crismita Dmello, Junfei Zhao, Kirsten Burdett, Pavan Upadhyayula, Catalina Lee-Chang, Joseph Shilati, Dinesh Jaishankar, Li Chen, Andrew Gould, Daniel Zhang, Jinzhou Yuan, Wenting Zhao, Xiaoyang Ling, Jared Burks, Brice Laffleur, Christina Amidei, Jeffrey Bruce, Rimas Lukas V, Jonathan Yamaguchi, David Cieremans, Gerson Rothschild, Uttiya Basu, Matthew McCord, Daniel Brat, Hui Zhang, Lee Cooper, Bin Zhang, Peter Sims, Tim Cloughesy, Robert Prins, Peter Canoll, Roger Stupp, Amy Heimberger, Craig Horbinski, Fabio Iwamoto, Raul Rabadan, Adam Sonabend .  2022.   Publisher Correction: ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma.. Nature cancer. 3 (3) :373 Go to Pubmed
Pasquale Laise, Megan Stanifer, Gideon Bosker, Xiaoyun Sun, Sergio Triana, Patricio Doldan, Federico La Manna, Marta De Menna, Ronald Realubit, Sergey Pampou, Charles Karan, Theodore Alexandrov, Marianna de Julio, Andrea Califano, Steeve Boulant, Mariano Alvarez .  2022.   A Model for Network-Based Identification and Pharmacological Targeting of Aberrant, Replication-Permissive Transcriptional Programs Induced by Viral Infection.. Research square. Go to Pubmed
Na Zhu, Michael Pauciulo, Carrie Welch, Katie Lutz, Anna Coleman, Claudia Gonzaga-Jauregui, Jiayao Wang, Joseph Grimes, Lisa Martin, Hua He, PAH Investigators, Yufeng Shen, Wendy Chung, William Nichols .  2022.   Correction to: Novel risk genes and mechanisms implicated by exome sequencing of 2572 individuals with pulmonary arterial hypertension.. Genome medicine. 14 (1) :12 Go to Pubmed
Zoila Lopez-Bujanda, Michael Haffner, Matthew Chaimowitz, Nivedita Chowdhury, Nicholas Venturini, Radhika Patel, Aleksandar Obradovic, Corey Hansen, Joanna Jacków, Janielle Maynard, Karen Sfanos, Cory Abate-Shen, Charles Bieberich, Paula Hurley, Mark Selby, Alan Korman, Angela Christiano, Angelo De Marzo, Charles Drake .  2021.   Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression.. Nat Cancer. 2 (8) :803-818 Go to Pubmed
Víctor Arrieta, Andrew Chen, Robert Kane, Seong Kang, Cynthia Kassab, Crismita Dmello, Junfei Zhao, Kirsten Burdett, Pavan Upadhyayula, Catalina Lee-Chang, Joseph Shilati, Dinesh Jaishankar, Li Chen, Andrew Gould, Daniel Zhang, Jinzhou Yuan, Wenting Zhao, Xiaoyang Ling, Jared Burks, Brice Laffleur, Christina Amidei, Jeffrey Bruce, Rimas Lukas V, Jonathan Yamaguchi, David Cieremans, Gerson Rothschild, Uttiya Basu, Matthew McCord, Daniel Brat, Hui Zhang, Lee Cooper, Bin Zhang, Peter Sims, Tim Cloughesy, Robert Prins, Peter Canoll, Roger Stupp, Amy Heimberger, Craig Horbinski, Fabio Iwamoto, Raul Rabadan, Adam Sonabend .  2021.   ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma.. Nature cancer. 2 (12) :1372-1386 Go to Pubmed
Víctor Arrieta, Andrew Chen, Robert Kane, Seong Kang, Cynthia Kassab, Crismita Dmello, Junfei Zhao, Kirsten Burdett, Pavan Upadhyayula, Catalina Lee-Chang, Joseph Shilati, Dinesh Jaishankar, Li Chen, Andrew Gould, Daniel Zhang, Jinzhou Yuan, Wenting Zhao, Xiaoyang Ling, Jared Burks, Brice Laffleur, Christina Amidei, Jeffrey Bruce, Rimas Lukas V, Jonathan Yamaguchi, David Cieremans, Gerson Rothschild, Uttiya Basu, Matthew McCord, Daniel Brat, Hui Zhang, Lee Cooper, Bin Zhang, Peter Sims, Tim Cloughesy, Robert Prins, Peter Canoll, Roger Stupp, Amy Heimberger, Craig Horbinski, Fabio Iwamoto, Raul Rabadan, Adam Sonabend .  2021.   ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma.. Nat Cancer. 2 (12) :1372-1386 Go to Pubmed
Daniel Freedberg, Miles Richardson, Mary Nattakom, Jacky Cheung, Elissa Lynch, Philip Zachariah, Harris Wang .  2022.   Are There Bad ICU Rooms? Temporal Relationship between Patient and ICU Room Microbiome, and Influence on Vancomycin-Resistant Colonization.. mSphere. 7 (1) :e0100721 Go to Pubmed
Daniel Freedberg, Miles Richardson, Mary Nattakom, Jacky Cheung, Elissa Lynch, Philip Zachariah, Harris Wang .  2022.   Are There Bad ICU Rooms? Temporal Relationship between Patient and ICU Room Microbiome, and Influence on Vancomycin-Resistant Colonization.. mSphere. 7 (1) :e0100721 Go to Pubmed
Eugene Douglass, Robert Allaway, Bence Szalai, Wenyu Wang, Tingzhong Tian, Adrià Fernández-Torras, Ron Realubit, Charles Karan, Shuyu Zheng, Alberto Pessia, Ziaurrehman Tanoli, Mohieddin Jafari, Fangping Wan, Shuya Li, Yuanpeng Xiong, Miquel Duran-Frigola, Martino Bertoni, Pau Badia-I-Mompel, Lídia Mateo, Oriol Guitart-Pla, Verena Chung, DREAM Consortium, Jing Tang, Jianyang Zeng, Patrick Aloy, Julio Saez-Rodriguez, Justin Guinney, Daniela Gerhard, Andrea Califano .  2022.   A community challenge for a pancancer drug mechanism of action inference from perturbational profile data.. Cell reports. Medicine. 3 (1) :100492 Go to Pubmed
Bhairavi Swaminathan, Seock-Won Youn, L Naiche, Jing Du, Stephanie Villa, Jordan Metz, Huijuan Feng, Chaolin Zhang, Raphael Kopan, Peter Sims, Jan Kitajewski .  2022.   Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration.. Scientific reports. 12 (1) :1655 Go to Pubmed
Elise Flynn, Athena Tsu, Silva Kasela, Sarah Kim-Hellmuth, François Aguet, Kristin Ardlie, Harmen Bussemaker, Pejman Mohammadi, Tuuli Lappalainen .  2022.   Transcription factor regulation of eQTL activity across individuals and tissues.. PLoS genetics. 18 (1) :e1009719 Go to Pubmed
Benjamin Hobson, Se Choi, Eugene Mosharov V, Rajesh Soni, David Sulzer, Peter Sims .  2022.   Subcellular proteomics of dopamine neurons in the mouse brain.. eLife. 11 Go to Pubmed
Marta Galán-Díez, Florence Borot, Abdullah Ali, Junfei Zhao, Eva Gil-Iturbe, Xiaochuan Shan, Na Luo, Yongfeng Liu, Xi-Ping Huang, Brygida Bisikirska, Rossella Labella, Irwin Kurland, Bryan Roth, Matthias Quick, Siddhartha Mukherjee, Raul Rabadan, Martin Carroll, Azra Raza, Stavroula Kousteni .  2022.   Subversion of Serotonin Receptor Signaling in Osteoblasts by Kynurenine Drives Acute Myeloid Leukemia.. Cancer discovery. 12 (4) :1106-1127 Go to Pubmed
Smadar Shilo, Anastasia Godneva, Marianna Rachmiel, Tal Korem, Yuval Bussi, Dmitry Kolobkov, Tal Karady, Noam Bar, Bat Wolf, Yitav Glantz-Gashai, Michal Cohen, Nehama Zuckerman-Levin, Naim Shehadeh, Noah Gruber, Neriya Levran, Shlomit Koren, Adina Weinberger, Orit Pinhas-Hamiel, Eran Segal .  2022.   The Gut Microbiome of Adults With Type 1 Diabetes and Its Association With the Host Glycemic Control.. Diabetes care. 45 (3) :555-563 Go to Pubmed
Panagiota Agrafioti, Joshua Morin-Baxter, Kranthi Tanagala, Sunil Dubey, Peter Sims, Evanthia Lalla, Fatemeh Momen-Heravi .  2022.   Decoding the role of macrophages in periodontitis and type 2 diabetes using single-cell RNA-sequencing.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 36 (2) :e22136 Go to Pubmed
Benjamin Hobson, Linghao Kong, Maria Angelo, Ori Lieberman, Eugene Mosharov V, Etienne Herzog, David Sulzer, Peter Sims .  2022.   Subcellular and regional localization of mRNA translation in midbrain dopamine neurons.. Cell reports. 38 (2) :110208 Go to Pubmed
Lihong Liu, Sho Iketani, Yicheng Guo, Jasper Chan, Maple Wang, Liyuan Liu, Yang Luo, Hin Chu, Yiming Huang, Manoj Nair, Jian Yu, Kenn Chik, Terrence Yuen, Chaemin Yoon, Kelvin To, Honglin Chen, Michael Yin, Magdalena Sobieszczyk, Yaoxing Huang, Harris Wang, Zizhang Sheng, Kwok-Yung Yuen, David Ho .  2022.   Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2.. Nature. 602 (7898) :676-681 Go to Pubmed
John Christin, Michael Shen .  2022.   Modeling tumor plasticity in organoid models of human cancer.. Trends in cancer. 8 (3) :161-163 Go to Pubmed
Tyler Joseph, Philippe Chlenski, Aviya Litman, Tal Korem, Itsik Pe'er .  2022.   Accurate and robust inference of microbial growth dynamics from metagenomic sequencing reveals personalized growth rates.. Genome research. 32 (3) :558-568 Go to Pubmed
Jinsook Son, Hongxu Ding, Thomas Farb, Alexander Efanov, Jiajun Sun, Julie Gore, Samreen Syed, Zhigang Lei, Qidi Wang, Domenico Accili, Andrea Califano .  2021.   BACH2 inhibition reverses β cell failure in type 2 diabetes models.. J Clin Invest. 131 (24) Go to Pubmed
Ross McBee, Matt Lucht, Nikita Mukhitov, Miles Richardson, Tarun Srinivasan, Dechuan Meng, Haorong Chen, Andrew Kaufman, Max Reitman, Christian Munck, Damen Schaak, Christopher Voigt, Harris Wang .  2022.   Engineering living and regenerative fungal-bacterial biocomposite structures.. Nature materials. 21 (4) :471-478 Go to Pubmed
Maya Poon, Eve Byington, Wenzhao Meng, Masaru Kubota, Rei Matsumoto, Alba Grifoni, Daniela Weiskopf, Pranay Dogra, Nora Lam, Peter Szabo, Basak Ural, Steven Wells, Aaron Rosenfeld, Maigan Brusko, Todd Brusko, Thomas Connors, Alessandro Sette, Peter Sims, Eline Prak, Yufeng Shen, Donna Farber .  2021.   Heterogeneity of human anti-viral immunity shaped by virus, tissue, age, and sex.. Cell reports. 37 (9) :110071 Go to Pubmed
Carlotta Ronda, Harris Wang .  2022.   Engineering temporal dynamics in microbial communities.. Current opinion in microbiology. 65 :47-55 Go to Pubmed
Carlotta Ronda, Harris Wang .  2022.   Engineering temporal dynamics in microbial communities.. Current opinion in microbiology. 65 :47-55 Go to Pubmed
Carlotta Ronda, Harris Wang .  2022.   Engineering temporal dynamics in microbial communities.. Current opinion in microbiology. 65 :47-55 Go to Pubmed
Andrew Lassman, Patrick Wen, Martin van den Bent, Scott Plotkin, Annemiek Walenkamp, Adam Green, Kai Li, Christopher Walker, Hua Chang, Sharon Tamir, Leah Henegar, Yao Shen, Mariano Alvarez, Andrea Califano, Yosef Landesman, Michael Kauffman, Sharon Shacham, Morten Mau-Sørensen .  2022.   A Phase II Study of the Efficacy and Safety of Oral Selinexor in Recurrent Glioblastoma.. Clin Cancer Res. 28 (3) :452-460 Go to Pubmed
Smadar Shilo, Anastasia Godneva, Marianna Rachmiel, Tal Korem, Dmitry Kolobkov, Tal Karady, Noam Bar, Bat Wolf, Yitav Glantz-Gashai, Michal Cohen, Nehama Levin, Naim Shehadeh, Noah Gruber, Neriya Levran, Shlomit Koren, Adina Weinberger, Orit Pinhas-Hamiel, Eran Segal .  2022.   Prediction of Personal Glycemic Responses to Food for Individuals With Type 1 Diabetes Through Integration of Clinical and Microbial Data.. Diabetes care. 45 (3) :502-511 Go to Pubmed
Heike Blockus, Sebi Rolotti V, Miklos Szoboszlay, Eugénie Peze-Heidsieck, Tiffany Ming, Anna Schroeder, Nuno Apostolo, Kristel Vennekens, Phinikoula Katsamba, Fabiana Bahna, Seetha Mannepalli, Goran Ahlsen, Barry Honig, Lawrence Shapiro, Joris de Wit, Attila Losonczy, Franck Polleux .  2021.   Synaptogenic activity of the axon guidance molecule Robo2 underlies hippocampal circuit function.. Cell Rep. 37 (3) :109828 Go to Pubmed
Evgeniya Schastnaya, Zrinka Nakic, Christoph Gruber, Peter Doubleday, Aarti Krishnan, Nathan Johns, Jimin Park, Harris Wang, Uwe Sauer .  2021.   Extensive regulation of enzyme activity by phosphorylation in Escherichia coli.. Nature communications. 12 (1) :5650 Go to Pubmed
Soonbum Park, Lijie Rong, Tomasz Owczarek, Matteo Di Bernardo, Rivka Shoulson, Chee-Wai Chua, Jaime Kim, Amir Lankarani, Prithi Chakrapani, Talal Syed, James McKiernan, David Solit, Michael Shen, Hikmat Al-Ahmadie, Cory Abate-Shen .  2021.   Novel mouse models of bladder cancer identify a prognostic signature associated with risk of disease progression.. Cancer Res. Go to Pubmed
Camila Prieto, Diu Nguyen, Zhaoqi Liu, Justin Wheat, Alexendar Perez, Saroj Gourkanti, Timothy Chou, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Arthur Chow, James Taggart, Angela Savino, Katerina Hoskova, Meera Dhodapkar, Alexandra Schurer, Trevor Barlowe, Ly Vu, Christina Leslie, Ulrich Steidl, Raul Rabadan, Michael Kharas .  2021.   Transcriptional control of CBX5 by the RNA binding proteins RBMX and RBMXL1 maintains chromatin state in myeloid leukemia.. Nat Cancer. 2 :741-757 Go to Pubmed
Edgar González-Buendia, Junfei Zhao, Lu Wang, Subhas Mukherjee, Daniel Zhang, Víctor Arrieta, Eric Feldstein, Robert Kane, Seong Kang, Catalina Lee-Chang, Aayushi Mahajan, Li Chen, Ronald Realubit, Charles Karan, Lisa Magnuson, Craig Horbinski, Stacy Marshall, Jann Sarkaria, Ahmed Mohyeldin, Ichiro Nakano, Mukesh Bansal, Charles James, Daniel Brat, Atique Ahmed, Peter Canoll, Raul Rabadan, Ali Shilatifard, Adam Sonabend .  2021.   TOP2B Enzymatic Activity on Promoters and Introns Modulates Multiple Oncogenes in Human Gliomas.. Clin Cancer Res. Go to Pubmed
Jimin Park, Harris Wang .  2021.   Systematic dissection of σ sequence diversity and function in bacteria.. Cell reports. 36 (8) :109590 Go to Pubmed
Claudia Capdevila, Maria Trifas, Jonathan Miller, Troy Anderson, Peter Sims, Kelley Yan .  2021.   Cellular origins and lineage relationships of the intestinal epithelium.. American journal of physiology. Gastrointestinal and liver physiology. 321 (4) :G413-G425 Go to Pubmed
Mohammed AlQuraishi .  2021.   Protein-structure prediction revolutionized.. Nature. 596 (7873) :487-488 Go to Pubmed
Karen Gomez, Raul Rabadan .  2021.   A persistent look at how tumours evade therapy.. Nature. 596 (7873) :491-493 Go to Pubmed
Juan Patiño-Galindo, Ioan Filip, Ratul Chowdhury, Costas Maranas, Peter Sorger, Mohammed AlQuraishi, Raul Rabadan .  2021.   Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2.. Genome Med. 13 (1) :124 Go to Pubmed
Nazim Bouatta, Peter Sorger, Mohammed AlQuraishi .  2021.   Protein structure prediction by AlphaFold2: are attention and symmetries all you need?. Acta Crystallogr D Struct Biol. 77 (Pt 8) :982-991 Go to Pubmed
Daniel Landsburg, Stefan Barta, Radhakrishnan Ramchandren, Connie Batlevi, Swaminathan Iyer, Kevin Kelly, Ivana Micallef, Sonali Smith, Don Stevens, Mariano Alvarez, Andrea Califano, Yao Shen, Gideon Bosker, Jefferson Parker, Raul Soikes, Elizabeth Martinez, Reinhard von Roemeling, Robert Martell, Yasuhiro Oki .  2021.   Fimepinostat (CUDC-907) in patients with relapsed/refractory diffuse large B cell and high-grade B-cell lymphoma: report of a phase 2 trial and exploratory biomarker analyses.. Br J Haematol. Go to Pubmed
Kendra Sweet, Bhavana Bhatnagar, Hartmut Döhner, Will Donnellan, Olga Frankfurt, Michael Heuser, Vamsi Kota, Hongtao Liu, Emmanuel Raffoux, Gail Roboz, Christoph Röllig, Margaret Showel, Stephen Strickland, Susana Vives, Shijie Tang, Thaddeus Unger, Anita Joshi, Yao Shen, Mariano Alvarez, Andrea Califano, Marsha Crochiere, Yosef Landesman, Michael Kauffman, Jatin Shah, Sharon Shacham, Michael Savona, Pau Montesinos .  2021.   A 2:1 randomized, open-label, phase II study of selinexor vs. physician's choice in older patients with relapsed or refractory acute myeloid leukemia.. Leuk Lymphoma. :1-12 Go to Pubmed
Gulam Manji, Brian Van Tine, Shing Lee, Alexander Raufi, Ilenia Pellicciotta, Angela Hirbe, Jaya Pradhan, Andrew Chen, Raul Rabadan, Gary Schwartz .  2021.   A Phase I Study of the Combination of Pexidartinib and Sirolimus to Target Tumor-Associated Macrophages in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors.. Clin Cancer Res. Go to Pubmed
Arianna Giacobbe, Cory Abate-Shen .  2021.   Modeling metastasis in mice: a closer look.. Trends Cancer. 7 (10) :916-929 Go to Pubmed
Jimin Park, Sung Yim, Harris Wang .  2021.   High-Throughput Transcriptional Characterization of Regulatory Sequences from Bacterial Biosynthetic Gene Clusters.. ACS synthetic biology. 10 (8) :1859-1873 Go to Pubmed
Kaiyi Zhu, Lingyi Cai, Chenqian Cui, Juan Toyos, Dimitris Anastassiou .  2021.   Single-cell analysis reveals the pan-cancer invasiveness-associated transition of adipose-derived stromal cells into COL11A1-expressing cancer-associated fibroblasts.. PLoS Comput Biol. 17 (7) :e1009228 Go to Pubmed
Regina Troyanovsky, Alina Sergeeva, Indrajyoti Indra, Chi-Shuo Chen, Rei Kato, Lawrence Shapiro, Barry Honig, Sergey Troyanovsky .  2021.   Sorting of cadherin-catenin-associated proteins into individual clusters.. Proceedings of the National Academy of Sciences of the United States of America. 118 (29) Go to Pubmed
Regina Troyanovsky, Alina Sergeeva, Indrajyoti Indra, Chi-Shuo Chen, Rei Kato, Lawrence Shapiro, Barry Honig, Sergey Troyanovsky .  2021.   Sorting of cadherin-catenin-associated proteins into individual clusters.. Proc Natl Acad Sci U S A. 118 (29) Go to Pubmed
Seth Taylor, Gabriel Santpere, Alexis Weinreb, Alec Barrett, Molly Reilly, Chuan Xu, Erdem Varol, Panos Oikonomou, Lori Glenwinkel, Rebecca McWhirter, Abigail Poff, Manasa Basavaraju, Ibnul Rafi, Eviatar Yemini, Steven Cook, Alexander Abrams, Berta Vidal, Cyril Cros, Saeed Tavazoie, Nenad Sestan, Marc Hammarlund, Oliver Hobert, David Miller .  2021.   Molecular topography of an entire nervous system.. Cell. 184 (16) :4329-4347.e23 Go to Pubmed
Zoila Lopez-Bujanda, Aleksandar Obradovic, Thomas Nirschl, Laura Crowley, Rodney Macedo, Alexandros Papachristodoulou, Timothy O'Donnell, Uri Laserson, Jelani Zarif, Ran Reshef, Tiezheng Yuan, Mithil Soni, Emmanuel Antonarakis, Michael Haffner, Benjamin Larman, Michael Shen, Pawel Muranski, Charles Drake .  2021.   TGM4: an immunogenic prostate-restricted antigen.. J Immunother Cancer. 9 (6) Go to Pubmed
Qing Meng, Qiuqiang Gao, Shebli Mehrazarin, Kamonchanok Tangwanichgapong, Yu Wang, Yiming Huang, Yutong Pan, Samuel Robinson, Ziwen Liu, Amirali Zangiabadi, Renate Lux, Panos Papapanou, Edward Guo, Harris Wang, Luke Berchowitz, Yiping Han .  2021.   Fusobacterium nucleatum secretes amyloid-like FadA to enhance pathogenicity.. EMBO reports. 22 (7) :e52891 Go to Pubmed
Peter Freddolino, Haley Amemiya, Thomas Goss, Saeed Tavazoie .  2021.   Dynamic landscape of protein occupancy across the Escherichia coli chromosome.. PLoS Biol. 19 (6) :e3001306 Go to Pubmed
Matthew Kearney, Lauren Franks, Shing Lee, Amy Tiersten, Della Makower, Tessa Cigler, Prabhjot Mundi, Dow-Chung Chi, Anupama Goel, Pam Klein, Eleni Andreopoulou, Joseph Sparano, Meghna Trivedi, Melissa Accordino, Andrea Califano, Dawn Hershman, Jose Silva, Kevin Kalinsky .  2021.   Phase I/II trial of ruxolitinib in combination with trastuzumab in metastatic HER2 positive breast cancer.. Breast Cancer Res Treat. 189 (1) :177-185 Go to Pubmed
Hans Koss, Barry Honig, Lawrence Shapiro, Arthur Palmer .  2021.   Dimerization of Cadherin-11 involves multi-site coupled unfolding and strand swapping.. Structure. Go to Pubmed
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